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Pittsburgh Registry of Infant Multiplets (PRIM): An Update

Published online by Cambridge University Press:  21 February 2012

Elizabeth A. Jenkins ,
Brion S. Maher ,
Mary L. Marazita ,
Ralph E. Tarter ,
Jennifer B. Ganger ,
Margaret Watt-Morse  and
Michael M. Vanyukov
Elizabeth A. Jenkins
Affiliation:
Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Brion S. Maher
Affiliation:
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pennsylvania, United States of America.
Mary L. Marazita
Affiliation:
Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pennsylvania, United States of America.
Ralph E. Tarter
Affiliation:
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Jennifer B. Ganger
Affiliation:
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Margaret Watt-Morse
Affiliation:
Magee-Womens Hospital, Pittsburgh, Pennsylvania, United States of America.
Michael M. Vanyukov*
Affiliation:
Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America. mmv@pitt.edu
*
*Address for correspondence: Michael Vanyukov, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA.

Abstract

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This article is an updated review of the Pittsburgh Registry of Infant Multiplets including recruitment methods, data collection, and results of pilot studies conducted in this registry. The main goal of the registry is to study psychological development. The risk for behavior disorders including substance use disorders, as well as language development and dental health are among research targets. Pilot data on the heritability of minor physical anomalies and neuropsychological characteristics (Continuous Performance Test) are reported.

Type
Articles/United States of America
Information
Twin Research and Human Genetics , Volume 9 , Issue 6 , 01 December 2006 , pp. 1006 - 1008
Copyright
Copyright © Cambridge University Press 2006