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Survival outcomes after surgical resection of pulmonary metastases of head and neck tumours

Published online by Cambridge University Press:  03 February 2016

S Hosokawa ,
K Funai ,
K Sugiyama ,
G Takahashi ,
J Okamura ,
Y Takizawa ,
T Yamatodani  and
H Mineta
S Hosokawa*
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
K Funai
Affiliation:
First Department of Surgery, Hamamatsu University School of Medicine, Japan
K Sugiyama
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
G Takahashi
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
J Okamura
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
Y Takizawa
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
T Yamatodani
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
H Mineta
Affiliation:
Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, Japan
*
Address for correspondence: Dr Seiji Hosokawa, Department of Otorhinolaryngology/Head and Neck Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka 431-3192, Japan Fax: +81 53 435 2253 E-mail: seijih1969@gmail.com
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Abstract

Background:

There is limited information available regarding the benefits and outcomes of resection of pulmonary metastases arising from head and neck cancers.

Methods:

A retrospective review was performed of 21 patients who underwent resection of pulmonary metastases of primary head and neck malignancies at Hamamatsu University Hospital. Clinical staging, treatment methods, pathological subtype (particularly squamous cell carcinoma), disease-free interval and overall survival were evaluated.

Results:

The 5- and 10-year overall survival rates of the study participants were 67.0 per cent and 55.0 per cent, respectively, as determined by the Kaplan–Meier method. The prognosis for patients with a disease-free interval of less than 24 months was poor compared to those with a disease-free interval of greater than 24 months (p = 0.0234).

Conclusion:

Patients with short disease-free intervals, and possibly those who are older than 60 years, should be categorised as having severe disease. However, pulmonary metastases from head and neck malignancies are potentially curable by surgical resection.

Keywords

Lung NeoplasmsNeoplasm MetastasisHead And Neck NeoplasmsSurvival Analysis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 130 , Issue 3 , March 2016 , pp. 291 - 295
Copyright
Copyright © JLO (1984) Limited 2016 

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