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SARS-CoV-2 infection induced thyroid storm and heart failure in an adolescent girl

Part of: Infectious

Published online by Cambridge University Press:  18 October 2021

Bibhuti B. Das Open the ORCID record for Bibhuti B. Das [Opens in a new window] ,
Divya Shakti ,
Jyothsna Akam-Venkata ,
Obiageli Obi ,
Michael D. Weiland  and
William Moskowitz
Bibhuti B. Das*
Affiliation:
Department of Pediatrics, Children’s of Mississippi Heart Center, University of Mississippi Medical Center, Jackson, MS, USA
Divya Shakti
Affiliation:
Department of Pediatrics, Children’s of Mississippi Heart Center, University of Mississippi Medical Center, Jackson, MS, USA
Jyothsna Akam-Venkata
Affiliation:
Department of Pediatrics, Children’s of Mississippi Heart Center, University of Mississippi Medical Center, Jackson, MS, USA
Obiageli Obi
Affiliation:
Department of Pediatrics, Division of Endocrinology, University of Mississippi Medical Center, Jackson, MS, USA
Michael D. Weiland
Affiliation:
Department of Pediatrics, Children’s of Mississippi Heart Center, University of Mississippi Medical Center, Jackson, MS, USA
William Moskowitz
Affiliation:
Department of Pediatrics, Children’s of Mississippi Heart Center, University of Mississippi Medical Center, Jackson, MS, USA
*
Author for correspondence: B. B. Das, MD, FAAP, FACC, Department of Pediatrics, Division of Pediatric Cardiology, University of Mississippi Medical Center, Jackson, MS 39211, USA. Tel: 601-984-5250; Fax: 601-984-5283. E-mail: bdas@umc.edu
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Abstract

We report a case of thyroid storm precipitated by SARS-CoV-2 infection in an adolescent girl with a history of Graves disease and dilated cardiomyopathy. This case highlights that SARS-CoV-2 infection can potentially trigger a thyrotoxicosis crisis and acute decompensated heart failure in a patient with underlying thyroid disease and myocardial dysfunction even in the absence of multi-system inflammatory syndrome in children. We systematically reviewed the thyrotoxicosis cases with SARS-CoV-2 infection and described its impact on pre-existing dilated cardiomyopathy.

Keywords

SARS-CoV-2 infection in childrenthyroid stormgraves diseasedilated cardiomyopathy
Type
Brief Report
Information
Cardiology in the Young , Volume 32 , Issue 6 , June 2022 , pp. 988 - 992
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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