Hostname: page-component-848d4c4894-r5zm4 Total loading time: 0 Render date: 2024-06-17T23:38:20.740Z Has data issue: false hasContentIssue false
  • English
  • Français

Studies with Brugia pahangi. 15. Cobalt 60 irradiation of the worm

Published online by Cambridge University Press:  05 June 2009

Pakeer Oothuman ,
D. A. Denham ,
P. B. McGreevy  and
G. S. Nelson
Pakeer Oothuman
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
D. A. Denham
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
P. B. McGreevy
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
G. S. Nelson
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, England
Get access Rights & Permissions [Opens in a new window]

Abstract

Infective larvae of Brugia pahangi were irradiated at 10, 25 or 45 krads by means of a Cobalt 60 source. In cats, 10 krads caused the worms to be stunted and sterile but allowed them to become 5th stage, migrate posterioly into the afferent lymphatic, and produce pathology.

25 krads prevented the worms from developing beyond the early fourth stage and from migrating away from the popliteal lymph node. No gross pathological reactions were evident. 45 krads produced the same effects as 25 krads but the longevity of the worms was much reduced.

Type
Research Papers
Information
Journal of Helminthology , Volume 52 , Issue 2 , June 1978 , pp. 121 - 126
Copyright
Copyright © Cambridge University Press 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Denham, D. A., Ponnudurai, T., Nelson, G. S., Guy, F. and Rogers, R. (1972) Studies with Brugia pahangi. I. Parasitological observations on primary infections of cats (Felis catus). International Journal for Parasitology, 2, 239–247.CrossRefGoogle ScholarPubMed
Ewert, A. (1971) Distribution of developing and mature Brugia malayi in cats at various times after a single infection. Journal of Parasitology, 57, 1039–1042.CrossRefGoogle Scholar
Jarrett, W. F. H., Jennings, F. W., McIntyre, W. I. M., Mulligan, W., Sharp, N. C. C. and Urouhart, G. M. (1959) Immunological studies on Dictyocaulus viviparus infections in calves – double vaccination with irradiated larvae. American Journal of Veterinary Research, 20, 522–526.Google Scholar
Semrad, J. E. (1937) Effects of Roentgen radiation on trichinosis in the albino rat. American Journal of Roentgenology, 38, 470–477.Google Scholar