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Psychiatric comorbidity in epilepsy and difficulties in treatment: A case report

Published online by Cambridge University Press:  01 September 2022

M. Fernández Fariña ,
F. Mayor Sanabria ,
C. Regueiro Martín-Albo ,
M.E. Expósito Durán  and
A. Francos Ajona
M. Fernández Fariña*
Affiliation:
Hospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, Spain
F. Mayor Sanabria
Affiliation:
Hospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, Spain
C. Regueiro Martín-Albo
Affiliation:
Hospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, Spain
M.E. Expósito Durán
Affiliation:
Hospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, Spain
A. Francos Ajona
Affiliation:
Hospital Clínico San Carlos, Instituto De Psiquiatría Y Salud Mental, Madrid, Spain
*
*Corresponding author.

Abstract

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Introduction

We present the case of a 36-year-old male with depressive states, impulsive traits and fits of anger (including episodes of self and heteroagressiveness) since early childhood, in the context of traumatic family history and the beginning of an epileptic disease. These symptoms have been maintained over the years, in addition to other variable and recurrent symptoms, such as severe anxiety, somatizations or serious depressive symptoms.

Objectives

To highlight the possible influence of epilepsy in the course of mental illnesses, especially depression, as well as the increased difficulty in management.

Methods

We collected the complete medical history of a patient with an important history of mental health in addition to epileptic disease since childhood and we carried out a review of the comorbidity between these diseases and their treatment.

Results

The epileptic disease of our patient may have influenced the behavioural alterations and the depressive symptoms since childhood, as well as the personality traits with aggressiveness and impulsiveness. There is an added difficulty in treating this case given the possible interactions between antiepileptic and antidepressant medications.

Conclusions

This case highlights the importance of taking into account the influence of this comorbidity on the prognosis of patients. Knowing the interactions and side effects of drugs is essential for good clinical management.

Disclosure

No significant relationships.

Keywords

epilepsycomorbidityDepressionImpulsivity
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S462
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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