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Behavioral Genetics of the Mouse

Volume 1. Genetics of Behavioral Phenotypes

$155.00

Part of Cambridge Handbooks in Behavioral Genetics

W. E. Crusio, R. T. Gerlai, H. P. Lipp, D. P. Wolfer, D. Wahlsten, J. C. Crabbe, J. F. Willott, G. T. Prusky, N. M. Alam, S. B. Smith, J. S. Mogil, H. Schellinck, B. Slotnick, J. Boughter, R. Lalonde, C. Strazielle, F. Cirulli, E. Alleva, R. J. Bodnar, S. R. Lewis, B. Kest, F. G. Biddle, B. A. Eales, B. Possidente, A. Holmes, R. Benno, M. E. Hahn, C. F. Plappert, P. K. D. Pilz, H. Gershenfeld, P. R. Canavello, J. M. Cachat, P. C. Hart, D. L. Murphy, A. V. Kalueff, C. Blanchard, J. Crawley, H. Arakawa, R. Blanchard, L. Niel, D. A. Monks, Abel Bult-Ito, F. Sluyter, S. de Boer, S. C. Maxson, T. J. Gould, S. F. Logue, G. Colacicco, H. Welzl, I. Branchi, L. Ricceri, Herbert Schwegler, T. P. O'Leary, R. E. Brown, E. Dere, A. Zlomuzica, M. A. De Souza Silva, J. P. Huston
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  • Date Published: June 2013
  • availability: In stock
  • format: Hardback
  • isbn: 9781107034815

$155.00
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About the Authors
  • The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

    • Provides essential background knowledge for designing and interpreting studies with genetically modified mice
    • Includes many examples of experimental problems, providing help with experimental design and troubleshooting
    • Each chapter reviews current knowledge about one specific type of behaviour, pointing the reader towards the most important studies in the extensive literature
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    Reviews & endorsements

    "This first volume is a much-needed reference text on the behavioral genetics of the mouse. I am looking forward to the subsequent volumes and expect that together they will provide a panoramic view of the field. Such a series of manuals will be invaluable to students, scientists, and scholars aiming to master the ‘beauties’ of mouse behavior."
    Silvia Mandillo, Genes, Brain and Behavior

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    Product details

    • Date Published: June 2013
    • format: Hardback
    • isbn: 9781107034815
    • length: 357 pages
    • dimensions: 280 x 222 x 23 mm
    • weight: 1.31kg
    • contains: 85 b/w illus.
    • availability: In stock
  • Table of Contents

    Contributor list
    Part I. General:
    1. Current status of the field W. E. Crusio and R. T. Gerlai
    2. Natural neurobiology and behavior of the mouse: relevance for behavioral studies in the laboratory H. P. Lipp and D. P. Wolfer
    3. Ethogram R. T. Gerlai and W. E. Crusio
    4. Replicability and reliability of behavioral tests D. Wahlsten and J. C. Crabbe
    Part II. Perception:
    5. Audition J. F. Willott
    6. Behavioral measurement of mouse visual function G. T. Prusky and N. M. Alam
    7. Tactile system and nociception S. B. Smith and J. S. Mogil
    8. Olfactory acuity in Mus musculus H. Schellinck and B. Slotnick
    9. Taste genetics J. Boughter
    Part III. Autonomous and Motor Behaviors:
    10. Motor coordination in inbred mouse strains and the crucial role of the cerebellum R. Lalonde and C. Strazielle
    11. Reflex development F. Cirulli and E. Alleva
    12. Feeding and drinking R. J. Bodnar, S. R. Lewis and B. Kest
    13. Lateralization F. G. Biddle and B. A. Eales
    14. Rhythms and sleep: circadian and seasonal activity patterns B. Possidente
    15. Exploratory behavior W. E. Crusio
    16. Strains, SNPs and selected lines: genetic factors influencing variation in murine anxiety-like behavior A. Holmes
    17. Genetic influences on infant mouse ultrasonic vocalizations R. Benno and M. E. Hahn
    18. Startle behavior and prepulse inhibition C. F. Plappert and P. K. D. Pilz
    19. Mouse models of stress-induced depression-like behavior: stress vulnerability and antidepressant response as traits H. Gershenfeld
    20. Behavioral phenotyping of mouse grooming and barbering P. R. Canavello, J. M. Cachat, P. C. Hart, D. L. Murphy and A. V. Kalueff
    Part IV. Social Behavior:
    21. Social interaction C. Blanchard, J. Crawley, H. Arakawa and R. Blanchard
    22. Mouse sex: sexual differentiation and sexual behavior in Mus musculus L. Niel and D. A. Monks
    23. Nest-building behavior and the genetic correlation structure of adaptive phenotypes in house mice Abel Bult-Ito
    24. Aggression F. Sluyter, S. de Boer and S. C. Maxson
    Part V. Learning and Memory:
    25. Latent inhibition T. J. Gould and S. F. Logue
    26. Executive function: response inhibition, attention, and cognitive flexibility S. F. Logue and T. J. Gould
    27. Water navigation tasks D. P. Wolfer, G. Colacicco and H. Welzl
    28. Active and passive avoidance I. Branchi and L. Ricceri
    29. Radial maze W. E. Crusio and Herbert Schwegler
    30. Other mazes T. P. O'Leary and R. E. Brown
    31. Cued and contextual fear conditioning R. M. Gerlai
    32. Taste and odor H. Welzl and D. P. Wolfer
    33. Object recognition in the mouse E. Dere, A. Zlomuzica, M. A. De Souza Silva and J. P. Huston
    Index.

  • Editors

    Wim E. Crusio, Université de Bordeaux
    Wim E. Crusio is a Research Director at the French National Research Council (CNRS). With over 35 years experience in mouse behavioral neurogenetics and the phenotyping of mouse behavior, his recent interests cover mouse models of depression, autism and Fragile X Syndrome.

    Frans Sluyter, BioScience Project, Wakefield, Massachusetts
    Frans Sluyter is an expert in (wild) house mouse behavior and neurogenetics. His interests range from aggression, addiction, depression and (stress) coping strategies to gene expression profiles and consciousness.

    Robert T. Gerlai, University of Toronto
    Robert Gerlai has held numerous positions in academia, biotechnology and the pharmaceutical research industry and is currently a professor in the Department of Psychology at the University of Toronto. He studies biological and genetic mechanisms of behavior using reverse and forward genetic and psychopharmacological methods in mice and zebrafish.

    Susanna Pietropaolo, Université de Bordeaux
    Susanna Pietropaolo is currently a researcher at the French National Research Council (CNRS). She is an expert in the behavioral analysis of the laboratory mouse, with a special interest in inter-specific social behaviors. Her recent research focuses on mouse models of social dysfunction, including autism and Fragile X Syndrome.

    Contributors

    W. E. Crusio, R. T. Gerlai, H. P. Lipp, D. P. Wolfer, D. Wahlsten, J. C. Crabbe, J. F. Willott, G. T. Prusky, N. M. Alam, S. B. Smith, J. S. Mogil, H. Schellinck, B. Slotnick, J. Boughter, R. Lalonde, C. Strazielle, F. Cirulli, E. Alleva, R. J. Bodnar, S. R. Lewis, B. Kest, F. G. Biddle, B. A. Eales, B. Possidente, A. Holmes, R. Benno, M. E. Hahn, C. F. Plappert, P. K. D. Pilz, H. Gershenfeld, P. R. Canavello, J. M. Cachat, P. C. Hart, D. L. Murphy, A. V. Kalueff, C. Blanchard, J. Crawley, H. Arakawa, R. Blanchard, L. Niel, D. A. Monks, Abel Bult-Ito, F. Sluyter, S. de Boer, S. C. Maxson, T. J. Gould, S. F. Logue, G. Colacicco, H. Welzl, I. Branchi, L. Ricceri, Herbert Schwegler, T. P. O'Leary, R. E. Brown, E. Dere, A. Zlomuzica, M. A. De Souza Silva, J. P. Huston

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