This advanced text, first published in 2006, takes a developmental approach to the presentation of our understanding of how vertebrates construct a retina. Written by experts in the field, each of the seventeen chapters covers a specific step in the process, focusing on the underlying molecular, cellular, and physiological mechanisms. There is also a special section on emerging technologies, including genomics, zebrafish genetics, and stem cell biology that are starting to yield important insights into retinal development. Primarily aimed at professionals, both biologists and clinicians working with the retina, this book provides a concise view of vertebrate retinal development. Since the retina is 'an approachable part of the brain', this book will also be attractive to all neuroscientists interested in development, as processes required to build this exquisitely organized system are ultimately relevant to all other parts of the central nervous system.
• Each chapter includes a short introduction and ends with concluding remarks helping the reader to summarise the key features of the chapter and link the information with other chapters • Illustrations are used throughout to help the reader to visualise the concepts discussed and an accompanying website provides additional resources including related movies • Chapters written by experts in the field with the material organised as an integrated text making the book accessible to students, scientists and clinicians who are not necessarily experts in the retina
Contents
Foreword Alan Bird; Preface; 1. Introduction Rachel O. L. Wong; 2. Formation of the eye field Michael E. Zuber and William A. Harris; 3. Retinal neurogenesis David H. Rapaport; 4. Cell migration Leanne Godinho and Brian Link; 5. Cell determination Michalis Agathocleous and William A. Harris; 6. Neurotransmitters and neurotrophins Rachael A. Pearson; 7. Emergence of the fovea Anita Hendrickson and Jan M. Provis; 8. Optic nerve formation David W. Sretavan; 9. Glial cells in the developing retina Kathleen Zahs and Manuel Esguerra; 10. Retinal mosaics Stephen J. Eglen and Lucia Galli-Resta; 11. Programmed cell death Rafael Linden and Benjamin E Reese; 12. Dendritic growth Jeff S. Mumm and Christian Lohmann; 13. Synaptogenesis and early neural activity Evelyne Sernagor; 14. Emergence of light responses Evelyne Sernagor and Leo M. Chalupa; New Perspectives: 15. Regeneration (and stem cells) Jennie Close and Thomas A. Reh; 16. Genomics Seth Blackshaw; 17. Zebrafish models of retinal development and disease James M Fadool and John E. Dowling.
Reviews
Review of the hardback: 'Edited by leading members of the field, Sernagor, Eglen, Harris, and Wong, the 17 chapters of Retinal Development are well organized, clearly written, nicely illustrated, and succinct. The volume is carefully edited to avoid the redundancy that often weighs down a multi-author volume. In fact it is so well done that I may leave it on our lunchroom table - and see what develops.' Peter Sterling
Review of the hardback: 'This book is an excellent resource for those working in the field of retinal biology, developmental neuroscience, or developmental biology.' Professor Connie Cepko, Harvard University
Review of the hardback: ' … an excellent overview on the different steps of retinal development and the current knowledge in the field, starting from the early specification of the eye-field in the embryo up to the light-evoked responses in the retina after birth. It therefore brings out beautifully the broad spectrum of research and its importance for general developmental neurobiology … Retinal Development is a comprehensive book that features a collection of excellent reviews. but rather than giving only an up-to-date view on the status quo in retinal research, it goes a step further and brings out some of the important open questions still to be answered, to understand the development of the retina as well as the nervous system in general. The book is therefore not only appropriate for specialists in the field of retinal research, but certainly for a wider scientific audience.' Robert Hindges, MRC Centre for Developmental Neurobiology, Kings College London
Review of the hardback: ' … until now, a reference resource in the form of a review collection that guides the reader through the state-of-the-art approaches for studying retinal development has not been available … as such, the book Retinal Development is especially welcome and is also a delightful read.' Development
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