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I.—On the Developmental Processes in Mammary Glands and other Epidermal Structures

Published online by Cambridge University Press:  06 July 2012

B. I. Balinsky
B. I. Balinsky
Affiliation:
Animal Breeding and Genetics Research Organization at the Institute of Animal Genetics, Edinburgh.
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Synopsis:

The early development of the mammary glands and of hair follicles in the mouse and the rabbit has been investigated by means of mitotic counts, by histochemical methods and by cultivation in vitro. In the first stage of the formation of both types of rudiment a thickening of the epidermis appears as a consequence of an aggregation of cells, not of a local elevation of the mitotic rate. During this stage alkaline phosphatase is absent from the cells and the content of ribose-nucleic acid reduced. Both these substances appear in higher concentrations later, and their relation to processes of growth and differentiation is discussed. Essentially similar phenomena are found in rudiments cultivated in vitro, which, however, frequently suffer a degeneration by a process of keratinisation.

Type
Research Article
Information
Earth and Environmental Science Transactions of The Royal Society of Edinburgh , Volume 62 , Issue 1 , 1952 , pp. 1 - 31
Copyright
Copyright © Royal Society of Edinburgh 1952

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References

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