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Bioactive organic-inorganic hybrid aerogels

Published online by Cambridge University Press:  01 February 2011

Luis Esquivias ,
Víctor Morales-Flórez ,
Manuel Piñero ,
Nicolás de la Rosa-Fox ,
Julio Ramírez ,
José González-Calbet ,
Antonio Salinas  and
María Vallet-Regí
Luis Esquivias
Affiliation:
Departamento de Física de la Materia Condensada, Facultad de Ciencias, UCA. Puerto Real 11510. Cádiz, Spain.
Víctor Morales-Flórez
Affiliation:
Departamento de Física de la Materia Condensada, Facultad de Ciencias, UCA. Puerto Real 11510. Cádiz, Spain.
Manuel Piñero
Affiliation:
Departamento de Física Aplicada, CASEM, UCA
Nicolás de la Rosa-Fox
Affiliation:
Departamento de Física de la Materia Condensada, Facultad de Ciencias, UCA. Puerto Real 11510. Cádiz, Spain.
Julio Ramírez
Affiliation:
Departamento de Química Inorgánica. Facultad de Químicas. UCM.
José González-Calbet
Affiliation:
Departamento de Química Inorgánica. Facultad de Químicas. UCM.
Antonio Salinas
Affiliation:
Departamento de Química Inorgánica y Bioinorgánica. Facultad de Farmacia. UCM
María Vallet-Regí
Affiliation:
Departamento de Química Inorgánica y Bioinorgánica. Facultad de Farmacia. UCM
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Abstract

We have prepared organic-inorganic hybrid materials (OIHM), incorporating an organic phase in the inorganic precursor sol, using high power ultrasound for assistance with agitation. A sono-ormosil results after gelation. Colloidal silica particles have been added to these hybrids to enable network porous volume and pore radius to be tailored to specific requirements. Finally, in vitro bioactivity of this material has been promoted by adding calcium to the initial sol. The structure and bioactivity of these materials have been subjected to preliminary study, including their mechanical behaviour. These materials have a very fine structure especially after colloidal silica particles have been included. When immersed in a solution simulating blood plasma, they are bioactive, and the sample with colloid particles presents a better behaviour in vitro

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 847: Symposium EE – Organic/Inorganic Hybrid Materials , 2004 , EE12.1
Copyright
Copyright © Materials Research Society 2005

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References

REFERENCES

1. Hench, L. L. J. Am. Ceram. Soc. 81 (1998) 1705.Google Scholar
2. Kamitahara, M., Kawashita, M., Miyata, N., Kokubo, T. and Nakamura, T., J. Mat. Sci.: Mat. In Med. 13 (2002) 1015–1020 Google Scholar
3. Esquivias, L., Rodríguez-Ortega, J., Barrera-Solano, C. and de la Rosa-Fox, N., J. Non-Cryst-Solids, 225 (1998) 239–243.Google Scholar
4. Barret, E.P., Joyner, L.G., Halenda, P.P., J. Am. Chem Soc. 73, (1951) 373.Google Scholar
5. Kokubo, T.; Kushitani, H.; Sakka, S.; Kitsugi, T.; Yamamura, Y. J. Biomed. Mater. Res. 24 (1990), 721.Google Scholar
6. Porod, G., Kolloid Z., 124 83–114 (1951)Google Scholar
7. LeGeros, R. Z. Calcium phosphate in oral biology and medicine. In Monographs in Oral Science, Myers, H. M., Ed.; Karger: Zurich, 1991.Google Scholar
8. Elliot, J. C. Structure and Chemistry of the Apatites and other Calcium Orthophosphates, Studies in Inorganic Chemistry 18, Elsevier, Ed.; Amsterdam, 1994.Google Scholar
9. Vallet-Regí, M., J. Chem. Soc., Dalton Trans, 2001, 97.Google Scholar
10. Kokubo, T., An. Quim. Int. Ed. 1997 93, S49.Google Scholar