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The effect of the addition of Bordetella parapertussis suspensions on the protective power of the pertussis component of diphtheria–tetanus–pertussis vaccines
Published online by Cambridge University Press: 15 May 2009
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The addition of a parapertussis component to diphtheria–tetanus–pertussis vaccine reduces the agglutinogenic potency of the pertussis component in mice. The loss is evident when the amount of the parapertussis component added is 25% of that of the pertussis component, while the influence of relatively lower amounts of parapertussis organisms is less striking.
The parapertussis component in these vaccines, amounting to 2–25% of the pertussis component, does not affect the protective power of the pertussis component in mice.
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References
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