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Screening and Analysis of SARS-CoV-2 Antibody Among Unvaccinated Blood Donors in Chongqing, China

Published online by Cambridge University Press:  03 May 2024

Yulin Jiang Open the ORCID record for Yulin Jiang [Opens in a new window] ,
Lijuan Huang ,
Hongmei Liao ,
Chenghui Luo ,
Chunhong Zhang  and
Wei Mao
Yulin Jiang
Affiliation:
Chongqing Blood Center, Chongqing, China
Lijuan Huang
Affiliation:
Wanzhou Blood Center of Chongqing, Chongqing, China
Hongmei Liao
Affiliation:
Chongqing Blood Center, Chongqing, China
Chenghui Luo
Affiliation:
Wanzhou Blood Center of Chongqing, Chongqing, China
Chunhong Zhang
Affiliation:
Chongqing Blood Center, Chongqing, China
Wei Mao*
Affiliation:
Chongqing Blood Center, Chongqing, China
*
Corresponding author: Wei Mao; Email: 13594164527@163.com
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Abstract

Objective:

To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody among unvaccinated voluntary blood donors in Chongqing, and to provide evidence for epidemic surveillance.

Methods:

A total of 10,208 voluntary blood donors from January 5 to January 20, 2021, in the Chongqing area were collected, and the SARS-CoV-2 immunoglobulin (Ig) G and IgM antibodies were detected by chemiluminescence, and the differences of antibody-positive rate in different gender, age, ABO blood group, and different risk areas were analyzed.

Results:

Among 10208 blood donors, 10 were found to be positive for SARS-COV-2 IgG antibody, giving a positivity rate of SARS-COV-2 IgG at 0.10%, and 29 were positive for SARS-CoV-2 IgM antibody, with a positivity rate of SARS-CoV-2 IgM at 0.28%. There was no statistical difference in the positive rate of antibody among different genders, ages, and ABO blood types, but it was related to the number of confirmed coronavirus disease 2019 (COVID-19) cases in each city.

Conclusions:

The SARS-CoV-2 seroprevalence rate in Chongqing was low and correlated with the number of confirmed COVID-19 cases.

Keywords

Chongqingblood donorSARS-CoV-2 antibodySARS-CoV-2 seroprevalencerisk
Type
Research Letters
Information
Disaster Medicine and Public Health Preparedness , Volume 18 , 2024 , e85
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of Society for Disaster Medicine and Public Health, Inc

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