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Biomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: results from the HCHS/SOL SOLNAS study
- JM Beasley, M Jung, N Tasevska, WW Wong, AM Siega-Riz, D Sotres-Alvarez, MD Gellman, JR Kizer, PA Shaw, J Stamler, M Stoutenberg, L Van Horn, AA Franke, J Wylie-Rosett, Y Mossavar-Rahmani
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- Journal:
- Public Health Nutrition / Volume 19 / Issue 18 / December 2016
- Published online by Cambridge University Press:
- 24 June 2016, pp. 3256-3264
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Objective
Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake.
DesignThe Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants’ diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants.
SettingFour centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA.
SubjectsMen and women (n 477) aged 18–74 years.
ResultsThe geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=−0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake.
ConclusionsPossible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.
Responding to health inequities: Indigenous health system innovations
- J. G. Lavoie, D. Kornelsen, L. Wylie, J. Mignone, J. Dwyer, Y. Boyer, A. Boulton, K. O'Donnell
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- Journal:
- Global Health, Epidemiology and Genomics / Volume 1 / 2016
- Published online by Cambridge University Press:
- 22 August 2016, e14
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- 2016
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Over the past decades, Indigenous communities around the world have become more vocal and mobilized to address the health inequities they experience. Many Indigenous communities we work with in Canada, Australia, Latin America, the USA, New Zealand and to a lesser extent Scandinavia have developed their own culturally-informed services, focusing on the needs of their own community members. This paper discusses Indigenous healthcare innovations from an international perspective, and showcases Indigenous health system innovations that emerged in Canada (the First Nation Health Authority) and Colombia (Anas Wayúu). These case studies serve as examples of Indigenous-led innovations that might serve as models to other communities. The analysis we present suggests that when opportunities arise, Indigenous communities can and will mobilize to develop Indigenous-led primary healthcare services that are well managed and effective at addressing health inequities. Sustainable funding and supportive policy frameworks that are harmonized across international, national and local levels are required for these organizations to achieve their full potential. In conclusion, this paper demonstrates the value of supporting Indigenous health system innovations.
Contributors
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- By Mitchell Aboulafia, Frederick Adams, Marilyn McCord Adams, Robert M. Adams, Laird Addis, James W. Allard, David Allison, William P. Alston, Karl Ameriks, C. Anthony Anderson, David Leech Anderson, Lanier Anderson, Roger Ariew, David Armstrong, Denis G. Arnold, E. J. Ashworth, Margaret Atherton, Robin Attfield, Bruce Aune, Edward Wilson Averill, Jody Azzouni, Kent Bach, Andrew Bailey, Lynne Rudder Baker, Thomas R. Baldwin, Jon Barwise, George Bealer, William Bechtel, Lawrence C. Becker, Mark A. Bedau, Ernst Behler, José A. Benardete, Ermanno Bencivenga, Jan Berg, Michael Bergmann, Robert L. Bernasconi, Sven Bernecker, Bernard Berofsky, Rod Bertolet, Charles J. Beyer, Christian Beyer, Joseph Bien, Joseph Bien, Peg Birmingham, Ivan Boh, James Bohman, Daniel Bonevac, Laurence BonJour, William J. Bouwsma, Raymond D. Bradley, Myles Brand, Richard B. Brandt, Michael E. Bratman, Stephen E. Braude, Daniel Breazeale, Angela Breitenbach, Jason Bridges, David O. Brink, Gordon G. Brittan, Justin Broackes, Dan W. Brock, Aaron Bronfman, Jeffrey E. Brower, Bartosz Brozek, Anthony Brueckner, Jeffrey Bub, Lara Buchak, Otavio Bueno, Ann E. Bumpus, Robert W. Burch, John Burgess, Arthur W. Burks, Panayot Butchvarov, Robert E. Butts, Marina Bykova, Patrick Byrne, David Carr, Noël Carroll, Edward S. Casey, Victor Caston, Victor Caston, Albert Casullo, Robert L. Causey, Alan K. L. Chan, Ruth Chang, Deen K. Chatterjee, Andrew Chignell, Roderick M. Chisholm, Kelly J. Clark, E. J. Coffman, Robin Collins, Brian P. Copenhaver, John Corcoran, John Cottingham, Roger Crisp, Frederick J. Crosson, Antonio S. Cua, Phillip D. Cummins, Martin Curd, Adam Cureton, Andrew Cutrofello, Stephen Darwall, Paul Sheldon Davies, Wayne A. Davis, Timothy Joseph Day, Claudio de Almeida, Mario De Caro, Mario De Caro, John Deigh, C. F. Delaney, Daniel C. Dennett, Michael R. DePaul, Michael Detlefsen, Daniel Trent Devereux, Philip E. Devine, John M. Dillon, Martin C. Dillon, Robert DiSalle, Mary Domski, Alan Donagan, Paul Draper, Fred Dretske, Mircea Dumitru, Wilhelm Dupré, Gerald Dworkin, John Earman, Ellery Eells, Catherine Z. Elgin, Berent Enç, Ronald P. Endicott, Edward Erwin, John Etchemendy, C. Stephen Evans, Susan L. Feagin, Solomon Feferman, Richard Feldman, Arthur Fine, Maurice A. Finocchiaro, William FitzPatrick, Richard E. Flathman, Gvozden Flego, Richard Foley, Graeme Forbes, Rainer Forst, Malcolm R. Forster, Daniel Fouke, Patrick Francken, Samuel Freeman, Elizabeth Fricker, Miranda Fricker, Michael Friedman, Michael Fuerstein, Richard A. Fumerton, Alan Gabbey, Pieranna Garavaso, Daniel Garber, Jorge L. A. Garcia, Robert K. Garcia, Don Garrett, Philip Gasper, Gerald Gaus, Berys Gaut, Bernard Gert, Roger F. Gibson, Cody Gilmore, Carl Ginet, Alan H. Goldman, Alvin I. Goldman, Alfonso Gömez-Lobo, Lenn E. Goodman, Robert M. Gordon, Stefan Gosepath, Jorge J. E. Gracia, Daniel W. Graham, George A. Graham, Peter J. Graham, Richard E. Grandy, I. Grattan-Guinness, John Greco, Philip T. Grier, Nicholas Griffin, Nicholas Griffin, David A. Griffiths, Paul J. Griffiths, Stephen R. Grimm, Charles L. Griswold, Charles B. Guignon, Pete A. Y. Gunter, Dimitri Gutas, Gary Gutting, Paul Guyer, Kwame Gyekye, Oscar A. Haac, Raul Hakli, Raul Hakli, Michael Hallett, Edward C. Halper, Jean Hampton, R. James Hankinson, K. R. Hanley, Russell Hardin, Robert M. Harnish, William Harper, David Harrah, Kevin Hart, Ali Hasan, William Hasker, John Haugeland, Roger Hausheer, William Heald, Peter Heath, Richard Heck, John F. Heil, Vincent F. Hendricks, Stephen Hetherington, Francis Heylighen, Kathleen Marie Higgins, Risto Hilpinen, Harold T. Hodes, Joshua Hoffman, Alan Holland, Robert L. Holmes, Richard Holton, Brad W. Hooker, Terence E. Horgan, Tamara Horowitz, Paul Horwich, Vittorio Hösle, Paul Hoβfeld, Daniel Howard-Snyder, Frances Howard-Snyder, Anne Hudson, Deal W. Hudson, Carl A. Huffman, David L. Hull, Patricia Huntington, Thomas Hurka, Paul Hurley, Rosalind Hursthouse, Guillermo Hurtado, Ronald E. Hustwit, Sarah Hutton, Jonathan Jenkins Ichikawa, Harry A. Ide, David Ingram, Philip J. Ivanhoe, Alfred L. Ivry, Frank Jackson, Dale Jacquette, Joseph Jedwab, Richard Jeffrey, David Alan Johnson, Edward Johnson, Mark D. Jordan, Richard Joyce, Hwa Yol Jung, Robert Hillary Kane, Tomis Kapitan, Jacquelyn Ann K. Kegley, James A. Keller, Ralph Kennedy, Sergei Khoruzhii, Jaegwon Kim, Yersu Kim, Nathan L. King, Patricia Kitcher, Peter D. Klein, E. D. Klemke, Virginia Klenk, George L. Kline, Christian Klotz, Simo Knuuttila, Joseph J. Kockelmans, Konstantin Kolenda, Sebastian Tomasz Kołodziejczyk, Isaac Kramnick, Richard Kraut, Fred Kroon, Manfred Kuehn, Steven T. Kuhn, Henry E. Kyburg, John Lachs, Jennifer Lackey, Stephen E. Lahey, Andrea Lavazza, Thomas H. Leahey, Joo Heung Lee, Keith Lehrer, Dorothy Leland, Noah M. Lemos, Ernest LePore, Sarah-Jane Leslie, Isaac Levi, Andrew Levine, Alan E. Lewis, Daniel E. Little, Shu-hsien Liu, Shu-hsien Liu, Alan K. L. Chan, Brian Loar, Lawrence B. Lombard, John Longeway, Dominic McIver Lopes, Michael J. Loux, E. J. Lowe, Steven Luper, Eugene C. Luschei, William G. Lycan, David Lyons, David Macarthur, Danielle Macbeth, Scott MacDonald, Jacob L. Mackey, Louis H. Mackey, Penelope Mackie, Edward H. Madden, Penelope Maddy, G. B. Madison, Bernd Magnus, Pekka Mäkelä, Rudolf A. Makkreel, David Manley, William E. Mann (W.E.M.), Vladimir Marchenkov, Peter Markie, Jean-Pierre Marquis, Ausonio Marras, Mike W. Martin, A. P. Martinich, William L. McBride, David McCabe, Storrs McCall, Hugh J. McCann, Robert N. McCauley, John J. McDermott, Sarah McGrath, Ralph McInerny, Daniel J. McKaughan, Thomas McKay, Michael McKinsey, Brian P. McLaughlin, Ernan McMullin, Anthonie Meijers, Jack W. Meiland, William Jason Melanson, Alfred R. Mele, Joseph R. Mendola, Christopher Menzel, Michael J. Meyer, Christian B. Miller, David W. Miller, Peter Millican, Robert N. Minor, Phillip Mitsis, James A. Montmarquet, Michael S. Moore, Tim Moore, Benjamin Morison, Donald R. Morrison, Stephen J. Morse, Paul K. Moser, Alexander P. D. Mourelatos, Ian Mueller, James Bernard Murphy, Mark C. Murphy, Steven Nadler, Jan Narveson, Alan Nelson, Jerome Neu, Samuel Newlands, Kai Nielsen, Ilkka Niiniluoto, Carlos G. Noreña, Calvin G. Normore, David Fate Norton, Nikolaj Nottelmann, Donald Nute, David S. Oderberg, Steve Odin, Michael O’Rourke, Willard G. Oxtoby, Heinz Paetzold, George S. Pappas, Anthony J. Parel, Lydia Patton, R. P. Peerenboom, Francis Jeffry Pelletier, Adriaan T. Peperzak, Derk Pereboom, Jaroslav Peregrin, Glen Pettigrove, Philip Pettit, Edmund L. Pincoffs, Andrew Pinsent, Robert B. Pippin, Alvin Plantinga, Louis P. Pojman, Richard H. Popkin, John F. Post, Carl J. Posy, William J. Prior, Richard Purtill, Michael Quante, Philip L. Quinn, Philip L. Quinn, Elizabeth S. Radcliffe, Diana Raffman, Gerard Raulet, Stephen L. Read, Andrews Reath, Andrew Reisner, Nicholas Rescher, Henry S. Richardson, Robert C. Richardson, Thomas Ricketts, Wayne D. Riggs, Mark Roberts, Robert C. Roberts, Luke Robinson, Alexander Rosenberg, Gary Rosenkranz, Bernice Glatzer Rosenthal, Adina L. Roskies, William L. Rowe, T. M. Rudavsky, Michael Ruse, Bruce Russell, Lilly-Marlene Russow, Dan Ryder, R. M. Sainsbury, Joseph Salerno, Nathan Salmon, Wesley C. Salmon, Constantine Sandis, David H. Sanford, Marco Santambrogio, David Sapire, Ruth A. Saunders, Geoffrey Sayre-McCord, Charles Sayward, James P. Scanlan, Richard Schacht, Tamar Schapiro, Frederick F. Schmitt, Jerome B. Schneewind, Calvin O. Schrag, Alan D. Schrift, George F. Schumm, Jean-Loup Seban, David N. Sedley, Kenneth Seeskin, Krister Segerberg, Charlene Haddock Seigfried, Dennis M. Senchuk, James F. Sennett, William Lad Sessions, Stewart Shapiro, Tommie Shelby, Donald W. Sherburne, Christopher Shields, Roger A. Shiner, Sydney Shoemaker, Robert K. Shope, Kwong-loi Shun, Wilfried Sieg, A. John Simmons, Robert L. Simon, Marcus G. Singer, Georgette Sinkler, Walter Sinnott-Armstrong, Matti T. Sintonen, Lawrence Sklar, Brian Skyrms, Robert C. Sleigh, Michael Anthony Slote, Hans Sluga, Barry Smith, Michael Smith, Robin Smith, Robert Sokolowski, Robert C. Solomon, Marta Soniewicka, Philip Soper, Ernest Sosa, Nicholas Southwood, Paul Vincent Spade, T. L. S. Sprigge, Eric O. Springsted, George J. Stack, Rebecca Stangl, Jason Stanley, Florian Steinberger, Sören Stenlund, Christopher Stephens, James P. Sterba, Josef Stern, Matthias Steup, M. A. Stewart, Leopold Stubenberg, Edith Dudley Sulla, Frederick Suppe, Jere Paul Surber, David George Sussman, Sigrún Svavarsdóttir, Zeno G. Swijtink, Richard Swinburne, Charles C. Taliaferro, Robert B. Talisse, John Tasioulas, Paul Teller, Larry S. Temkin, Mark Textor, H. S. Thayer, Peter Thielke, Alan Thomas, Amie L. Thomasson, Katherine Thomson-Jones, Joshua C. Thurow, Vzalerie Tiberius, Terrence N. Tice, Paul Tidman, Mark C. Timmons, William Tolhurst, James E. Tomberlin, Rosemarie Tong, Lawrence Torcello, Kelly Trogdon, J. D. Trout, Robert E. Tully, Raimo Tuomela, John Turri, Martin M. Tweedale, Thomas Uebel, Jennifer Uleman, James Van Cleve, Harry van der Linden, Peter van Inwagen, Bryan W. Van Norden, René van Woudenberg, Donald Phillip Verene, Samantha Vice, Thomas Vinci, Donald Wayne Viney, Barbara Von Eckardt, Peter B. M. Vranas, Steven J. Wagner, William J. Wainwright, Paul E. Walker, Robert E. Wall, Craig Walton, Douglas Walton, Eric Watkins, Richard A. Watson, Michael V. Wedin, Rudolph H. Weingartner, Paul Weirich, Paul J. Weithman, Carl Wellman, Howard Wettstein, Samuel C. Wheeler, Stephen A. White, Jennifer Whiting, Edward R. Wierenga, Michael Williams, Fred Wilson, W. Kent Wilson, Kenneth P. Winkler, John F. Wippel, Jan Woleński, Allan B. Wolter, Nicholas P. Wolterstorff, Rega Wood, W. Jay Wood, Paul Woodruff, Alison Wylie, Gideon Yaffe, Takashi Yagisawa, Yutaka Yamamoto, Keith E. Yandell, Xiaomei Yang, Dean Zimmerman, Günter Zoller, Catherine Zuckert, Michael Zuckert, Jack A. Zupko (J.A.Z.)
- Edited by Robert Audi, University of Notre Dame, Indiana
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- The Cambridge Dictionary of Philosophy
- Published online:
- 05 August 2015
- Print publication:
- 27 April 2015, pp ix-xxx
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Contributors
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- By Ainsworth Shaaron, Ayres Paul, Azevedo Roger, Bediou Benoit, Britt Anne, Kirsten R. Butcher, Chen Fei, Michelene T. H. Chi, Richard E. Clark, Ruth Colvin Clark, Sharon J. Derry, David F. Feldon, Fiorella Logan, J. D. Fletcher, Arthur C. Graesser, Hegarty Mary, HU Xiangen, Allison J. Jaeger, Janssen Jeroen, Cheryl I. Johnson, Ton De Jong, Kalyuga Slava, Kester Liesbeth, Kirschner Femke, Paul A. Kirschner, Susanne P. Lajoie, Ard W. Lazonder, Leutner Detlev, Low Renae, Richard K. Lowe, Richard E. Mayer, Benjamin D. Nye, Paas Fred, Pilegard Celeste, Jan L. Plass, Heather A. Priest, Renkl Alexander, Rouet Jean-FranÇois, Christopher A. Sanchez, Scheiter Katharina, Schmeck Annett, Schnotz Wolfgang, Ruth N. Schwartz, Bruce L. Sherin, Miriam Gamoran Sherin, Sweller John, Tobias Sigmund, Tamara Van Gog, Jeroen J. G. Van MerriËNboer, Jennifer Wiley, Alexander P. Wind, Ruth Wylie
- Edited by Richard E. Mayer, University of California, Santa Barbara
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- The Cambridge Handbook of Multimedia Learning
- Published online:
- 05 August 2014
- Print publication:
- 28 July 2014, pp ix-x
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The GALAH survey
- B. Anguiano, K. Freeman, J. Bland-Hawthorn, G. De Silva, M. Asplund, D. Carollo, V. D'Orazi, S. Keller, S. Martell, S. Sharma, C. Sneden, L. Wylie de Boer, D. Zucker, T. Zwitter, the GALAH survey team
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- Journal:
- Proceedings of the International Astronomical Union / Volume 9 / Issue S298 / May 2013
- Published online by Cambridge University Press:
- 06 January 2014, pp. 322-325
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- May 2013
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HERMES is a new high-resolution multi-object spectrograph on the Anglo Australian Telescope. The primary science driver for HERMES is the GALAH survey, GALactic Archaeology with HERMES. We are planning a spectroscopic survey of about a million stars, aimed at using chemical tagging techniques to reconstruct the star-forming aggregates that built up the disk, the bulge and halo of the Galaxy. This project will benefit greatly from the stellar distances and transverse motions from the Gaia mission.
s- and r-Process Element Abundances in the CMD of 47 Tucanæ Using the Robert Stobie Spectrograph on SALT*
- C. C. Worley, P. L. Cottrell, E. C. Wylie de Boer
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- Journal:
- Publications of the Astronomical Society of Australia / Volume 25 / Issue 2 / 2008
- Published online by Cambridge University Press:
- 05 March 2013, pp. 53-62
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A recent study by Wylie et al. (2006) has revealed that s-process element abundances are enhanced relative to iron in both red giant branch and asymptotic giant branch stars of 47 Tuc. A more detailed investigation into s-process element abundances throughout the colour-magnitude diagram of 47 Tuc is vital in order to determine whether the observed enhancements are intrinsic to the cluster. This paper explores this possibility through observational and theoretical means. The visibility of s- and r-process element lines in synthetic spectra of giant and dwarf stars throughout the colour magnitude diagram of 47 Tuc has been explored. It was determined that a resolving power of 10 000 was sufficient to observe s-process element abundance variations in globular cluster giant-branch stars. These synthetic results were compared with the spectra of eleven 47 Tuc giant branch stars observed during the performance verification of the Robert Stobie Spectrograph on the Southern African Large Telescope. Three s-process elements (Zr, Ba and Nd) and one r-process element (Eu) were investigated. No abundance variations were found such that [X/Fe] = 0.0 ± 0.5 dex. It was concluded that this resolving power, R ∼ 5000, was not sufficient to obtain exact abundances but upper limits on the s-process element abundances could be determined.
Grassland systems of red meat production: integration between biodiversity, plant nutrient utilisation, greenhouse gas emissions and meat nutritional quality
- L. E. R. Dawson, P. O'Kiely, A. P. Moloney, J. E. Vipond, A. R. G. Wylie, A. F. Carson, J. Hyslop
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Government policies relating to red meat production take account of the carbon footprint, environmental impact, and contributions to human health and nutrition, biodiversity and food security. This paper reviews the impact of grazing on these parameters and their interactions, identifying those practices that best meet governments’ strategic goals. The recent focus of research on livestock grazing and biodiversity has been on reducing grazing intensity on hill and upland areas. Although this produces rapid increases in sward height and herbage mass, changes in structural diversity and plant species are slower, with no appreciable short-term increases in biodiversity so that environmental policies that simply involve reductions in numbers of livestock may not result in increased biodiversity. Furthermore, upland areas rely heavily on nutrient inputs to pastures so that withdrawal of these inputs can threaten food security. Differences in grazing patterns among breeds increase our ability to manage biodiversity if they are matched appropriately to different conservation grazing goals. Lowland grassland systems differ from upland pastures in that additional nutrients in the form of organic and inorganic fertilisers are more frequently applied to lowland pastures. Appropriate management of these nutrient applications is required, to reduce the associated environmental impact. New slurry-spreading techniques and technologies (e.g. the trailing shoe) help reduce nutrient losses but high nitrogen losses from urine deposition remain a key issue for lowland grassland systems. Nitrification inhibitors have the greatest potential to successfully tackle this problem. Greenhouse gas (GHG) emissions are lower from indoor-based systems that use concentrates to shorten finishing periods. The challenge is to achieve the same level of performance from grass-based systems. Research has shown potential solutions through the use of forages containing condensed tannins or establishing swards with a high proportion of clover and high-sugar grasses. Relative to feeding conserved forage or concentrates, grazing fresh grass not only reduces GHG emissions but also enhances the fatty acid composition of meat in terms of consumer health. It is possible to influence biodiversity, nutrient utilisation, GHG emissions and the nutritional quality of meat in grass-based systems, but each of these parameters is intrinsically linked and should not be considered in isolation. Interactions between these parameters must be considered carefully when policies are being developed, in order to ensure that strategies designed to achieve positive gains in one category do not lead to a negative impact in another. Some win–win outcomes are identified.
The effect of a novel complementary feedstuff on canine faecal consistency and odour
- C L Carmichael, M Scott, A Wylie, D Wells, V E Beattie
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- Journal:
- Advances in Animal Biosciences / Volume 1 / Issue 1 / April 2010
- Published online by Cambridge University Press:
- 29 November 2010, p. 108
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- April 2010
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Effects of feeding level and protein content of milk replacer on the performance of dairy herd replacements
- S. J. Morrison, H. C. F. Wicks, R. J. Fallon, J. Twigge, L. E. R. Dawson, A. R. G. Wylie, A. F. Carson
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It has been suggested that United Kingdom recommendations for feeding the neonatal calf (∼500 g milk replacer (MR)/day; ∼200–230 g CP/kg milk powder) are inadequate to sustain optimal growth rates in early life. The current study was undertaken with 153 high genetic merit, male and female Holstein-Friesian calves (PIN2000 = £48) born between September and March, with heifers reared and bred to calve at 24 months of age. Calves were allocated to one of four pre-weaning dietary treatments arranged in a 2 MR feeding level (5 v. 10 l/day) × 2 MR protein content (210 v. 270 g CP/kg dry matter (DM)) factorial design. MR was reconstituted at a rate of 120 g/l of water, throughout, and was offered via computerised automated milk feeders. Calves were introduced to pre-weaning diets at 5 days of age and weaned at day 56. During the first 56 days of life, calves offered 10 l MR/day had significantly higher liveweight gains (P < 0.001) than calves fed 5 l MR/day. No significant differences in liveweight gain were found between calves fed 210 g CP/kg DM MR and those fed 270 g CP/kg DM MR from birth to day 56. Differences in live weight and body size due to feeding level disappeared by day 90. Neither MR feeding level nor MR CP content affected age at first service or age at successful service, and with no milk production effects, the results indicate no post-weaning benefits of increased nutrition during the milk-feeding period in dairy heifers.
The effect of rearing regime on the development of the mammary gland and claw abnormalities in high genetic merit Holstein-Friesian dairy herd replacements
- A. F. Carson, L. E. R. Dawson, A. R. G. Wylie, F. J. Gordon
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- Journal:
- Animal Science / Volume 78 / Issue 3 / June 2004
- Published online by Cambridge University Press:
- 18 August 2016, pp. 497-509
- Print publication:
- June 2004
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One hundred and eight high genetic merit Holstein-Friesian heifers were used to determine the effects of rearing regime on the development of the mammary gland and claw abnormalities. Heifers were allocated to one of four rearing regimes at 7 weeks of age and slaughtered at 18 (s.d.0.7) months of age; mating commenced at 14 months of age. Treatment 1 heifers were reared to calve at 540 kg and treatments 2, 3 and 4 heifers reared to calve at 620 kg. Treatment 1 and 2 heifers were offered grass silage-based diets during the winter and grass-based diets during the summer; treatment 2 heifers received additional concentrates. Treatment 3 heifers were offered a straw/concentrate diet during the winter and a grass-based diet during the summer. Treatment 4 heifers received the same winter diets as treatment 3 but were housed and offered a straw/concentrate diet in summer. Increasing plane of nutrition increased the weight of dissected udder fat (P < 0.01), but had no effect on the weight or chemical composition of dissected udder parenchyma. Offering straw- compared with silage-based diets reduced fat deposition in the udder (P < 0.01) and increased the proportion of parenchyma in the udder (P < 0.01). Keeping heifers housed during the first summer and offering straw-based diets relative to those turned out to grass had no effect on weight of fat although there was a tendency towards a reduction in the proportion of parenchyma in the udder (P < 0.06). Heifers reared on a low plane of nutrition had lower values for heel height (P < 0.001), lateral claw length (P < 0.001) and heel erosion scores (P < 0.01). A higher plane of nutrition also increased live weight/sole area although this was only significantly higher for treatment 3 (P < 0.05) compared with treatment 1 heifers. Housing heifers in the first summer increased the incidence of feet lesions in the white line area and solear area relative to turning heifers out to grass in the first summer (P < 0.05).
Rheology of suspensions with high particle inertia and moderate fluid inertia
- JONATHAN J. WYLIE, DONALD L. KOCH, ANTHONY J. C. LADD
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- Journal:
- Journal of Fluid Mechanics / Volume 480 / 10 April 2003
- Published online by Cambridge University Press:
- 30 April 2003, pp. 95-118
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We consider the averaged flow properties of a suspension in which the Reynolds number based on the particle diameter is finite so that the inertia of the fluid phase is important. When the inertia of the particles is sufficiently large, their trajectories, between successive particle collisions, are only weakly affected by the interstitial fluid. If the particle collisions are nearly elastic the particle velocity distribution is close to an isotropic Maxwellian. The rheological properties of the suspension can then be determined using kinetic theory, provided that one knows the granular temperature (energy contained in the particle velocity fluctuations). This energy results from a balance of the shear work with the loss due to the viscous dissipation in the interstitial fluid and the dissipation due to inelastic collisions. We use lattice-Boltzmann simulations to calculate the viscous dissipation as a function of particle volume fraction and Reynolds number (based on the particle diameter and granular temperature). The Reynolds stress induced in the interstitial fluid by the random motion of the particles is also determined. We also consider the case where the interstitial fluid is moving relative to the particles, as would occur if the particles experienced an external body force. Owing to the nonlinearity of the equations of motion for the interstitial fluid, there is a coupling between the viscous dissipation caused by the fluctuating motion of the particles and the drag associated with a mean relative motion of the two phases, and this coupling is explored by computing the dissipation and mean drag for a range of values of the Reynolds numbers based on the mean relative velocity and the granular temperature.
Effects of incremental changes in forage: concentrate ratio on plasma hormone and metabolite concentrations and products of rumen fermentation in fattening beef steers
- C. L. Thorp, A.R.G. Wylie, R.W. J. Steen, C. Shaw, J. D. McEvoy
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- Journal:
- Animal Science / Volume 71 / Issue 1 / August 2000
- Published online by Cambridge University Press:
- 18 August 2016, pp. 93-109
- Print publication:
- August 2000
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As part of an investigation of factors responsible for a previously reported lower efficiency of carcass lean gain in steers offered grass silage diets, 16 Simmental × Friesian steers (515 (s.e. 6·4) kg) were offered perennial ryegrass silage ad libitum (C0) or silage plus rolled barley at 200 (C20), 400 (C40) or 600 (C60) g/kg total diet dry matter (DM). Barley-supplemented diets were intake-restricted to provide equal DM and metabolizable energy (ME) intakes to those offered C0. Eight steers were selected at random to determine the ME contents of the diets by open-circuit respiration calorimetry. The other eight steers were offered the same diets and were blood-sampled at 20- to 60-min intervals, for 10 h, to monitor changes in the concentrations of a number of nutritionally related plasma metabolites and hormones. Estimated ME intakes in these steers were 85·7, 83·1, 84·4 and 86·2 (s.e. 0·91) MJ/day from diets C0, C20, C40 and C60 respectively. Rumen-fistulated Hereford × Friesian steers provided 24-h rumen data for the same diets offered at equal amounts of ME per kg metabolic live weight.
Mean 24-h plasma concentrations of insulin and insulin-like growth factor 1 (IGF-1) were linearly and positively related (P < 0·01 and P < 0·001 respectively) and glucagon quadratically related (P < 0·05) to the proportion of barley in the diet. Plasma insulin increased after feeding on all diets but concentrations on diets C40 and C60 were significantly higher than those on C0 and C20 at all post-feeding sampling times up to 9 h after feeding. Plasma IGF-1 concentrations increased above pre-feeding levels following feeding of the higher barley diets (C40 and C60; P = 0·053) but remained unchanged in steers offered C0 and C20. Mean plasma concentrations of glucose were unaffected by diet but those of β-hydroxybutyrate (BOHB) and urea were positively and negatively related respectively (both P < 0·001) to the proportion of barley in the diet. Plasma BOHB and urea concentrations also changed with time after feeding (P < 0·001). Amongst the rumen parameters measured (pH; ammonia and volatile fatty acid concentrations and proportions) only the mean 24-h concentrations and proportions of butyrate were positively related to the proportion of barley in the diet (P = 0·051 and P < 0·05 respectively). All rumen parameters were affected by time after feeding (acetate, P < 0·01; others, P < 0·001) but there was no interaction between treatment and time for any parameter.
53 - Evidence for population-based testing for hemochromatosis
- from Part XII - Hemochromatosis: societal and ethical issues
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- By Mary E. Cogswell, Centers for Disease Control and Prevention, Atlanta, Georgia, Sharon M. McDonnell, Centers for Disease Control and Prevention, Atlanta, Georgia, Muin J. Khoury, Centers for Disease Control and Prevention, Atlanta, Georgia, Adele L. Franks, Centers for Disease Control and Prevention, Atlanta, Georgia, Wylie Burke, University of Washington, Seattle, Gary Brittenham, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
- Edited by James C. Barton, Southern Iron Disorders Center, Alabama, Corwin Q. Edwards, University of Utah
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- Book:
- Hemochromatosis
- Published online:
- 05 August 2011
- Print publication:
- 13 January 2000, pp 544-554
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- Chapter
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Summary
Introduction
As many as 1 million persons in the United States are affected by hemochromatosis, a genetic condition characterized by excess iron absorption and pathologic iron deposition in tissue. If undetected and untreated, hemochromatosis can result in illness (such as cirrhosis, hepatoma, diabetes, cardiomyopathy, arthritis, arthropathy, and hypopituitarism with hypogonadism) and death. The identification and treatment of asymptomatic persons in whom iron measures are elevated but hemochromatosis is not clinically apparent have been recommended as a potentially cost-effective strategy for preventing hemochromatosis-associated illness and death. Nonetheless, some experts argue that before universal screening can be recommended, the clinical expression and natural history of hemochromatosis must be clarified and the infrastructure necessary to support a universal screening program (including laboratory standardization and physician education) must be established. The recent discovery of a gene associated with hemochromatosis has made it possible to use DNA testing along with, or instead of, iron measures in screening. Although this discovery has increased interest in hemochromatosis, it has also raised new questions about screening for and diagnosis of the disease. One objective of the meeting on Iron Overload, Public Health, and Genetics, sponsored by the Centers for Disease Control and Prevention and the National Institutes of Health in March 1997, was to review the scientific information available on population screening for hemochromatosis. Our assessment of the evidence and recommendations for action are presented here.
Methods for evaluating the evidence for population screening for hemochromatosis
US Preventive Services Task Force criteria were used15 to evaluate evidence related to population screening for hemochromatosis that was presented at the meeting on Iron Overload, Public Health and Genetics or was published before August 1997.
Non-Linear Optical Characteristics of Novel Porphyrin Dye Media
- K. J. McEwan, J. M. Robertson, A. P. Wylie, H. L. Anderson
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- Journal:
- MRS Online Proceedings Library Archive / Volume 479 / 1997
- Published online by Cambridge University Press:
- 03 September 2012, 29
- Print publication:
- 1997
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- Article
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Measurements of sensitive RSA phenonema in new porphyrin dyes are presented. Both the linear and non-linear optical properties are shown to depend strongly on the molecular structure. A detailed analysis of two of the porphyrins reveals that inter-systems crossing rate and the excited state absorption profile are strongly influenced by substitution of a heavy atom into the central atom position. It is shown that by appropriate choice of wavelength values in excess of 30 can be achieved for the material parameter σex / σgr. This value compares well with previously reported results and is achieved in conjunction with excited state lifetimes on the order of 300 ns.