This 1994 book provides a fascinating account of the fast-moving field of lipase research. The contributions, written by active research workers, summarise developments in the field and give access to recent literature. It covers both the lipases proper (triglyceride lipases and the phospholipases. It gives a comprehensive picture of the state of knowledge of these enzymes, with a strong bias towards the fields that are attracting the greatest attention: their detailed molecular structure, their mechanism of action, their position in the evolution of enzymes, and their application both in the laboratory and industry. The book will continue to be of interest to those working in universities, in research institutes and in companies specialising in biotechnology. The book will also be a useful reference book for postgraduate students entering this field of research.
• Useful reference work • Comprehensive survey of the lipase field
Contents
1. Sequence comparisons within the lipase family; 2. A sequence analysis of lipases, esterases and related proteins; 3. Lipases from plants; 4. Three-dimensional structures of two lipases from filamentous fungi; 5. Structural aspects of phospholipase C; 6. Phospholipase A2: mechanism and structure; 7. Structure and mechanism of human pancreatic lipase; 8. Kinetics of triglyceride lipases; 9. Gastric lipases: cellular, biochemical and kinetic aspects; 10. Lipase inhibitors; 11. Substrates for phospholipase C and sphigomyelinase; 12. Isolation and purification of lipases; 13. Industrial applications of lipases; 14. Lipases and phospholipases in organic synthesis; 15. Medical aspects of triglyceride lipases; 16. Protein engineering of lipases; Index.
Review
Review of the hardback: 'An excellent overview of current knowledge of lipases, including phospholipases, their biochemistry and their applications particularly in biotechnology.' Microbiology
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