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Introducing ethanol ablation as a treatment for thyroid cysts in the emergency setting

Published online by Cambridge University Press:  17 August 2022

L Robb Open the ORCID record for L Robb [Opens in a new window] ,
S Y Hey ,
H Reid  and
I J Nixon
L Robb*
Affiliation:
Department of Plastic and Reconstructive Surgery, Ninewells Hospital, NHS Tayside, Dundee, Scotland, UK
S Y Hey
Affiliation:
Department of Otolaryngology, St John's Hospital at Howden, NHS Lothian, Livingston, Scotland, UK
H Reid
Affiliation:
Department of Radiology, St John's Hospital at Howden, NHS Lothian, Livingston, Scotland, UK
I J Nixon
Affiliation:
Department of Otolaryngology, St John's Hospital at Howden, NHS Lothian, Livingston, Scotland, UK
*
Author for correspondence: Ms Lydia Robb, Plastic Surgery Department, NHS Tayside, Ninewells Hospital, Dundee DD1 9SY, Scotland, UK E-mail: Lydia.robb@doctors.org.uk
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Abstract

Background

Ethanol ablation for the treatment of thyroid cysts has been well documented in the literature as a safe, effective treatment option in the elective setting. This study demonstrates the use of ethanol ablation in the emergency setting.

Methods

Three patients presenting with airway-threatening compressive symptoms secondary to a thyroid cyst were treated with ethanol ablation within 24 hours of presentation to hospital.

Results

All patients had symptom resolution at a median of nine months follow up post procedure. Sixty-six per cent of patients required only one treatment. There was a median of 100 per cent radiological resolution of the cystic component. The median Glasgow Benefit Inventory score was +27.7, similar to that for tonsillectomy.

Conclusion

Ethanol ablation is a safe, cost-effective and efficient treatment option for thyroid cysts in the acute setting.

Keywords

OtolaryngologyThyroid DiseasesAblation Techniques
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 137 , Issue 4 , April 2023 , pp. 467 - 470
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Ms L Robb takes responsibility for the integrity of the content of the paper

References

Paschke, R, Hegedüs, L, Alexander, E, Valcavi, R, Papini, E, Gharib, H. Thyroid nodule guidelines: agreement, disagreement and need for future research. Nat Rev Endocrinol 2011;7:354–6110.1038/nrendo.2011.1CrossRefGoogle ScholarPubMed
Papini, E, Pacella, CM. Diagnosis of endocrine disease: thyroid ultrasound (US) and US-assisted procedure: from shadows into an array of applications. Eur J Endocrinol 2014;170:133–4610.1530/EJE-13-0917CrossRefGoogle ScholarPubMed
Hegedüs, L, Frasoldati, A, Negro, R, Papini, E. European Thyroid Association survey on use of minimally invasive techniques for thyroid nodules. Eur Thyroid J 2020;9:194–20410.1159/000506513CrossRefGoogle ScholarPubMed
Papini, E, Pacella, CM, Solbiati, LA, Achille, G, Barbaro, D, Bernardi, S et al. Minimally-invasive treatments for benign thyroid nodules: a Delphi-based consensus statement from the Italian minimally-invasive treatments of the thyroid (MITT) group. Int J Hyperthermia 2019;36:376–8210.1080/02656736.2019.1575482CrossRefGoogle ScholarPubMed
Nixon, IJ, Angelos, P, Shaha, AR, Rinaldo, A, Williams, MD, Ferlito, A. Image-guided chemical and thermal ablations for thyroid disease: review of efficacy and complications. Head Neck 2018;40:2103–1510.1002/hed.25181CrossRefGoogle ScholarPubMed
National Institute for Health and Care Excellence. Thyroid Disease: Assessment and Management. NICE Guideline 145 [NG145]. London: NICE, 2019;53–5Google Scholar
Hahn, SY, Shin, JH, Na, DG, Ha, EJ, Ahn, HS, Lim, HK et al. Ethanol ablation of the thyroid nodules: 2018 consensus statement by the Korean Society of Thyroid Radiology. Korean J Radiol 2018;20:609–2010.3348/kjr.2018.0696CrossRefGoogle Scholar
Del Prete, S, Caraglia, M, Russo, D. Percutaneous ethanol injection efficacy in the treatment of large symptomatic thyroid cystic nodules: ten-year follow-up of a large series. Thyroid 2002;12:815–2110.1089/105072502760339398CrossRefGoogle ScholarPubMed
Suh, CH, Baek, JH. Ethanol ablation of predominantly cystic thyroid nodules: evaluation of recurrence rate and factors related to recurrence. Clin Radiol 2015;70:42–710.1016/j.crad.2014.09.008CrossRefGoogle ScholarPubMed
Bennedbaek, F, Hegedüs, L. Treatment of recurrent thyroid cysts with ethanol: a randomized double-blind controlled trial. J Clin Endocrinol Metab 2003;88:5773–710.1210/jc.2003-031000CrossRefGoogle ScholarPubMed
Sung, JY, Baek, JH, Kim, KS, Lee, D, Yoo, H, Kim, JK et al. Single-session treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation: a prospective randomized study. Radiology 2013;269:293–30010.1148/radiol.13122134CrossRefGoogle ScholarPubMed
Hey, SY, Robb, L, Gammack, P, Smith, DA, Rodrigues, MA, Summers, D et al. Introducing an ethanol ablation service for recurrent symptomatic thyroid cysts within the NHS--a prospective study of twenty-six patients. Clin Otolaryngol 2021;46:645–910.1111/coa.13697CrossRefGoogle ScholarPubMed
Jang, S, Baek, J, Kim, J. How to manage the patients with unsatisfactory results after ethanol ablation for thyroid nodules: role of radiofrequency ablation. Eur J Radiol 2012;81:905–1010.1016/j.ejrad.2011.02.039CrossRefGoogle Scholar