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Effect of stage of lactation on transport of colloidal carbon or Staphylococcus aureus from the mammary gland lumen to lymph nodes in guinea pigs

Published online by Cambridge University Press:  01 June 2009

Daniel I. Schenkman ,
David T. Berman  and
Brian S. Yandell
Daniel I. Schenkman
Affiliation:
Department of Veterinary Science
David T. Berman
Affiliation:
Department of Veterinary Science
Brian S. Yandell
Affiliation:
Departments of Statistics and Horticulture, University of Wisconsin-Madison, Madison, WI 53706, USA
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Summary

Guinea pig mammary glands which were either lactating, involuting or dry were infused with colloidal carbon or killed staphylococci. At different time intervals following infusion, animals were killed and the superficial inguinal lymph nodes examined for the presence of carbon. Sides which had nodes with visible carbon were designated ‘positive’. The time intervals from infusion to positive for the three groups were compared using logistic regression. The times required for 50 % of the sides to be positive were estimated to be ˜4 h for lactating glands, 32 h for those in involution, and 13 min for dry glands. Histological differences in distribution of carbon in the mammary tissue suggest that differences in transit time may have been due to different mechanisms of transport through the glands in the three different physiological states. The distribution of bacteria was similar to that of the carbon in the corresponding tissues.

Type
Original Articles
Information
Journal of Dairy Research , Volume 52 , Issue 4 , November 1985 , pp. 491 - 500
Copyright
Copyright © Proprietors of Journal of Dairy Research 1985

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