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Design of a Custom-Made Cranial Implant in Patients Suffering from Apert Syndrome

Part of: Design for Additive Manufacturing

Published online by Cambridge University Press:  26 July 2019

Marco Mandolini ,
Agnese Brunzini ,
Eleonora Brandoni Serrani ,
Mario Pagnoni ,
Alida Mazzoli  and
Michele Germani
Marco Mandolini*
Affiliation:
Università Politecnica delle Marche;
Agnese Brunzini
Affiliation:
Università Politecnica delle Marche;
Eleonora Brandoni Serrani
Affiliation:
Università Politecnica delle Marche;
Mario Pagnoni
Affiliation:
Università degli Studi di ROMA La Sapienza
Alida Mazzoli
Affiliation:
Università Politecnica delle Marche;
Michele Germani
Affiliation:
Università Politecnica delle Marche;
*
Contact: Mandolini, Marco, Università Politecnica delle Marche, Department of Industrial Engineering and Mathematical Sciences, Italy, m.mandolini@univpm.it

Abstract

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This study defines a methodological procedure for the design and manufacturing of a prosthetic implant for the reconstruction of a midsagittal bony-deficiency of the skull due to the Apert congenital disorder. Conventional techniques for craniofacial defects reconstruction rely on the mirrored-image technique. When the cranial lesion extends over the midline or in case of bilateral defects, other approaches based on thin plate spline interpolation or constrained anatomical deformation are applied.

The proposed method uses the anthropometric theory of cranial landmarks identification for the retrieval of a template healthy skull, useful as a guide in the successive implant design. Then, anatomical deformation of the region of interest and free-form modelling allow to get the customized shape of the implant. A full bulk and a porous implant have been provided according to the surgeon advises.

The models have been 3D printed for a pre-surgical analysis and further treatment plan. They fulfilled the expectancies of the surgeon thus positive results are predictable.

This methodology results to be reproducible to any other craniofacial defect spanning over the entire skull.

Keywords

Additive ManufacturingBiomedical designDesign processImplant designApert Syndrome
Type
Article
Information
Proceedings of the Design Society: International Conference on Engineering Design , Volume 1 , Issue 1 , July 2019 , pp. 709 - 718
Creative Commons
Creative Common License - CCCreative Common License - BYCreative Common License - NCCreative Common License - ND
This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work.
Copyright
© The Author(s) 2019

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