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The ability of single sex infections of Schistosoma japonicum to induce resistance to reinfection in mice

Published online by Cambridge University Press:  05 June 2009

N. A. Moloney ,
P. Hinchcliffe  and
G. Webbe
N. A. Moloney
Affiliation:
The ability of single sex infections of Schistosoma japonicum to induce resistance to reinfection in mice
P. Hinchcliffe
Affiliation:
The ability of single sex infections of Schistosoma japonicum to induce resistance to reinfection in mice
G. Webbe
Affiliation:
The ability of single sex infections of Schistosoma japonicum to induce resistance to reinfection in mice
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Abstract

In four experiments, mice harbouring an average 50, 76 or over 200 Schistosoma japonicum female worms were not resistant when challenged six to eight weeks after infection. The female worms from these single sex infections were stunted and immature (average length 4–6 mm) and induced no overt pathology in the host. Male worm burdens of 60, 135 or 140 also induced little or no resistance to challenge in the host. The males from these single sex infections were fully grown for their age (average length 9 mm) and burdens of 135 or 140 induced distended hepatic portal veins and marked deposition of pigment in the livers of infected mice.

Keywords

Schistosoma japonicummouseresistancesingle sex infections
Type
Research Article
Information
Journal of Helminthology , Volume 60 , Issue 3 , September 1986 , pp. 250 - 254
Copyright
Copyright © Cambridge University Press 1986

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