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Endothelial Biomedicine
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Details

  • 81 tables
  • Page extent: 1894 pages
  • Size: 279 x 215 mm
  • Weight: 4.012 kg

Library of Congress

  • Dewey number: 611/.0187
  • Dewey version: 22
  • LC Classification: QP88.45 .E49 2007
  • LC Subject headings:
    • Endothelium
    • Endothelium--physiology
    • Endothelial Cells--physiology
    • Endothelium--physiopathology

Library of Congress Record

Hardback

 (ISBN-13: 9780521853767)

The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all areas of the human body. Clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. The endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume bridges the bench-to-bedside gap in endothelial biomedicine, advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. It's interdisciplinary approach, which draws on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

• Employs multidisciplinary and interdisciplinary approaches to promote the endothelium as a clinically relevant organ • A single definitive about the endothelium at the level of the single cell, the blood vessel and the whole organism • Provides new insights into the endothelium as an organizing principle in health and disease

Contents

Part I. Context; Part II. Endothelial Cell as Input-Output Device; Part III. Vascular Bed/Organ Structure and Function in Health and Disease; Part IV. Diagnosis and Treatment; Part V. Challenges and Opportunities.

Contributors

Manfred D. Laubichler , William C. Aird, Jane Maienshein,Warren W. Burggren, Carl L. Reiber, J. Douglas Coffin, Kenneth R. Olson, Pavan K. Cheruvu, Daniel Gale, Ann M. Dvorak, David Haig, H. William Detrich III, José M. Icardo, Glenn J. Tattersall, Thomas J. Poole, John E. Rush, Alan R. Hargens, Knut Pettersson, Ronald W. Millard, Klaus D. Jürgens, John H. McVey Randolf M. Nesse, Alan Weder, S. Boyd Eaton, Loren Cordain, Anthony Sebastian, David Haig, Aldo Ciau-Uitz, Claire Fernandez, Roger Patient Sameer S. Chopra, Tao P. Zhong, Cam Patterson Takashi Mikawa, 22. Eckhard Lammert, Peter Lloyd Jones ,Steven Moskowitz, Kenneth L. Kaplan, Daniel L. Schodek, Dexter Pratt Helmut G. Augustin, Peter F. Davies, Gregg L. Semenza, Mitchell L. Halperin, Kamel S. Kamel, Jordan S. Pober, Debarata Mukhopadhyay, Resham Bhattacharya, Deborah A. Hughes, Xue Wang, Augustine M. K. Choi, Stefan W. Ryter, Masahiro Murakami, Arye Elfenbein, Michael Simons, Barbara J. Ballerman, Sareh Parangi, Jack Lawler, Diane Bielenberg, Peter Kurschat, Michael Klagsbrun, Helmut G. Augustin, Daniel Dumont, Kye Won Park, Lisa D. Urness, Dean Y. Li, Yasuhiro Funahashi, Carrie J. Shawber, Jan Kitajewski, Kaikobad Irani, Silvia Deaglio, Simon C. Robson, Eugene Tkachenko, John M. Rhodes, Michael Simons, Timothy Hla, Jaswinder Kaur, Paul Kubes, Jean-Luc Wautier, Ann Marie Schmidt, Anne Nicholson-Weller, Robert Colman, Kalpna Gupta, Elliot J. Stephenson, Jay W. Fox, Solange M. T. Serrano, Qing Chen, Kristen Clancy, Wan-Chao Wang, Sharon S. Evans, Bryan Belikoff, Wende R. Reenstra, Jon A. Buras, Deborah A. Quinn, Charles A. Hales, Alf O. Brubakk, Olav S. Eftedal, Ulrik Wisløff, Ulrik Wisløff, Per M. Haram, Alf O. Brubakk, Nicholas L. M. Cruden, David J. Webb, Janice V. Meck, Ralph E. Purdy, Howard D. Beall, Mark W. Majesky, Shivalika Handa, Karolina Kolodziejska, Mansoor Husain, Sruti Shiva, Mark T. Gladwin, Volker Vielhauer, Xavier Cullere, Tanya Mayadas, Patricia B. Maguire, Orina Belton, Niaobh O'Donoghue, Sandra Austin, Judith Coppinger, Jian Li, Frank W. Sellke, David Semela, Vijay Shah, Haruki Senoo Susan E. Quaggin, Michael Simons, Rolf Kinne, Ann M. Dvorak, Charles J. Lowenstein, Craig N. Morrell, Munekazu Yamakuchi, Lucy A. Carver, Jan E. Schnitzer, Radu V. Stan, Bernard M. van den Berg, Max Nieuwdorp, Erik Stroes, Hans Vink, Christopher V. Carman, Joseph H. McCarty, Richard O. Hynes, Alan S. Verkman, Xiaoqiang Yao, Ichiro Shiojima, Kenneth Wals, Natalia V. Bogatcheva, Alexander D. Verin, Alex Toker, Allan Murray, Arne Ostman, Kai Kapper, Anna Cattelino, Stefan Liebner, Kaiser M. Bijli, Arshad Rahman, Jonathan D. Brown, Jorge Plutzky, Takashi Minami, Peter Oettgen, Levon M. Khachigian, Valerie C. Midgley, Zhiyong Lin, Mukesh K. Jain, Takashi Minami, Md. Ruhul Abid, Stephen R. Archacki, Sun-Ah You, Quansheng Xi, Qing Wang, Frank Kuhnert, Heidi Stuhlmann, Neville Young, Peter Koopman, Robert Benezra, Erik Henke, Lucy A. Carver, Jan E. Schnitzer, Amado J. Zurita, Wadih Arap, Renata Pasqualini,Tom Diacovo, Alan E. Mast, Gernot Schabbauer, Nigel Mackman, Marlies Van de Wouwer, Edward M. Conway, Nicholas W. Shworak, Nicholas W. Shworak Marlies Van de Wouwer, Edward M. Conway, Bjorn Dahlback, William C. Sessa, Hong Pyo Kim, Stefan W. Ryter, Augustine M. K. Choi, Kenneth K. Wu, Joe G. N. Garcia, F. William Luscinskas, Peter J. Newman, Debra K. Newman, Rodger P. McEver, Silvia Muro, David Milstone, Elizabeth O. Harrington, Qing Lu, Sharon Rounds, Andrew H. Lichtman, Mourad Toporsian, Michelle Letarte, Christian Weidenfeller, Eric V. Shusta, Kevin J. Tracey, Christine N. Metz, Laura Benjamin, Troy Stevens, Elizabeth Wagner, Aigul Moldobaeva, Mark L. Martinez, Guy A. Zimmerman, Norbert F. Voelkel, Mark R. Nicolls, Norbert F. Voelkel, Laimute Taraseviciene-Stewart, Shampa Chatterjee, Aron B. Fisher, Myron I. Cybulsky, Laurie D. DeLeve. Winston Dunn, Vijay Shah, Ossama A. Hatoum, David G. Binion,

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