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The labile antigens of Shigella dysenteriae Shiga

Published online by Cambridge University Press:  15 May 2009

M. Shelubsky  and
L. Olitzki
M. Shelubsky
Affiliation:
Department of Hygiene and Bacteriology, The Hebrew University, Jerusalem
L. Olitzki
Affiliation:
Department of Hygiene and Bacteriology, The Hebrew University, Jerusalem
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Our data suggest that there are four different thermolabile antigens in S. dysenteriae (Shiga) appearing in different combinations in the five variants described. These antigens are:

1. The agglutination-inhibiting factor ‘I’, found in variants 1 and 3, which is a typical surface antigen.

2. A precipitinogen, ‘N’, probably identical with the neurotoxin, found in variants 1, 2 and 5.

3. A labile precipitinogen, ‘A’, in the extracts of variants 1 and 2, occurring in the deeper layers of the bacterial cell.

4. An additional precipitinogen, ‘B’, found in extracts of variants 1, 2, 3 and 4. It differs from the other labile antigens as its combining- and immunizing-powers are not destroyed by heating at 100° C. for 2 hr.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 1 , March 1948 , pp. 65 - 69
Copyright
Copyright © Cambridge University Press 1948

References

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