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Transoral laser microsurgery outcomes with early glottic cancer: the Dalhousie University experience

Published online by Cambridge University Press:  31 January 2011

S E Lester ,
M H Rigby  and
S M Taylor
S E Lester*
Affiliation:
Division of Otolaryngology Head and Neck Surgery, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
M H Rigby
Affiliation:
Division of Otolaryngology Head and Neck Surgery, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
S M Taylor
Affiliation:
Division of Otolaryngology Head and Neck Surgery, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
*
Address for correspondence: Mr Shane Lester, Consultant ENT Surgeon, Darlington Memorial Hospital, Darlington DL3 6HX, UK Fax: +44 (0)1325 743798 E-mail: shanelester@nhs.net
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Abstract

Objective:

To report the results of transoral laser microsurgery for the treatment of early glottic cancer at our institution.

Design:

Cohort study. Retrospective review of charts of patients diagnosed with tumour stage 1 or 2 (early stage; no nodes or metastases), previously untreated, primary glottic cancer, treated with transoral laser microsurgery at the Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada. The minimum follow-up period was two years.

Setting:

Tertiary care head and neck cancer centre.

Participants:

Fifty-three patients treated between January 2002 and November 2007.

Outcome measure:

Kaplan–Meier survival analysis for disease-free survival, overall survival and laryngectomy-free survival, at five years.

Results:

The group comprised 46 men and seven women, with a mean age of 66 years (range 30–84 years). Mean follow up was 40 months (range 12–89 months). There were four cases of complications (7.5 per cent). Kaplan–Meier survival analysis revealed a five-year disease-free survival (including salvage) of 96.2 per cent, a five-year overall survival (all causes) of 88.8 per cent and a five-year laryngectomy-free survival of 98.1 per cent.

Conclusion:

Transoral laser microsurgery is a safe and effective initial treatment for early laryngeal cancer, and has high rates of laryngeal preservation and disease-free survival.

Keywords

Laryngeal NeoplasmsCarcinomaLasersSurgery
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 5 , May 2011 , pp. 509 - 512
Copyright
Copyright © JLO (1984) Limited 2011

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