Hostname: page-component-848d4c4894-75dct Total loading time: 0 Render date: 2024-06-02T15:12:07.924Z Has data issue: false hasContentIssue false
  • English
  • Français

Familial factors influencing the consumption of anxiolytics and hypnotics by children and adolescents

Published online by Cambridge University Press:  16 April 2020

A. Pélissolo ,
D. Gourion ,
C. Notides ,
M. Bouvard ,
J.P. Lépine  and
M.C. Mouren-Siméoni
A. Pélissolo*
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
D. Gourion
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
C. Notides
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
M. Bouvard
Affiliation:
Service Universitaire de psychiatrie Infanto-Juvénile, Centre Hospitalier Charles Perrens, 121 rue de la Béchade, 33076Bordeaux, France
J.P. Lépine
Affiliation:
Department of Psychiatry, Hôpital Fernand-Widal, AP-HP, 200 rue du Faubourg Saint-Denis, F75010Paris, France
M.C. Mouren-Siméoni
Affiliation:
Service de Psychopathologie de l’Enfant et de l’Adolescent, Hôpital Robert-Debré, AP-HP, 48 bd Serrurier, 75019Paris, France
*
*Correspondence and reprints: Department of psychiatry, Hôpital Pitié-Salpêtrière, 75651 Paris cedex. E-mail address: antoine.pelissolo@psl.ap-hop-paris.fr (A. Pélissolo).
Get access

Abstract

Many hypotheses have been made to explain the high rate of benzodiazepine consumption in France, including a general cultural and/or familial tendency to use certain types of psychotropic drugs. This study explored the association between lifetime medication use by parents and their children. Two hundred and twenty-one young patients (158 boys and 63 girls) consulting at a child and adolescent psychiatry department, six to 16 years of age (mean = 9.7 years), were screened for lifetime use of psychotropic drugs using a structured interview. Parents were asked about their own consumption, as well as their children’s. Lifetime consumption rates (at least once) were 22.2% in boys and 20.6% in girls, and 19.6% in children less than 11 years old. Higher rates were found in patients with emotional disorders (anxiety disorders and depression). In parents, 45.1% of mothers and 24.1% of fathers reported using medications at least once. A significant association was found between child and parental medication use: 34.1% of children had positive lifetime consumption when their mothers also used medications at least once versus only 13.6% in other children (odds ratio = 3.31 [1.68–6.50]; P = 0.001). The most significant association was found between medication use by girls and their mothers (odds ratio = 12.1 [2.38–61.5];P = 0.003). These data point to the existence of a family pattern of psychotropic drug consumption, especially in females.

Keywords

anxiolyticbenzodiazepinehypnoticpharmaco-epidemiology
Type
Original article
Information
European Psychiatry , Volume 16 , Issue 1 , February 2001 , pp. 11 - 17
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS.

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Achenbach, T.M.Edelbrock, C.S.Manual for the Child Behavior Check-List and revised child behavior profile Burlington (VT): University of Vermont, Departement of psychiatry; 1983.Google Scholar
Choquet, M.Ledoux, S.Adolescents, enquête nationale Paris: Editions INSERM; 1994.Google Scholar
Fombonne, E.Chehdan, F.Carradec, A.M.Achard, S.Navarro, N.Reis, S.Le Child Behavior Check-list: un instrument pour la recherche en psychiatrie de l’enfant Psychiatr Psychobiol 1988; 3: 409–418.Google Scholar
Gadow, K.D.An overview of three decades of research in pediatric psychopharmacoepidemiology J Child Adolesc Psychopharmacol 1997; 7: 219–236.CrossRefGoogle Scholar
Hong, S.H.Shepherd, M.D.P.sychosocial and demographic predictors of pediatric psychotropic medication use Am J Health Syst Pharm 1996; 15: 1934–1939.Google Scholar
Howie, J.G.Bigg, A.R.Family trends in psychotropic and antibiotic prescribing in general practice Br Med J 1980; 280: 836–838.Google Scholar
Kelleher, K.J.Hooman, A.A.Larson, D.B.Prescription of psychotropics to children in office-based practice Am J Dis Child 1989; 143: 855–859.Google Scholar
Kendler, K.S.N.Neale, M.C.Kessler, R.C.Heath, A.C.Eaves, L.J.The genetic epidemiology of phobias in women. The interrelationship of agoraphobia, social phobia, situational phobia, and simple phobia Arch Gen Psychiatry 1992; 49: 273–281.Google Scholar
Kopferschmitt, J.Meyer, P.Jaeger, A.Mantz, J.M.Roos, M.Troubles du sommeil et consommation de médicaments psychotropes chez l’enfant de 6 ans Rev Epidemiol Sante Publique 1992; 40: 467–471.Google Scholar
Lapeyre-Mestre, M.Lebret-Bories, E.Charlet, J.P.Montastruc, P.Consommation de médicaments dans une population d’âge scolaire Thérapie 1991; 46: 49–53.Google Scholar
Ledoux, S.Choquet, M.Manfredi, R.Self-reported use of drugs for sleep or distress among French adolescents J Adolesc Health 1994; 15: 495–502.Google ScholarPubMed
Legrain, M.Lecomte, T.Psychotropic drug consumption in France and several European countries Bull Acad Natl M 1997; 181: 1073–1084.Google Scholar
Lépine, J.P.Pélissolo, A.Epidemiology, comorbidity, and genetics of panic disorderNutt, D.JBallenger, J.CLépine, J.PPanic disorder. Clinical diagnosis, management and mechanisms London: Martine Dunitz Ltd; 1999. p. 9–23.Google Scholar
Minde, K.The use of psychotropic medication in preschoolers: some recent developments Can J Psychiatry 1998; 43: 571–575.Google Scholar
Pélissolo, A.Boyer, P.Lépine, J.P.Bisserbe, J.C.Epidemiology of the use of anxiolytic and hypnotic drugs in France and in the world Encephale 1996; 22: 187–196.Google Scholar
Pélissolo, A.Lecendreux, M.Mouren-Siméoni, M.C.Utilisation des hypnotiques chez l’enfant: description et analyse Arch Pédiatrie 1999; 6: 625–630.Google Scholar
Ray, W.A.Schaffner, W.Federspiel, C.F.Differences between female and male children in the receipt of prescribed psychotropic and controlled-analgesic drugs. A five-year epidemiologic study Med Care 1986; 24: 801–813.Google Scholar
Rylance, G.W.Woods, C.G.Cullen, M.E.Use of drugs by children BMJ 1988; 297: 445–447.Google Scholar
Sanz, E.J.Drug use in non-hospitalized children Pharm World Sci 1992; 14: 1–8.Google Scholar
Silove, D.Manicavasagar, V.O’Connell, D.Morris-Yates, A.Genetic factors in early separation anxiety: implications for the genesis of adult anxiety disorders Acta Psychiatr Scand 1995; 92: 17–24.Google Scholar
Wayne, A.R.Schaffner, W.Federspiel, C.F.Differences between female and male children in the receipt of prescribed psychotropic and controlled-analgesic drugs Med Care 1986; 24: 801–813.Google Scholar
Zito, J.M.Safer, D.J.dosReis, S.Gardner, J.F.Boles, M.Lynch, F.Trends in the prescribing of psychotropic medications to preschoolers JAMA 2000; 283: 1025–1030.Google Scholar
Submit a response

Comments

No Comments have been published for this article.