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Heterotopic Growth of Dysplastic Cerebellum in Frontal Encephalocele in an Infant of a Diabetic Mother

Published online by Cambridge University Press:  18 September 2015

Harvey B. Sarnat ,
Daphne E. deMello ,
John D. Blair  and
Saeeda Y. Siddiqui
Harvey B. Sarnat*
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
Daphne E. deMello
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
John D. Blair
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
Saeeda Y. Siddiqui
Affiliation:
Departments of Paediatrics (Neurology) and Pathology, University of Calgary Faculty of Medicine, Calgary, Alberta and the Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA
*
University of Calgary Faculty of Medicine, Alberta Children’s Hospital, 1820 Richmond Road, S.W., Calgary, Alberta, T2T 5C7
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Summary:

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An infant of a diabetic mother lived 13 days after birth. She had a small dysplastic 12.6 gm. brain, partly forming a frontal encephalocele. The uncleaved forebrain contained a mass of poorly organized heterotopic cerebellar cortex. The cerebellum itself had normal lamination, but was small and continuous with the dysplastic tissue. The ventricular system was absent except for a few midline ependymal rosettes, and the cerebral cortex was not developed. The cerebellar dysplasia resembled a proliferative and invasive lesion by its rostral extension.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 9 , Issue 1 , February 1982 , pp. 31 - 35
Copyright
Copyright © Canadian Neurological Sciences Federation 1982

References

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