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Co-occurrence of swine cysticercosis due to Taenia solium and Taenia hydatigena in ethnic minority villages at the Thai–Myanmar border

Published online by Cambridge University Press:  28 August 2018

K. Chaisiri Open the ORCID record for K. Chaisiri [Opens in a new window] ,
T. Kusolsuk ,
N. Homsuwan ,
S. Sanguankiat ,
P. Dekumyoy ,
G. Peunpipoom ,
S. Khiriphattharaphon ,
Y. Sako ,
T. Yanagida  and
M. Okamoto
...Show all authors
K. Chaisiri*
Affiliation:
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
T. Kusolsuk
Affiliation:
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
N. Homsuwan
Affiliation:
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
S. Sanguankiat
Affiliation:
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
P. Dekumyoy
Affiliation:
Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
G. Peunpipoom
Affiliation:
Tak Provincial Livestock Office, Tak Province, Thailand
S. Khiriphattharaphon
Affiliation:
Nong Bua Health Promoting Hospital, Tha Song Yang, Tak province, Thailand
Y. Sako
Affiliation:
Department of Parasitology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
T. Yanagida
Affiliation:
Laboratory of Parasitology, Joint Faculty of Veterinary Medicine, Yamaguchi University, Yamaguchi, Japan
M. Okamoto
Affiliation:
Section of Wildlife Diversity, Center for Human Evolution Modeling Research, Primate Research Institute, Kyoto University, Inuyama, Aichi, Japan
A. Ito*
Affiliation:
Department of Parasitology, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
*
Author for correspondence: K. Chaisiri, E-mail: kittipong.cha@mahidol.ac.th A. Ito, E-mail: akiraito@asahikawa-med.ac.jp
Author for correspondence: K. Chaisiri, E-mail: kittipong.cha@mahidol.ac.th A. Ito, E-mail: akiraito@asahikawa-med.ac.jp
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Abstract

As part of the international joint projects working towards the control of taeniosis/cysticercosis in Asia Pacific, epidemiological studies on Taenia solium cysticercosis have been carried out in high-incidence populations, such as minority groups in Thailand. To assess the epidemiology of cysticercotic infections in pigs in the hill-tribe minority villages (Karen) in Tak province, Thailand, we conducted serological screening and necropsies. The patterns of antibody response to T. solium antigens were then investigated using immunoblot assays. Of the 188 pig serum samples tested for antibody responses to partially purified low-molecular-weight antigens of T. solium cyst fluid, positive responses were detected in 37 samples (19.7%). Based on these results, 16 pigs (10 seropositive and 6 seronegative) were necropsied for investigation of cysticerci and intestinal parasites. All seropositive pigs were coinfected with both T. solium and Taenia hydatigena cysticerci, except one, which was infected with T. hydatigena alone. Three of the six seronegative pigs were confirmed to be infected with T. hydatigena. Pigs infected with T. solium showed much stronger antibody responses than those infected with T. hydatigena. Our results demonstrate the co-occurrence of two swine cysticercoses due to T. solium and T. hydatigena in the studied areas. This study also reveals the importance of direct confirmation of the presence of cysticerci by necropsy after serological screening. In addition to the prevalence of swine cysticercosis in these endemic areas, our findings also reveal potential implications for the development of serological diagnostic assays for swine cysticercosis.

Keywords

cysticercosisnecropsypigsserologyTaenia soliumTaenia hydatigenaThailand
Type
Research Paper
Information
Journal of Helminthology , Volume 93 , Issue 6 , November 2019 , pp. 681 - 689
Copyright
Copyright © Cambridge University Press 2018 

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Footnotes

*

Contributed equally to preparation of the manuscript.

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