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Immunological changes in a case of Marchiafava Bignami disease: response to amineptine treatment

Published online by Cambridge University Press:  16 April 2020

T Humbert ,
JP Bureau  and
P Chabrand
T Humbert
Affiliation:
Service de Psychiatrie, Hôpital d'Alès, 30100 Alés en Cévennes, France
JP Bureau
Affiliation:
Laboratoire de Biologie Cellulaire et d'Immunogénétique, Faculté de Médecine, 34000Montpellier, France
P Chabrand
Affiliation:
Service de Psychiatrie, Hôpital de Nîmes, 30000Nîmes, France
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Summary

Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. We describe a regressive form of MBD in which a primary decrease in CD4+ cells was improved by amineptine treatment. No significant change in the CD4 : CDS ratio was observed in a few major depressed subjects receiving this drug.

Keywords

Marchiafava-Bignami diseaseCD4+ CD8+ T cells HLA typingamineptine
Type
Case report
Information
European Psychiatry , Volume 10 , Issue 2 , 1995 , pp. 107 - 109
Copyright
Copyright © Elsevier, Paris 1995

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