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Evidence for increased susceptibility of Brugia pahangi-infected jirds (Meriones unguiculatus) to subsequent homologous infections

Published online by Cambridge University Press:  05 June 2009

Thomas R. Klei ,
John W. McCall  and
John B. Malone
Thomas R. Klei
Affiliation:
Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
John W. McCall
Affiliation:
Department of Parasitology, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA
John B. Malone
Affiliation:
Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA
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Abstract

The effect of existing Brugia pahangi infections on the establishment of a subsequent population was studied using jirds which had pre-challenge infections of 4 and 8 months duration. Necropsies were performed 28 days post-challenge inoculation in order to separate challenge and initial worm populations. The results indicate that existing infections of 4 or 8 months duration increase the susceptibility to subsequent homologous infections. The location of challenge population worms in tissue sites examined did not differ significantly between previously infected and uninfected groups. Previous infections did not affect the early growth of challenge population worms as indicated by their length.

Type
Research Papers
Information
Journal of Helminthology , Volume 54 , Issue 3 , September 1980 , pp. 161 - 166
Copyright
Copyright © Cambridge University Press 1980

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