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Single leaflet reconstruction in paediatric aortic regurgitation using the Ozaki procedure

Part of: Surgery

Published online by Cambridge University Press:  02 August 2021

Tao Shi ,
Zhan Gao ,
Shoujun Li  and
Zhongdong Hua Open the ORCID record for Zhongdong Hua [Opens in a new window]
Tao Shi
Affiliation:
Pediatric Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Beijing, China
Zhan Gao
Affiliation:
Pediatric Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Beijing, China Department of Cardiovascular Surgery, Children’s Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China
Shoujun Li*
Affiliation:
Pediatric Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Beijing, China
Zhongdong Hua*
Affiliation:
Pediatric Cardiac Surgery Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Beijing, China
*
Author for correspondence: Zhongdong Hua, Shoujun Li, Pediatric Cardiac Surgery Center, Fuwai Hospital, No.167 North Lishi Road, Xicheng District, Beijing, 100037, China. Tel: +86(10)88396555; E-mails: clusterheadache@126.com; 785997611@qq.com
Author for correspondence: Zhongdong Hua, Shoujun Li, Pediatric Cardiac Surgery Center, Fuwai Hospital, No.167 North Lishi Road, Xicheng District, Beijing, 100037, China. Tel: +86(10)88396555; E-mails: clusterheadache@126.com; 785997611@qq.com
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Abstract

Objectives:

Aortic valve repair in children is still a challenge. The aim of this study was to analyse the surgical results of children with aortic regurgitation who underwent single leaflet reconstruction using the Ozaki procedure in our medical centre.

Methods:

A retrospective study was conducted of nine children with aortic regurgitation who received single leaflet reconstruction from May 2017 to September 2019. Paired t-tests and Wilcoxon signed rank tests were used to compare the data at different time points.

Results:

The median surgical age was 4.7 (3.5, 6.4) years. Eight patients were pre-operatively diagnosed with severe aortic regurgitation, while one had moderate regurgitation. The left ventricles were significantly enlarged, with an average z-score of 3.8. Single leaflet reconstruction was carried out using glutaraldehyde-treated autologous pericardium under the standard Ozaki procedure. The median follow-up was 22 (14, 33) months. There was no post-operative death or re-intervention. One patient had moderate or more aortic regurgitation during the follow-up. The average degree of aortic regurgitation was mild, and the average z-score of the left ventricle decreased to −0.2 in the last follow-up.

Conclusions:

Single leaflet reconstruction using the Ozaki procedure was an effective surgical method for treating children with aortic regurgitation in our centre with satisfactory short-term results.

Keywords

Paediatric aortic regurgitationsingle leaflet lesionOzaki proceduresingle leaflet reconstruction
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 5 , May 2022 , pp. 789 - 793
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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