Hostname: page-component-848d4c4894-nr4z6 Total loading time: 0 Render date: 2024-05-27T07:51:27.000Z Has data issue: false hasContentIssue false
  • English
  • Français

Antigens common to Types 1 and 2 poliomyelitis viruses

Published online by Cambridge University Press:  15 May 2009

Golda Selzer  and
K. Larsson
Golda Selzer
Affiliation:
C.S.I.R. and U.C.T. Virus Research Unit, Department of Pathology, University of Cape Town
K. Larsson
Affiliation:
C.S.I.R. and U.C.T. Virus Research Unit, Department of Pathology, University of Cape Town
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

During a recent epidemic of poliomyelitis three viruses isolated (one Type 1 and two Type 2) elicited both Type 1 and Type 2 CF and precipitating antibodies in the patients whilst only the homotypic neutralizing antibodies were present. These viruses inoculated into animals produced specific CF and neutralizing antibodies, but precipitating antibodies to both types were present in a significant number of animals. These findings suggest that certain polioviruses have complement-fixing and precipitating antigens common to both Type 1 and Type 2 viruses.

We would like to thank our colleagues in the Virus Research Unit for their helpful advice and criticism and Dr J. Hampton (Poliomyelitis Inst., Johannesburg) for the concentrated Type 1 poliovirus vaccine.

Type
Research Article
Information
Journal of Hygiene , Volume 59 , Issue 3 , September 1961 , pp. 349 - 355
Copyright
Copyright © Cambridge University Press 1961

References

Polson, A. & Hampton, J. (1957). Studies on poliomyelitis virus concentration and purification of the virus. J. Hyg., Camb., 55, 344.Google Scholar
Selzer, G. (1960). The use of new antigens in the complement-fixation test for acute poliomyelitis. J. Hyg., Camb., 58, 321.Google Scholar