Evidence has been accumulating for association between PD and addiction in case report, retrospective and epidemiological study but generally focused on only one substance/behaviour and without taking any comparison group. The central question is PD patients are they prone to addictive behaviours more than general population do?

A cross-sectional, self questionnaire-based study was undertaken. The self-report (AUDIT, Fagerström, TDAS, SOGS…) explored addictions with substance (alcohol, tobacco…) or without (gambling, sex) in PD patients and healthy controls, mood disorders were also evaluated.

After screening full filed questionnaire and appropriate age- and sex-matched controls, we obtained 115 patients and controls. Dopamine dysregulation syndrome (DDS) is described in the total PD patients population (n=139).

We found a higher prevalence of smokers and positive for harmful drinking or alcohol dependence in the control group than in PD patients (2.6% smokers, 6.4% for alcohol). There is more over no significant differences between the two groups concerning gamblers prevalence. Pathologic hypersexuality prevalence is 1.8% in PD group (no case in controls) and 11.5% for DDS. Anxiety disorders in PD patients with DDS are more frequent than in PD patients without and 3 patients develop another addiction besides DDS.

Compared with general population and against all expectations HS and PG prevalence seems not to differ. However, the DDS seems to be a frequent syndrome which draws our attention to better screen this problem, especially taking into account the fact that anxiety appears to be closely link to it.