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Semen sexing and its impact on fertility and genetic gain in cattle

Published online by Cambridge University Press:  19 March 2024

Sunil Kumar Open the ORCID record for Sunil Kumar [Opens in a new window] ,
Ankit Magotra Open the ORCID record for Ankit Magotra [Opens in a new window] ,
Manoj Kumar Open the ORCID record for Manoj Kumar [Opens in a new window] ,
D.S. Dalal  and
Sonu Kumari
Sunil Kumar*
Affiliation:
Department of Livestock Farm Complex, LUVAS, Hisar 125004, Haryana, India
Ankit Magotra
Affiliation:
Department of Animal Genetics and Breeding, LUVAS, Hisar 125004, Haryana, India
Manoj Kumar
Affiliation:
Department of Livestock Farm Complex, LUVAS, Hisar 125004, Haryana, India
D.S. Dalal
Affiliation:
Department of Animal Genetics and Breeding, LUVAS, Hisar 125004, Haryana, India
Sonu Kumari
Affiliation:
Department of Livestock Farm Complex, LUVAS, Hisar 125004, Haryana, India
*
Corresponding author: Sunil Kumar; Email: drsunil@luvas.edu.in
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Summary

Semen sexing is among one of the most remarkable inventions of the past few decades in the field of reproductive biotechnology. The urge to produce offspring of a desired sex has remained since traditional times. Researchers have tried many methods for accurate semen sexing, but only the flow cytometry method has proved to be effective for commercial utilization. However, there were always concerns about the effects of sexed semen, especially on fertility and the rate of genetic gain. Some concerns were genuine because of factors such as low semen dosage in sexed semen straws and damage to sperm during the sorting process. Various researchers have conducted numerous studies to find out the effect of sexed semen on fertility and, in this article, we reflect on their findings. Initially, there were comparatively much lower conception rates (∼70% of conventional semen) but, with refinement in technology, this gap is bridging and the use of sexed semen will increase over time. Concerning genetic gain with use of sexed semen, a positive effect on rate of genetic progress with the use of sexed semen has been observed based on various simulation studies, although there has been a mild increase in inbreeding.

Keywords

FertilityGenetic progressPregnancy rateSexed semenSperm concentration
Type
Review Article
Information
Zygote , First View , pp. 1 - 10
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© The Author(s), 2024. Published by Cambridge University Press

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