Other available formats:
Looking for an examination copy?
If you are interested in the title for your course we can consider offering an examination copy. To register your interest please contact firstname.lastname@example.org providing details of the course you are teaching.
Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard Ø. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dynamic models using metabolomic and fluxomic data. The Mass Action Stoichiometric Simulation (MASS) procedure can be used for any cellular process for which data is available and allows a scalable step-by-step approach to the practical construction of network models. Specifically, it can treat integrated processes that need explicit accounting of small molecules and protein, which allows simulation at the molecular level. The material has been class-tested by the author at both the undergraduate and graduate level. All computations in the text are available online in MATLAB and MATHEMATICA® workbooks, allowing hands-on practice with the material.Read more
- Shows how dynamic models are built and simulated in the modern omics era
- Provides a unified framework that allows the treatment of metabolites, enzymes and binding protein simultaneously
- Material for instructors and students is available from http://systemsbiology.ucsd.edu
Not yet reviewed
Be the first to review
Review was not posted due to profanity×
- Date Published: June 2011
- format: Hardback
- isbn: 9781107001596
- length: 332 pages
- dimensions: 254 x 182 x 25 mm
- weight: 0.8kg
- contains: 126 b/w illus.
- availability: Available
Table of Contents
2. Basic concepts
Part I. Simulation of Dynamic States:
3. Dynamic simulation: the basic procedure
4. Chemical reactions
5. Enzyme kinetics
6. Open systems
Part II. Biological Characteristics:
7. Orders of magnitude
8. Stoichiometric structure
9. Regulation as elementary phenomena
Part III. Metabolism:
11. Coupling pathways
12. Building networks
Part IV. Macromolecules:
14. Regulated enzymes
B. Homework problems
Welcome to the resources site
Here you will find free-of-charge online materials to accompany this book. The range of materials we provide across our academic and higher education titles are an integral part of the book package whether you are a student, instructor, researcher or professional.
Find resources associated with this titleYour search for '' returned .
Type Name Unlocked * Format Size
*This title has one or more locked files and access is given only to instructors adopting the textbook for their class. We need to enforce this strictly so that solutions are not made available to students. To gain access to locked resources you either need first to sign in or register for an account.
These resources are provided free of charge by Cambridge University Press with permission of the author of the corresponding work, but are subject to copyright. You are permitted to view, print and download these resources for your own personal use only, provided any copyright lines on the resources are not removed or altered in any way. Any other use, including but not limited to distribution of the resources in modified form, or via electronic or other media, is strictly prohibited unless you have permission from the author of the corresponding work and provided you give appropriate acknowledgement of the source.
If you are having problems accessing these resources please email email@example.com
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email firstname.lastname@example.orgRegister Sign in
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.Continue ×