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Essential Bioinformatics

$93.99 (X)

textbook
  • Date Published: March 2006
  • availability: Available
  • format: Paperback
  • isbn: 9780521600828

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  • Essential Bioinformatics is a concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods. This balanced yet easily accessible text will be invaluable to students who do not have sophisticated computational backgrounds. Technical details of computational algorithms are explained with a minimum use of mathematical formulae; graphical illustrations are used in their place to aid understanding. The effective synthesis of existing literature as well as in-depth and up-to-date coverage of all key topics in bioinformatics make this an ideal textbook for all bioinformatics courses taken by life science students and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

    • Concise yet comprehensive and written specifically for life scientists and those without a sophisticated computational background
    • Provides annotated guides to the most frequently used internet tools for each topic and discusses the advantages of different methods
    • Includes 6 step-by-step protocols for internet-based exercises to aid student's problem-solving skills using freely available bioinformatics tools
    • Glossary provides clear definitions and easy understanding of key bioinformatics concepts and tools
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    Reviews & endorsements

    "particularly suitable for undergraduate teaching."
    Society for General Microbiology

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    Product details

    • Date Published: March 2006
    • format: Paperback
    • isbn: 9780521600828
    • length: 352 pages
    • dimensions: 254 x 177 x 21 mm
    • weight: 0.82kg
    • contains: 9 tables
    • availability: Available
  • Table of Contents

    Preface
    Part I. Introduction and Biological Databases:
    1. Introduction
    2. Introduction to biological databases
    Part II. Sequence Alignment:
    3. Pairwise sequence alignment
    4. Database similarity search
    5. Multiple sequence alignment
    6. Profiles and hidden Markov models
    7. Protein motifs and patterns
    Part III. Gene and Promoter Prediction:
    8. Gene prediction
    9. Promoter and regulatory element prediction
    Part IV. Molecular Phylogenetics:
    10. Phylogenetics basics
    11. Phylogenetic tree construction methods and programs
    Part V. Protein Structure Basics:
    12. Protein structure basics
    13. Protein structure visualization, comparison and classification
    14. Protein secondary structure prediction
    15. Protein tertiary structure prediction
    16. RNA structure prediction
    Part VI. Genomics and Proteomics:
    17. Genome mapping, assembly and comparison
    18. Functional genomics
    19. Proteomics
    Practical exercises
    Glossary.

  • Resources for

    Essential Bioinformatics

    Jin Xiong

    General Resources

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    These resources are provided free of charge by Cambridge University Press with permission of the author of the corresponding work, but are subject to copyright. You are permitted to view, print and download these resources for your own personal use only, provided any copyright lines on the resources are not removed or altered in any way. Any other use, including but not limited to distribution of the resources in modified form, or via electronic or other media, is strictly prohibited unless you have permission from the author of the corresponding work and provided you give appropriate acknowledgement of the source.

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  • Instructors have used or reviewed this title for the following courses

    • Advance topics in Biology
    • Bioinformatics
    • Introduction to Bioinformatics
    • functional genomics
  • Author

    Jin Xiong, Texas A & M University
    Jin Xiong is Assistant Professor of Biology at Texas A & M University, where he has taught bioinformatics to graduate and undergraduate students for several years.

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