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Bound Carbohydrates in Nature

£72.00

Part of Lezioni Lincee

  • Author: Leonard Warren, The Wistar Institute of Anatomy and Biology, Philadelphia
  • Date Published: February 1994
  • availability: Available
  • format: Hardback
  • isbn: 9780521442312

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About the Authors
  • This 1994 book is based on a series of six lectures delivered at the University of Sienna under the auspices of the Lezioni Lincee. The content of the book reflects and delineates the author's career in biochemical research. The lectures revolve around the special role which bound carbohydrates play in nature. Also discussed are the properties of membrane glycoproteins, involved in the resistance of cells to drugs. The metabolism of sugars and sialic acids, which form a pivotal role in the author's research, are covered in detail. The book chronicles just some of the huge advances which have been made in biochemistry over the past few decades and will prove an invaluable and entertaining first hand account for researchers and graduate students.

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    Product details

    • Date Published: February 1994
    • format: Hardback
    • isbn: 9780521442312
    • length: 126 pages
    • dimensions: 216 x 140 x 11 mm
    • weight: 0.31kg
    • contains: 30 b/w illus. 7 tables
    • availability: Available
  • Table of Contents

    1. Introduction, history, microheterogeneity of bound carbohydrates
    function of bound carbohydrates
    inducible changes in bound carbohydrates
    programmed changes in bound carbohydrates
    a possible role for bound carbohydrates
    2. Sialic acids
    distribution of sialic acids in nature
    the metabolism of hexamines and sialic acids
    metabolic control of hexosamines and sialic acids
    asparagine N-glycosylation
    processing of lysomal enzymes
    biosynthesis of O-linked oligosaccarides
    modification of sialic acids
    sialidases
    genetic metabolic disorders involving sialic acids, glycosidases, bound carbohydrates in malignancy
    3. Multidrug resistance, properties of P-glycoprotein
    lysomes and multidrug resistance
    kinetics of influx and efflux of drugs, modulation of multidrug resistance
    the role of lipids in the accumulation of drugs by MDR cells
    P-170 and membrane lipids
    Overview.

  • Author

    Leonard Warren, The Wistar Institute of Anatomy and Biology, Philadelphia

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