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Sulphonamide compounds and acute rheumatism

Published online by Cambridge University Press:  15 May 2009

A. J. Glazebrook
Affiliation:
From the Departments of Clinical Medicine and Bacteriology, University of Edinburgh
Scott Thomson
Affiliation:
From the Departments of Clinical Medicine and Bacteriology, University of Edinburgh
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1. In a controlled experiment prontosil was used in the treatment of four cases of streptococcal tonsillitis. These cases subsequently developed acute rheumatism.

2. Two cases of otitis media and one case of streptococcal pneumonia, not in the controlled experiment, were treated with sulphonamide and sulphapyridine respectively. These cases developed rheumatism as a complication.

3. Haemolytic streptococci were recovered from twelve cases of respiratory tract infection which subsequently developed acute rheumatic fever.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1942

References

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