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Look Inside Dynamics of Proteins and Nucleic Acids

Dynamics of Proteins and Nucleic Acids

£64.99

textbook
  • Date Published: May 1988
  • availability: Available
  • format: Paperback
  • isbn: 9780521356527

£ 64.99
Paperback

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About the Authors
  • This book is a self-contained introduction to the theory of atomic motion in proteins and nucleic acids. An understanding of such motion is essential because it plays a crucially important role in biological activity. The authors, both of whom are well known for their work in this field, describe in detail the major theoretical methods that are likely to be useful in the computer-aided design of drugs, enzymes and other molecules. A variety of theoretical and experimental studies is described and these are critically analyzed to provide a comprehensive picture of dynamic aspects of biomolecular structure and function. The book will be of interest to graduate students and research workers in structural biochemistry (X-ray diffraction and NMR), theoretical chemistry (liquids and polymers), biophysics, enzymology, molecular biology, pharmaceutical chemistry, genetic engineering and biotechnology.

    Reviews & endorsements

    'McCammon and Harvey's account is easily read and at the same time rewarding to those seeking deeper insight. With its comprehensive and well-balanced list of references, and its review of all the main developments, it will be an invaluable companion to those interested in the dynamics of biological macromolecules.' Nature

    'This book will undoubtedly serve as a generally good introductory text for expert and non-expert alike.' The Times Higher Education Supplement

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    Product details

    • Date Published: May 1988
    • format: Paperback
    • isbn: 9780521356527
    • length: 248 pages
    • dimensions: 229 x 152 x 14 mm
    • weight: 0.37kg
    • availability: Available
  • Table of Contents

    Preface
    1. Introduction
    2. Structure of proteins, nucleic acids, and their solvent surroundings
    3. Dynamics of proteins, nucleic acids, and their solvent surroundings
    4. Theoretical methods
    5. Short time dynamics
    6. Local structural transitions
    7. Global structural changes
    8. Dynamics of molecular associations
    9. Recent developments and future directions
    Appendices
    References
    Index.

  • Authors

    J. Andrew McCammon

    Stephen C. Harvey, Georgia Institute of Technology

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