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A green and facile strategy for hierarchically porous poly(L-lactic acid)/poly(ε-caprolactone) monolithic composites

Published online by Cambridge University Press:  16 July 2019

Mingjing Chen ,
Juan Qiao ,
Xiaoxia Sun ,
Wenjuan Chen ,
Hiroshi Uyama  and
Xinhou Wang
Mingjing Chen
Affiliation:
Key Laboratory of Textile Science & Technology of Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
Juan Qiao
Affiliation:
Key Laboratory of Textile Science & Technology of Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
Xiaoxia Sun*
Affiliation:
Key Laboratory of Textile Science & Technology of Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
Wenjuan Chen
Affiliation:
Key Laboratory of Textile Science & Technology of Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
Hiroshi Uyama
Affiliation:
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan
Xinhou Wang
Affiliation:
Key Laboratory of Textile Science & Technology of Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
*
a)Address all correspondence to this author. e-mail: xxsun@dhu.edu.cn
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Abstract

Hierarchically porous poly(L-lactic acid) (PLLA)/poly(ε-caprolactone) (PCL) monolithic composites were fabricated by nonsolvent-induced phase separation (NIPS) method without any template for the first time. A homogeneous hierarchical porous structure with relatively large specific surface area containing both mesopores and macropores was confirmed by pore size distribution plots and scanning electron microscopy images, respectively. Fourier transform infrared analysis (FTIR) revealed that PLLA and PCL were physically blended. Differential scanning calorimeter (DSC) analysis further showed that the two components were physically blended but had a slight thermal compatibility. Meanwhile, X-ray diffraction (XRD) tests indicated that the addition of PCL hindered the crystallization of PLLA. Herein, the formation of the mesopores and macropores during the phase separation process was explained from the microscopic point of view according to the results of XRD and DSC. The present monolithic composites with hierarchically porous structures had promising prospect for applications of tissue engineering.

Keywords

porositypolymerphase transformation
Type
Article
Information
Journal of Materials Research , Volume 34 , Issue 17: Focus Issue: Building Advanced Materials via Particle Aggregation and Molecular Self-Assembly , 16 September 2019 , pp. 2990 - 2999
Copyright
Copyright © Materials Research Society 2019 

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