Hostname: page-component-848d4c4894-5nwft Total loading time: 0 Render date: 2024-06-09T09:05:52.848Z Has data issue: false hasContentIssue false

Pre-conceptual counselling in cardiology patients: still work to do and still missed opportunities. A comparison between 2015 and 2019 in women with cardiac disease attending combined obstetric cardiology clinics. Should the European Guidelines change anything?

Published online by Cambridge University Press:  25 May 2021

Chethan R. Kasargod Prabhakar*
Affiliation:
Queen Elizabeth Hospital, Birmingham, UK
Daisy Pamment
Affiliation:
University of Birmingham Medical School, Birmingham, UK
Peter J. Thompson
Affiliation:
Birmingham Women’s Hospital, Birmingham, UK
Hsu Chong
Affiliation:
The Rosie Maternity Hospital, Cambridge, UK
Sara A. Thorne
Affiliation:
Toronto General Hospital, Toronto, ON, Canada
Caroline Fox
Affiliation:
Birmingham Women’s Hospital, Birmingham, UK
Katie Morris
Affiliation:
Birmingham Women’s, Birmingham, UK
Lucy H. Hudsmith
Affiliation:
Queen Elizabeth Hospital, Birmingham, UK
*
Author for correspondence: Chethan R. Kasargod Prabhakar Queen Elizabeth Hospital Birmingham, Birmingham, B15 2GW. E-mail: kasargod.chethan@gmail.com

Abstract

Women with underlying cardiac conditions have an increased risk of adverse pregnancy outcomes. Counselling reproductive age women with heart disease is important to assist them in deciding whether to pursue pregnancy, to ensure their best cardiovascular status prior to pregnancy, and that they understand the risks of pregnancy for them and baby. This also provides an opportunity to explore management strategies to reduce risks. For this growing cohort of women, there is a great need for pre-conceptual counselling.

This retrospective comparative audit assessed new referrals and pre-conceptual counselling of women attending a joint obstetric–cardiology clinic at a tertiary maternity centre in a 12-month period of 2015–2016 compared with 2018–2019. This reflected the timing of the introduction of a multidisciplinary meeting prior to clinics and assessed the impact on referrals with the introduction of the European Society of Cardiology guidelines.

Data were reviewed from 56 and 67 patients in respective audit periods. Patient’s risk was stratified using modified World Health Organization classification.

Less than 50% of women with pre-existing cardiac conditions had received pre-conceptual counselling, although half of them had risks clearly documented. The majority of patients had a recent electrocardiograph and echocardiogram performed prior to counselling, and there was a modest improvement in the number of appropriate functional tests performed between time points. One-third of patients in both cohorts were taking cardiac medications during pregnancy.

There was a significant increase in the number of pregnant women with cardiac disease and in complexity according to modified World Health Organization risk classification. While there have been improvements, it is clear that further work to improve availability and documentation of pre-pregnancy counselling is needed.

Type
Original Article
Copyright
© The Author(s), 2021. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Knight, M, Bunch, K, Tuffnell, D, Shakespeare, J, Kotnis, R, Kenyon, S, Kurinczuk, JJ (Eds.) on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care – Lessons learned to inform maternity care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2015–17. National Perinatal Epidemiology Unit, University of Oxford, Oxford, 2019.Google Scholar
Buber, J, Valente, AM Predicting survival in adults with congenital heart disease: what are the odds? Heart 2018; 104: 16431644.10.1136/heartjnl-2018-312975CrossRefGoogle ScholarPubMed
European Society of Cardiology. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy. Eur Heart J 2018; 39: 31653241.10.1093/eurheartj/ehy340CrossRefGoogle Scholar
Janion-Sadawska, A, Sadowski, M, Zandecki, L, Kurzawaski, J, Polewczyk, A, Janion, M Pregnancy after myocardial infarction and coronary artery bypass grafting – is it safe? Postepy Kardiol INterwencyjnej 2014; 10: 2931.Google Scholar
Lu, C-W, Wu, M-H, Wang, J-K, et al. Preconception counselling for women with congenital heart disease. Acta Cardiol Sin 2015; 31: 500506.Google ScholarPubMed
Sanghavi, M, Rutherford, JD Cardiovascular physiology of pregnancy. Circulation 2014; 130: 10031008.CrossRefGoogle ScholarPubMed
Drenthen, W, Pieper, PG, Roos-Hesselink, JW, et al. Outcome of pregnancy in women with congenital heart disease: a literature review. J Am Coll Cardiol 2007; 49: 23032311.CrossRefGoogle ScholarPubMed
Drenthen, W, Boersma, E, Balci, A, Moons, P, Roos-Hesselink, JW, Mulder, BJ Predictors of pregnancy complications in women with congenital heart disease. Eur Heart J 2010; 31: 21242132.CrossRefGoogle ScholarPubMed
Rakusan, K Drugs in pregnancy: implications for a cardiologist. Exp Clin Cardiol 2010; 15: e100103.Google ScholarPubMed
Clapp, MA, Bernstein, SN Preconception counseling for women with cardiac disease. Curr Treat Options Cardiovasc Med 2017; 19: 67.CrossRefGoogle ScholarPubMed
ACOG Committee on Practice Bulletins. ACOG practice bulletin: clinical management guidelines for obstetrician-gynaecologists. Number 44, July 2003. Obstet Gynecol 2003; 102: 203213.CrossRefGoogle Scholar
Ionescu-Ittu, R, Marelli, AJ, Mackie, AS, Pilote, L Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec. Canada. BMJ 2009; 338: b1673.CrossRefGoogle ScholarPubMed
Liu, S, Joseph, KS, Luo, W, et al. Effect of folic acid food fortification in Canada on congenital heart disease subtypes. Circulation 2016; 134: 647655.CrossRefGoogle Scholar
Roos-Hesselink, JW, Budts, W, Walker, F, et al. Organisation of care for pregnancy in patients with congenital heart disease. Heart 2017; 103: 18541859.10.1136/heartjnl-2017-311758CrossRefGoogle ScholarPubMed
Royal College of Obstetricians and Gynaecologists. Cardiac Disease and Pregnancy (Good Practice No. 13). Royal College of Obstetricians and Gynaecologists, London, 2011.Google Scholar
Silversides, CK, Grewal, J, Mason, J, et al. Pregnancy outcomes in women with heart disease: the CARPREG II study. J Am Coll Cardiol 2018; 71: 24192430.10.1016/j.jacc.2018.02.076CrossRefGoogle ScholarPubMed
Thorne, S, MacGregor, A, Nelson-Piercy, C Risks of contraception and pregnancy in heart disease. Heart 2006; 92: 15201525.10.1136/hrt.2006.095240CrossRefGoogle ScholarPubMed
Mehta, LS, Warnes, CA, Bradely, E, et al. Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association. Circulation 2020; 141: e884e903.CrossRefGoogle ScholarPubMed
Vigl, M, Kaemmerer, M, Seifert-Klauss, V, et al. Contraception in women with congenital heart disease. Am J Cardiol 2010; 106: 13171321.CrossRefGoogle ScholarPubMed
Khairy, P, Ionescu-Ittu, R, Mackie, AS, Abrahamowicz, M, Pilote, L, Marelli, AJ Changing mortality in congenital heart disease. J Am Coll Cardiol 2010; 56: 11491157.CrossRefGoogle ScholarPubMed
James, PR. The importance of pre-pregnancy counselling in cardiac disease. Br J Cardiol 2014; 21: 2228.Google Scholar
Cauldwell, M, Steer, PJ, Swan, L, et al. Pre-pregnancy counseling for women with heart disease: A prospective study. Int J Cardiol 2017; 240: 374378.CrossRefGoogle ScholarPubMed
Morgan, H, Nana, M, Kinnaird, T Preconception counselling for women on cardiovascular medications. Eur Heart J 2019; 40: 34363437.CrossRefGoogle ScholarPubMed
Ojukwu, O, Patel, D, Stephenson, J, Howden, B, Shawe, J General practitioners’ knowledge, attitudes and views of providing preconception care: a qualitative investigation. Ups J Med Sci 2016; 121: 256263.CrossRefGoogle ScholarPubMed
Kizirian, NV, Black, KI, Musgrave, L, Hespe, C, Gordon, A Understanding and provision of preconception care by general practitioners. Aust N Z J Obstet Gynaecol 2019; 59: 799804.10.1111/ajo.12962CrossRefGoogle ScholarPubMed
Cribbs, MG, Briston, DA, Zaidi, AN Current attitudes and clinical practice towards the care of pregnant women with underlying CHD: a paediatric cardiology perspective. Cardiol Young 2017; 27: 236242.CrossRefGoogle ScholarPubMed
Zuhlke, L, Acquah, L Pre-conception counselling for key cardiovascular conditions in Africa: optimising pregnancy outcomes. Cardiovasc J Afr 2016; 27: 7983.CrossRefGoogle ScholarPubMed
Nair, M, Kurinczuk, JJ, Knight, M Ethnic variations in severe maternal morbidity in the UK – a case control study. PLoS One 2014; 9: e95086.10.1371/journal.pone.0095086CrossRefGoogle ScholarPubMed
Nair, M, Knight, M, Kurinczuk, JJ Risk factors and newborn outcomes associated with maternal deaths in the UK from 2009 to 2013: a national case-control study. BJOG 2016; 123: 16541662.CrossRefGoogle ScholarPubMed
Higginbottom, GMA, Evans, C, Morgan, M, Bharj, KK, Eldridge, J, Hussain, B Experience of and access to maternity care in the UK by immigrant women: a narrative synthesis systematic review. BMJ Open 2019; 9: e029478.10.1136/bmjopen-2019-029478CrossRefGoogle ScholarPubMed
Ruys, TP, Maggioni, A, Johnson, MR, et al. Cardiac medication during pregnancy, data from the ROPAC. Int J Cardiol 2014; 177: 124128.CrossRefGoogle ScholarPubMed
Chor, J, Rankin, K, Harwood, B, Handler, A Unintended pregnancy and postpartum contraceptive use in women with and without chronic medical disease who experienced a live birth. Contraception 2011; 84: 5763.CrossRefGoogle ScholarPubMed
Lindley, KJ, Madden, T, Cahill, AG, Ludbrook, PA, Billadello, JJ Contraceptive use and unintended pregnancy in women with congenital heart disease. Obstet Gynecol 2015; 126: 363369.10.1097/AOG.0000000000000911CrossRefGoogle ScholarPubMed
van der Zee, B, de Beaufort, ID, Steegers, EA, Denktas, S Perception of preconception counselling among women planning a pregnancy: a qualitative study. Fam Pract 2013; 30: 341346.CrossRefGoogle Scholar
Allen, D, Hunter, MS, Wood, S, Beeson, T One Key Question®: first Things First in Reproductive Health. Matern Child Health J 2017; 21: 387392.10.1007/s10995-017-2283-2CrossRefGoogle ScholarPubMed
Chor, J, Oswald, L, Briller, J, Cowett, A, Peacock, N, Harwood, B Reproductive health experiences of women with cardiovascular disease. Contraception 86: 464469.10.1016/j.contraception.2012.02.013CrossRefGoogle Scholar
Dawson, AJ, Krastev, Y, Parsonage, WA, Peek, M, Lust, K, Sullivan, EA Experiences of women with cardiac disease in pregnancy: a systematic review and metasynthesis. BMJ Open 2018; 8: e022755.CrossRefGoogle ScholarPubMed
Kovacs, AH, Harrison, JL, Colman, JM, Sermer, M, Siu, SC, Silversides, CK Pregnancy and contraception in congenital heart disease: what women are not told. J Am Coll Cardiol 2008; 52: 577578.CrossRefGoogle Scholar
Miner, PD, Canobbio, MM, Pearson, DD, et al. Contraceptive practices of women with complex congenital heart disease. Am J Cardiol 2017; 119: 911915.CrossRefGoogle ScholarPubMed
Ngu, K, Hay, M, Menahem, S Perceptions and motivations of an Australian cohort of women with or without congenital heart disease proceeding to pregnancy. Int J Gynaecol Obstet 2014; 126: 252255.10.1016/j.ijgo.2014.03.032CrossRefGoogle ScholarPubMed
Mason, E, Chandra-Mouli, V, Baltag, V, Christiansen, C, Lassi, ZS, Bhutta, ZA Preconception care: advancing from “important to do and can be done” to “is being done and is making a difference”. Reprod Health 2014; 11 (Suppl 3): 58.CrossRefGoogle Scholar
World Health Organisation. Meeting to develop a global consensus on preconception care to reduce maternal and childhood mortality and morbidity. World Health Organisation, Geneva, 2012.Google Scholar
Bellanca, HK, Hunter, MS ONE KEY QUESTION®: preventative reproductive health is part of high quality primary care. Contraception 2013; 88: 36.CrossRefGoogle Scholar