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Endothelial Biomedicine

Endothelial Biomedicine

$389.00 (M)

Manfred D. Laubichler , William C. Aird, Jane Maienshein,Warren W. Burggren, Carl L. Reiber, J. Douglas Coffin, Kenneth R. Olson, Pavan K. Cheruvu, Daniel Gale, Ann M. Dvorak, David Haig, H. William Detrich III, José M. Icardo, Glenn J. Tattersall, Thomas J. Poole, John E. Rush, Alan R. Hargens, Knut Pettersson, Ronald W. Millard, Klaus D. Jürgens, John H. McVey Randolf M. Nesse, Alan Weder, S. Boyd Eaton, Loren Cordain, Anthony Sebastian, David Haig, Aldo Ciau-Uitz, Claire Fernandez, Roger Patient Sameer S. Chopra, Tao P. Zhong, Cam Patterson Takashi Mikawa, 22. Eckhard Lammert, Peter Lloyd Jones ,Steven Moskowitz, Kenneth L. Kaplan, Daniel L. Schodek, Dexter Pratt Helmut G. Augustin, Peter F. Davies, Gregg L. Semenza, Mitchell L. Halperin, Kamel S. Kamel, Jordan S. Pober, Debarata Mukhopadhyay, Resham Bhattacharya, Deborah A. Hughes, Xue Wang, Augustine M. K. Choi, Stefan W. Ryter, Masahiro Murakami, Arye Elfenbein, Michael Simons, Barbara J. Ballerman, Sareh Parangi, Jack Lawler, Diane Bielenberg, Peter Kurschat, Michael Klagsbrun, Helmut G. Augustin, Daniel Dumont, Kye Won Park, Lisa D. Urness, Dean Y. Li, Yasuhiro Funahashi, Carrie J. Shawber, Jan Kitajewski, Kaikobad Irani, Silvia Deaglio, Simon C. Robson, Eugene Tkachenko, John M. Rhodes, Michael Simons, Timothy Hla, Jaswinder Kaur, Paul Kubes, Jean-Luc Wautier, Ann Marie Schmidt, Anne Nicholson-Weller, Robert Colman, Kalpna Gupta, Elliot J. Stephenson, Jay W. Fox, Solange M. T. Serrano, Qing Chen, Kristen Clancy, Wan-Chao Wang, Sharon S. Evans, Bryan Belikoff, Wende R. Reenstra, Jon A. Buras, Deborah A. Quinn, Charles A. Hales, Alf O. Brubakk, Olav S. Eftedal, Ulrik Wisløff, Ulrik Wisløff, Per M. Haram, Alf O. Brubakk, Nicholas L. M. Cruden, David J. Webb, Janice V. Meck, Ralph E. Purdy, Howard D. Beall, Mark W. Majesky, Shivalika Handa, Karolina Kolodziejska, Mansoor Husain, Sruti Shiva, Mark T. Gladwin, Volker Vielhauer, Xavier Cullere, Tanya Mayadas, Patricia B. Maguire, Orina Belton, Niaobh O'Donoghue, Sandra Austin, Judith Coppinger, Jian Li, Frank W. Sellke, David Semela, Vijay Shah, Haruki Senoo Susan E. Quaggin, Michael Simons, Rolf Kinne, Ann M. Dvorak, Charles J. Lowenstein, Craig N. Morrell, Munekazu Yamakuchi, Lucy A. Carver, Jan E. Schnitzer, Radu V. Stan, Bernard M. van den Berg, Max Nieuwdorp, Erik Stroes, Hans Vink, Christopher V. Carman, Joseph H. McCarty, Richard O. Hynes, Alan S. Verkman, Xiaoqiang Yao, Ichiro Shiojima, Kenneth Wals, Natalia V. Bogatcheva, Alexander D. Verin, Alex Toker, Allan Murray, Arne Ostman, Kai Kapper, Anna Cattelino, Stefan Liebner, Kaiser M. Bijli, Arshad Rahman, Jonathan D. Brown, Jorge Plutzky, Takashi Minami, Peter Oettgen, Levon M. Khachigian, Valerie C. Midgley, Zhiyong Lin, Mukesh K. Jain, Takashi Minami, Md. Ruhul Abid, Stephen R. Archacki, Sun-Ah You, Quansheng Xi, Qing Wang, Frank Kuhnert, Heidi Stuhlmann, Neville Young, Peter Koopman, Robert Benezra, Erik Henke, Lucy A. Carver, Jan E. Schnitzer, Amado J. Zurita, Wadih Arap, Renata Pasqualini,Tom Diacovo, Alan E. Mast, Gernot Schabbauer, Nigel Mackman, Marlies Van de Wouwer, Edward M. Conway, Nicholas W. Shworak, Nicholas W. Shworak Marlies Van de Wouwer, Edward M. Conway, Bjorn Dahlback, William C. Sessa, Hong Pyo Kim, Stefan W. Ryter, Augustine M. K. Choi, Kenneth K. Wu, Joe G. N. Garcia, F. William Luscinskas, Peter J. Newman, Debra K. Newman, Rodger P. McEver, Silvia Muro, David Milstone, Elizabeth O. Harrington, Qing Lu, Sharon Rounds, Andrew H. Lichtman, Mourad Toporsian, Michelle Letarte, Christian Weidenfeller, Eric V. Shusta, Kevin J. Tracey, Christine N. Metz, Laura Benjamin, Troy Stevens, Elizabeth Wagner, Aigul Moldobaeva, Mark L. Martinez, Guy A. Zimmerman, Norbert F. Voelkel, Mark R. Nicolls, Norbert F. Voelkel, Laimute Taraseviciene-Stewart, Shampa Chatterjee, Aron B. Fisher, Myron I. Cybulsky, Laurie D. DeLeve. Winston Dunn, Vijay Shah, Ossama A. Hatoum, David G. Binion,
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  • Date Published: September 2007
  • availability: In stock
  • format: Hardback
  • isbn: 9780521853767

$389.00 (M)
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About the Authors
  • The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all reaches of the human body. Today, clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. Indeed, the endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume endeavors to bridge the bench-to-bedside gap in endothelial biomedicine, with the goal of advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. Moreover, it is unique in its interdisciplinary approach, drawing on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.

    • Employs multidisciplinary and interdisciplinary approaches to promote the endothelium as a clinically relevant organ
    • A single definitive about the endothelium at the level of the single cell, the blood vessel and the whole organism
    • Provides new insights into the endothelium as an organizing principle in health and disease
    Read more

    Reviews & endorsements

    "Dr William Aird reveals to us the landscape of this new field in his masterpiece...This comprehensive and authoritative tome is the work of many contributors, but the hand of the editor is seen in every chapter...This is an entertaining, thought-provoking, and exhaustive scholarly work. It must be read by those who aspire to become vascular biologists, and it is a useful reference for those in related fields."
    Circulation, the Journal of the American Heart Association

    "Endothelial Biomedicine is an intellectual tour de force that is a useful reference, comprehensive textbook, and thoroughly engaging work."
    Journal of the American Medical Association

    "This volume is surely the most comprehensive account of the vascular endothelium ever compiled and, as such is somewhat daunting at first inspection. However, consisting of five parts and compromising of nearly 200 separate essays, it is a tour de force and represents a very significant achievement and an invaluable resource."
    The Quarterly Review of Biology

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    Product details

    • Date Published: September 2007
    • format: Hardback
    • isbn: 9780521853767
    • length: 1894 pages
    • dimensions: 281 x 220 x 65 mm
    • weight: 4.012kg
    • contains: 81 tables
    • availability: In stock
  • Table of Contents

    Part I. Context
    Part II. Endothelial Cell as Input-Output Device
    Part III. Vascular Bed/Organ Structure and Function in Health and Disease
    Part IV. Diagnosis and Treatment
    Part V. Challenges and Opportunities.

  • Editor

    William C. Aird, Harvard University, Massachusetts
    Dr. William C. Aird received his medical degree from the University of Western Ontario in 1985. After completing his internal medicine and chief medical residency at the University of Toronto, he undertook a Hematology fellowship at the Brigham and Women's Hospital, Harvard Medical School. Dr. Aird received his postdoctoral training in the Department of Biology at the Massachusetts Institute of Technology. In 1996, he established an independent research program in the Division of Molecular Medicine at the Beth Israel Deaconess Medical Center. Dr. Aird is currently Associate Professor of Medicine at Harvard Medical School and Chief of the Division of Molecular and Vascular Medicine.

    Contributors

    Manfred D. Laubichler , William C. Aird, Jane Maienshein,Warren W. Burggren, Carl L. Reiber, J. Douglas Coffin, Kenneth R. Olson, Pavan K. Cheruvu, Daniel Gale, Ann M. Dvorak, David Haig, H. William Detrich III, José M. Icardo, Glenn J. Tattersall, Thomas J. Poole, John E. Rush, Alan R. Hargens, Knut Pettersson, Ronald W. Millard, Klaus D. Jürgens, John H. McVey Randolf M. Nesse, Alan Weder, S. Boyd Eaton, Loren Cordain, Anthony Sebastian, David Haig, Aldo Ciau-Uitz, Claire Fernandez, Roger Patient Sameer S. Chopra, Tao P. Zhong, Cam Patterson Takashi Mikawa, 22. Eckhard Lammert, Peter Lloyd Jones ,Steven Moskowitz, Kenneth L. Kaplan, Daniel L. Schodek, Dexter Pratt Helmut G. Augustin, Peter F. Davies, Gregg L. Semenza, Mitchell L. Halperin, Kamel S. Kamel, Jordan S. Pober, Debarata Mukhopadhyay, Resham Bhattacharya, Deborah A. Hughes, Xue Wang, Augustine M. K. Choi, Stefan W. Ryter, Masahiro Murakami, Arye Elfenbein, Michael Simons, Barbara J. Ballerman, Sareh Parangi, Jack Lawler, Diane Bielenberg, Peter Kurschat, Michael Klagsbrun, Helmut G. Augustin, Daniel Dumont, Kye Won Park, Lisa D. Urness, Dean Y. Li, Yasuhiro Funahashi, Carrie J. Shawber, Jan Kitajewski, Kaikobad Irani, Silvia Deaglio, Simon C. Robson, Eugene Tkachenko, John M. Rhodes, Michael Simons, Timothy Hla, Jaswinder Kaur, Paul Kubes, Jean-Luc Wautier, Ann Marie Schmidt, Anne Nicholson-Weller, Robert Colman, Kalpna Gupta, Elliot J. Stephenson, Jay W. Fox, Solange M. T. Serrano, Qing Chen, Kristen Clancy, Wan-Chao Wang, Sharon S. Evans, Bryan Belikoff, Wende R. Reenstra, Jon A. Buras, Deborah A. Quinn, Charles A. Hales, Alf O. Brubakk, Olav S. Eftedal, Ulrik Wisløff, Ulrik Wisløff, Per M. Haram, Alf O. Brubakk, Nicholas L. M. Cruden, David J. Webb, Janice V. Meck, Ralph E. Purdy, Howard D. Beall, Mark W. Majesky, Shivalika Handa, Karolina Kolodziejska, Mansoor Husain, Sruti Shiva, Mark T. Gladwin, Volker Vielhauer, Xavier Cullere, Tanya Mayadas, Patricia B. Maguire, Orina Belton, Niaobh O'Donoghue, Sandra Austin, Judith Coppinger, Jian Li, Frank W. Sellke, David Semela, Vijay Shah, Haruki Senoo Susan E. Quaggin, Michael Simons, Rolf Kinne, Ann M. Dvorak, Charles J. Lowenstein, Craig N. Morrell, Munekazu Yamakuchi, Lucy A. Carver, Jan E. Schnitzer, Radu V. Stan, Bernard M. van den Berg, Max Nieuwdorp, Erik Stroes, Hans Vink, Christopher V. Carman, Joseph H. McCarty, Richard O. Hynes, Alan S. Verkman, Xiaoqiang Yao, Ichiro Shiojima, Kenneth Wals, Natalia V. Bogatcheva, Alexander D. Verin, Alex Toker, Allan Murray, Arne Ostman, Kai Kapper, Anna Cattelino, Stefan Liebner, Kaiser M. Bijli, Arshad Rahman, Jonathan D. Brown, Jorge Plutzky, Takashi Minami, Peter Oettgen, Levon M. Khachigian, Valerie C. Midgley, Zhiyong Lin, Mukesh K. Jain, Takashi Minami, Md. Ruhul Abid, Stephen R. Archacki, Sun-Ah You, Quansheng Xi, Qing Wang, Frank Kuhnert, Heidi Stuhlmann, Neville Young, Peter Koopman, Robert Benezra, Erik Henke, Lucy A. Carver, Jan E. Schnitzer, Amado J. Zurita, Wadih Arap, Renata Pasqualini,Tom Diacovo, Alan E. Mast, Gernot Schabbauer, Nigel Mackman, Marlies Van de Wouwer, Edward M. Conway, Nicholas W. Shworak, Nicholas W. Shworak Marlies Van de Wouwer, Edward M. Conway, Bjorn Dahlback, William C. Sessa, Hong Pyo Kim, Stefan W. Ryter, Augustine M. K. Choi, Kenneth K. Wu, Joe G. N. Garcia, F. William Luscinskas, Peter J. Newman, Debra K. Newman, Rodger P. McEver, Silvia Muro, David Milstone, Elizabeth O. Harrington, Qing Lu, Sharon Rounds, Andrew H. Lichtman, Mourad Toporsian, Michelle Letarte, Christian Weidenfeller, Eric V. Shusta, Kevin J. Tracey, Christine N. Metz, Laura Benjamin, Troy Stevens, Elizabeth Wagner, Aigul Moldobaeva, Mark L. Martinez, Guy A. Zimmerman, Norbert F. Voelkel, Mark R. Nicolls, Norbert F. Voelkel, Laimute Taraseviciene-Stewart, Shampa Chatterjee, Aron B. Fisher, Myron I. Cybulsky, Laurie D. DeLeve. Winston Dunn, Vijay Shah, Ossama A. Hatoum, David G. Binion,

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