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Lactobacillus bloodstream infections genetically related to probiotic use in pediatric hematopoietic cell transplant patients

Published online by Cambridge University Press:  28 February 2022

Craig H. Gilliam ,
Jessica Brazelton de Cardenas ,
Delia Carias ,
Gaby Maron Alfaro ,
Randall T. Hayden  and
Hana Hakim Open the ORCID record for Hana Hakim [Opens in a new window]
Craig H. Gilliam
Affiliation:
Department of Infection Prevention and Control, St. Jude Children’s Research Hospital, Memphis, Tennessee
Jessica Brazelton de Cardenas
Affiliation:
Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee
Delia Carias
Affiliation:
Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee
Gaby Maron Alfaro
Affiliation:
Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee
Randall T. Hayden
Affiliation:
Department of Pathology, St. Jude Children’s Research Hospital, Memphis, Tennessee
Hana Hakim*
Affiliation:
Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee
*
Author for correspondence: Hana Hakim, E-mail: Hana.Hakim@stjude.org
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Abstract

We describe a cluster of 6 pediatric hematopoietic cell transplant recipients with Lactobacillus bacteremia attributed to probiotic use. Lactobacillus isolates cultured from probiotics and patients’ blood were proven to be related using whole-genome sequencing. Clinical studies are needed to evaluate the safety of probiotic use in immunocompromised patients.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , Volume 44 , Issue 3 , March 2023 , pp. 484 - 487
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Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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