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Seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran: a descriptive cross-sectional study

Published online by Cambridge University Press:  12 July 2021

P. Varzegar ,
M. Bayani ,
N. Kalantari ,
M. Nasiri-kenari ,
B. Amini Navaie ,
A. Mollalo  and
A. Rostami Open the ORCID record for A. Rostami [Opens in a new window]
P. Varzegar
Affiliation:
Student Research Committee, Babol University of Medical Science, Babol, Iran
M. Bayani*
Affiliation:
Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
N. Kalantari
Affiliation:
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
M. Nasiri-kenari
Affiliation:
North Research Center of Pasteur Institute of Iran, Amol, Iran
B. Amini Navaie
Affiliation:
North Research Center of Pasteur Institute of Iran, Amol, Iran
A. Mollalo
Affiliation:
Department of Public Health and Prevention Science, School of Health Sciences, Baldwin Wallace University, Berea, OH, USA
A. Rostami*
Affiliation:
Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
*
Author for correspondence: M. Bayani, E-mail: m_baiany@yahoo.com A. Rostami, E-mail: alirostami1984@gmail.com
Author for correspondence: M. Bayani, E-mail: m_baiany@yahoo.com A. Rostami, E-mail: alirostami1984@gmail.com
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Abstract

Strongyloidiasis and leptospirosis are neglected tropical diseases that have affected many countries across the world. In this study, we evaluated the seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran. We evaluated 156 laboratory- or clinically confirmed leptospirosis cases. The overall seroprevalence of S. stercoralis was 32.0% (95% confidence interval (CI): 27.4–36.5%, 50/156). Seropositivity was significantly associated with agricultural activities (odds ratio (OR): 2.84, 95% CI: 1.0–8.77) and gastrointestinal disorders (OR: 2.4, 95% CI: 1.1–4.9). Laboratory findings indicated that seropositivity of S. stercoralis was significantly associated with decreased levels of platelet and elevated levels of creatinine, alanine aminotransferase and aspartate aminotransferase (P < 0.05). Our findings suggested a higher exposure to S. stercoralis larvae among patients with leptospirosis. The public health and medical communities may benefit from this research through preventive measures to improve farmers’ knowledge and awareness regarding strongyloidiasis and leptospirosis and the associated risk factors.

Keywords

StrongyloidiasisleptospirosisseroprevalenceIran
Type
Short Communication
Information
Journal of Helminthology , Volume 95 , 2021 , e34
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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