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Topical nasal steroids in non-atopic perennial rhinitis; subjective symptom scores and objective measurement of nasal resistance by active anterior rhinomanometry

Published online by Cambridge University Press:  29 June 2007

N. S. Jones*
Affiliation:
Senior House officer Department of Otohinolaryngology. The Royal Surrey Country Hospital, Guildord, Surrey.
G. S. Kenyon
Affiliation:
Senior Registrar Department of Otohinolaryngology. The Royal Surrey Country Hospital, Guildord, Surrey.
*
Nicholas S. Jones, E.N.T. Department, Guy's Hospital, St Thomas Street, London SE1 9RT.

Abstract

We present a study of 22 patients with perennial non-atopic rhinitis who have been treated with a course of topical beclomethasone diproprionate (Beconase). All subjects were skin-test negative for the common inhaled allergens and had normal total and specific IgE levels. The results of treatment were assessed by symptom scoring and by active anterior rhinomanometry, and are compared to measurements of resistance made in 22 untreated controls and an equal number of normal volunteers.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1988

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References

Borum, P. (1978) Intranasal Ipratropium: Inhibition of methacholine induced hypersection. Rhinology, 16: 225233.Google Scholar
Broms, P., Johnson, B. and Lamm, C. T. (1981) Rhinomanometry: A system for numerical description of nasal airway resistance. Rhinology, 18: 7379.Google Scholar
Clement, P. A. R. (1984) Committee report on standardization of rhinomanometry. Rhinology, 22: 151155.Google Scholar
Gibson, G. J., Maberley, D. J., Lal, S., Ali, M. M. and Butler, A. G. (1974) Double-blind cross-over trial comparing intranasal Beclomethasone disproprtionate and placebo in perennial rhinitis. British Medical Journal, 4: 503504.Google Scholar
Incaudo, G., Schatz, M., Yamomoto, F., Mellan, M., Gepea, S. and Johnson, J. D. (1980) Intranasal flunisolide in the treatment of perennial rhinitis: Correlation with immunological parameters. Journal of Allergy and Clinical Immunology, 65:(1), 4149.Google Scholar
Jones, A. S. and Lancer, J. M. (1987) Vasomotor rhinitis. British Medical Journal, 1: 505506.CrossRefGoogle Scholar
Kenyon, G. S. (1987) Phase variation in nasal airways resistance assessed by active anterior rhinomanometry. Journal of Laryngology and Otology, 101: 910916.CrossRefGoogle ScholarPubMed
Knight, A. and Kolin, A. (1983) Long term efficacy and safety of beclomethasione diproprionate aerosol in perennial rhinitis. Annals of allergy, 50: 81–4.Google Scholar
Knight, A., Underdown, B. J., Connell, J. T., Nedzelski, J. and Elie, R. (1979) Immmunological parameters in perennial rhinitis. British Medical Journal, 1: 255.Google Scholar
Mullarkey, M. F., Hill, J. S. and Webb, D. F. (1980) Allergic and non-allergic rhinitis: Their characterization with attention to themeasuring of nasal eosinophilia. Journal of Allergy and Clinical Immunology, 65: (2). 122126.CrossRefGoogle Scholar
Mygind, N. (1979) Nasal Allergy. 2nd Ed.Blackwell, Oxford.Google Scholar
Mygind, N., Dirksen, A., Johnsen, N. J. and Weeke, B. (1978) Perennial rhinitis: An analysis of skin testing, serum IgE, and blood and smear eosinophilia in 201 patients. Clinical Otolarnygology, 3: 189196.Google Scholar
Pepys, J. (1973) Immunopathology of allergic lung disease. Clinical Allergy, 3: 122.Google Scholar
Tarlo, S. M., Cockroft, D. W., Dolovich, J. and Hargreave, F. E. (1977) Beclomethasone diproprionate aerosol in perennial rhinitis. Journal of Allergy and Clinical Immunology, 59: (3), 232236.CrossRefGoogle Scholar
Viner, A. S. and Jackman, N. (1976) Retrospective survey of 1271 patients diagnosed as perennial rhinitis. Clinical allergy, 6: 251259.Google Scholar