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Variation in applicator positions during interfraction high-dose rate brachytherapy in carcinoma cervix: dosimetric evaluation

Published online by Cambridge University Press:  23 April 2013

Kamlesh Passi ,
Lalit M. Aggarwal ,
Rajesh Vashistha ,
Bikramjit Singh ,
Parveen Kaur ,
Sureshchandra J. Gupta  and
Than S. Kehwar
Kamlesh Passi
Affiliation:
Department of Radiation Oncology, MD Oswal Cancer Hospital, Ludhiana (Pb), India
Lalit M. Aggarwal
Affiliation:
Department of Radiotherapy & Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi (UP), India
Rajesh Vashistha
Affiliation:
Department of Radiation Oncology, Max Superspeciality Hospital, Bathinda (Pb), India
Bikramjit Singh
Affiliation:
Department of Radiation Oncology, MD Oswal Cancer Hospital, Ludhiana (Pb), India
Parveen Kaur
Affiliation:
Department of Radiation Oncology, MD Oswal Cancer Hospital, Ludhiana (Pb), India
Sureshchandra J. Gupta
Affiliation:
Department of Physics, University of Mumbai (MH), India
Than S. Kehwar*
Affiliation:
Department of Radiation Oncology, UPMC Cancer Centers, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
*
Correspondence to: Than S. Kehwar, Professor of Radiology, Division of Radiation Oncology, Penn State Hershey Cancer Institute, Penn State Milton S. Hershey Medical Center, 500 University Dr., CH63, Hershey, PA 17033, USA. Tel: +717-531-1523. Fax: +717-531-0446. E-mail: drkehwar@gmail.com
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Abstract

Purpose

This study was designed to study the variations in different geometrical and dosimetric parameters.

Materials and methods

In this study, two groups comprises 21 and 28 patients, who were treated with 9·5 Gy × 2 Fx and 7·5 Gy × 3 Fx, respectively, using microselectron high-dose rate (HDR) remote control unit. All patients were analysed using orthogonal radiographs to evaluate variations in different parameters.

Results

Variations in different parameters are more in Group II patients than in Group I patients, which show that the variation in geometrical and dosimetrical parameters increases with increasing HDR number of fractions.

Conclusion

In the reporting of an outcome of multiple fractionation of HDR treatments resultant dosimetric parameters must be evaluated and must be used for clinical interpretation.

Keywords

carcinoma of cervixHDR brachytherapyICRU 38 report
Type
Original Articles
Information
Journal of Radiotherapy in Practice , Volume 12 , Issue 4 , December 2013 , pp. 305 - 317
Copyright
Copyright © Cambridge University Press 2013 

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