Hostname: page-component-848d4c4894-ttngx Total loading time: 0 Render date: 2024-06-01T06:07:59.329Z Has data issue: false hasContentIssue false
  • English
  • Français

An Affordable Insulin Pump for Type-1 Diabetic Patients: A Case Study of User-in-the-Loop Approach to Engineering Design

Part of: Design for Healthcare

Published online by Cambridge University Press:  26 July 2019

Deval Karia ,
Rohit S Nambiar  and
Manish Arora

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Continuous subcutaneous insulin infusion using an insulin pump has been documented to have significant clinical benefits as a treatment plan for type 1 diabetes mellitus patients. However, despite this, adoption in resource constrained settings like India is severely limited. This is often attributed to the costs associated with the device.

The usage of such a device is closely associated with a patient's lifestyle and its design demands a more user-centric approach to engineering design. The stakeholder involvement is needed for validation and guiding the product development direction. In this paper, we've outlined a user-in-the-loop approach to engineering design using the design of an insulin pump as a case study.

Keywords

Biomedical designUser centred designDesign processUser-in-the-loopInsulin pump
Type
Article
Information
Proceedings of the Design Society: International Conference on Engineering Design , Volume 1 , Issue 1 , July 2019 , pp. 847 - 856
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
© The Author(s) 2019

References

Battelino, T. (2006), “Risk and benefits of continuous subcutaneous insulin infusion (CSII) treatment in school children and adolescents”, Pediatric Diabetes, Vol. 7, pp. 20–24.Google Scholar
Chan, A., Breton, M.D. and Kovatchev, B.P. (2008), “Effects of pulsatile subcutaneous injections of insulin lispro on plasma insulin concentration levels”, Journal of Diabetes Science and Technology, Vol. 2 No. 5, pp. 844–852.Google Scholar
Chao, T.E., Lo, N.C., Mody, G.N. and Sinha, S.R. (2014), “Strategies for last mile implementation of global health technologies”, The Lancet Global Health, Vol. 2 No. 9, pp. e497–e498.Google Scholar
Chikofsky, E.J. and Cross, J.H. (1990), “Reverse engineering and design recovery: A taxonomy”, IEEE Software, Vol. 7 No. 1, pp. 13–17.Google Scholar
Davis, D.L., Hatch, R.F., Poirier, D.A. and Patient Solutions Inc (1998), “Method of measuring an occlusion in an infusion device with disposable elements”. U.S. Patent 5,803,712.Google Scholar
DelCastilio, J.A., Yardimci, A., Baxter Healthcare SA and Baxter International Inc (2011), “System and method for detecting occlusion using flow sensor output”. U.S. Patent 7,880,624.Google Scholar
Doyle, E.A., Weinzimer, S.A., Steffen, A.T., Ahern, J.A.H., Vincent, M. and Tamborlane, W.V. (2004), “A randomized, prospective trial comparing the efficacy of continuous subcutaneous insulin infusion with multiple daily injections using insulin glargine”, Diabetes Care, Vol. 27 No. 7, pp. 1554–1558.Google Scholar
Fricke, E., Gebhard, B., Negele, H. and Igenbergs, E. (2000), “Coping with changes: causes, findings, and strategies”, Systems Engineering, Vol. 3 No. 4, pp. 169–179.Google Scholar
Hirsch, I.B., Farkas-Hirsch, R. and Skyler, J.S. (1990), “Intensive insulin therapy for treatment of type I diabetes”, Diabetes Care, Vol. 13 No. 12, pp. 1265–1283.Google Scholar
Jagtap, S., Larsson, A., Hiort, V., Olander, E., Warell, A. and Khadilkar, P. (2014), “How design process for the base of the pyramid differs from that for the top of the pyramid”, Design Studies, Vol. 35 No. 5, pp. 527–558.Google Scholar
Kesavadev, J., Das, A.K., Unnikrishnan, R., Joshi, S.R., Ramachandran, A., Shamsudeen, J., Krishnan, G., Jothydev, S. and Mohan, V. (2010), “Use of insulin pumps in India: suggested guidelines based on experience and cultural differences”, Diabetes Technology & Therapeutics, Vol. 12 No. 10, pp. 823–831.Google Scholar
Klonoff, D.C., Freckmann, G. and Heinemann, L. (2017), Insulin pump occlusions: for patients who have been around the (infusion) block.Google Scholar
Mohan, V., Shyamsunder, R., Ramchandran, A., Snehalatha, C. and Viswanathan, M. (1983), “Experience with insulin pump treatment in Indian diabetics. A preliminary report”, The Journal of the Association of Physicians of India, Vol. 31 No. 11, pp. 715–717.Google Scholar
National Diabetes Services Scheme. (2018), “Continuous Glucose Monitoring”. [ONLINE] Available at: https://www.ndss.com.au/cgm. [Accessed October 2018]Google Scholar
Niezen, G., Eslambolchilar, P. and Thimbleby, H. (2016), “Open-source hardware for medical devices”, BMJ Innovations, Vol. 2 No. 2, pp. 78–83.Google Scholar
Norman, D.A. and Draper, S.W. (1986), User centered system design: New perspectives on human-computer interaction. CRC Press.Google Scholar
Nuxoll, E. (2013), “BioMEMS in drug delivery”, Advanced Drug Delivery Reviews, Vol. 65 No. 11–12, pp. 1611–1625.Google Scholar
Olsen, J.M. and Deltec Inc (1997), “Occlusion detection system for an infusion pump”. U.S. Patent 5,695,473.Google Scholar
Open Artificial Pancreas System. (2018), “What is #OpenAPS?”. [ONLINE] Available at: https://openaps.org. [Accessed January 2018]Google Scholar
Pahl, G. and Beitz, W. (2013), Engineering design: a systematic approach. Springer Science & Business Media.Google Scholar
Retnakaran, R., Hochman, J., DeVries, J.H., Hanaire-Broutin, H., Heine, R.J., Melki, V. and Zinman, B. (2004), “Continuous subcutaneous insulin infusion versus multiple daily injections: the impact of baseline A1c”, Diabetes Care, Vol. 27 No. 11, pp. 2590–2596.Google Scholar
Rubin, R.R., Peyrot, M., Kruger, D.F. and Travis, L.B. (2009), “Barriers to insulin injection therapy”, The Diabetes Educator, Vol. 35 No. 6, pp. 1014–1022.Google Scholar
Shah, R.B., Patel, M., Maahs, D.M. and Shah, V.N. (2016), “Insulin delivery methods: Past, present and future”, International journal of pharmaceutical investigation, Vol. 6 No. 1, p. 1.Google Scholar
Sinha, S.R. and Barry, M. (2011), “Health technologies and innovation in the global health arena”, New England Journal of Medicine, Vol. 365 No. 9, pp. 779–782.Google Scholar
US Food and Drug Administration, (1997), Design control guidance for medical device manufacturers. Center for Devices and Radiological Health.Google Scholar
Veryzer, R.W. and Borja de Mozota, B. (2005), “The impact of user-oriented design on new product development: An examination of fundamental relationships”, Journal of Product Innovation Management, Vol. 22 No. 2, pp. 128–143.Google Scholar
Vredenburg, K., Isensee, S., Righi, C. and University of Texas at Austin/Software Quality Institute, (2002), User-Centered Design: An Integrated Approach. Prentice Hall PTR, Upper Saddle River NJ.Google Scholar
Wijnen, B., Hunt, E.J., Anzalone, G.C. and Pearce, J.M. (2014), “Open-source syringe pump library”, PloS One, Vol. 9 No. 9, p. e107216.Google Scholar
Yock, P.G., Zenios, S., Makower, J., Brinton, T.J., Kumar, U.N., Watkins, F.J., Denend, L., Krummel, T.M. and Kurihara, C.Q. (2015), Biodesign: the process of innovating medical technologies. Cambridge University Press.Google Scholar
Zisser, H.C. (2010), “The OmniPod Insulin Management System: the latest innovation in insulin pump therapy”, Diabetes Therapy, Vol. 1 No. 1, pp. 10–24.Google Scholar