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Dendritic Cell Interactions with Bacteria

Dendritic Cell Interactions with Bacteria

$172.00 (C)

Part of Advances in Molecular and Cellular Microbiology

Carlos Ardavín, Osamu Takeuchia, Shizuo Akira, Laurence Bougnères-Vermont, Pierre Guermonprez, Maria Rescigno, Natalya V. Serbina Eric G. Pamer, Guido Ferlazzo, Sunny Shin, Catarina Nogueira, Craig R. Roy, Mary Jo Wick, Anneke Engering, Sandra J. van Vliet, Estella A. Koppel, Teunis B. H. Geijtenbeek, Yvette van Kooyk, Miriam T. Brady, Peter McGuirk, Kingston H. G. Mills, Christopher Becker
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  • Date Published: May 2007
  • availability: In stock
  • format: Hardback
  • isbn: 9780521855860

$ 172.00 (C)
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  • Emerging evidence suggests that dendritic cells play a major role in the orchestration of the immune response to bacteria. This volume introduces the reader to the complex world of dendritic cells and describes how the intimate interplay between dendritic cells, bacteria and the environment dictates either the induction of immunity or tolerance to the encountered microorganisms. It discusses how this can allow organisms to tolerate beneficial bacteria and to react against pathogens, as well as the strategies pathogenic bacteria have evolved to escape dendritic cell patrolling. Expert contributors discuss everything from bacterial capture and recognition to their killing, processing and the induction of adaptive immunity. Particular focus is on the tissue context in which bacteria are handled by dendritic cells and on possible defects therein, which may potentially lead to chronic infection or inflammation. Graduate students and researchers will find this an invaluable overview of current dendritic cell biology research.

    • Topic of great interest among microbiologists and immunologists as dendritic cells are the key to how organisms can tolerate beneficial bacteria and react against invading pathogens
    • Includes an introductory section on the biology of dendritic cells to allow readers to gain a thorough understanding of subsequent chapters
    • Chapters cover the very latest research findings in the field to provide students and researchers with an accessible update and overview
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    Product details

    • Date Published: May 2007
    • format: Hardback
    • isbn: 9780521855860
    • length: 266 pages
    • dimensions: 235 x 160 x 20 mm
    • weight: 0.565kg
    • contains: 9 b/w illus. 4 colour illus.
    • availability: In stock
  • Table of Contents

    Preface
    Part I. Dendritic Cells and Their Role in Immunity:
    1. Sub-populations and differentiation of mouse dendritic cells Carlos Ardavín
    2. Toll-like receptor signalling Osamu Takeuchia and Shizuo Akira
    3. MHC class I & II pathways for presentation and cross presentation of bacterial antigens Laurence Bougnères-Vermont and Pierre Guermonprez
    Part II. Dendritic Cells and Innate Immune Responses to Bacteria:
    4. Dendritic cell activation and uptake of bacteria in vivo Maria Rescigno
    5. Role of dendritic cells in the innate response to bacteria Natalya V. Serbina and Eric G. Pamer
    6. Interactions between natural killer and dendritic cells during bacterial infections Guido Ferlazzo
    Part III. Dendritic Cells and Adaptive Immune Response to Bacteria:
    7. Peculiar ability of dendritic cells to process and present antigens from vacuolar pathogens: a lesson from Legionella Sunny Shin, Catarina Nogueira and Craig R. Roy
    8. Dendritic cells, macrophages and cross-presentation of bacterial antigens: a lesson from Salmonella Mary Jo Wick
    Part IV. Dendritic Cells and Immune Evasion of Bacteria in vivo:
    9. Pathogen-recognition receptors as targets for pathogens to modulate immune function of antigen presenting cells Anneke Engering, Sandra J. van Vliet, Estella A. Koppel, Teunis B. H. Geijtenbeek and Yvette van Kooyk
    10. Suppression of immune responses by bacteria and their products through dendritic cell modulation and regulatory T cell induction Miriam T. Brady, Peter McGuirk and Kingston H. G. Mills
    11. Dendritic cells in the gut and their possible role in the pathogenesis of inflammatory bowel diseases Christopher Becker.

  • Editor

    Maria Rescigno, European Institute of Oncology, Milan
    Maria Rescigno is the Director of the Research Unit at the European Institute of Oncology, Italy. The research focuses on the study of dendritic cell biology and immunotherapy.

    Contributors

    Carlos Ardavín, Osamu Takeuchia, Shizuo Akira, Laurence Bougnères-Vermont, Pierre Guermonprez, Maria Rescigno, Natalya V. Serbina Eric G. Pamer, Guido Ferlazzo, Sunny Shin, Catarina Nogueira, Craig R. Roy, Mary Jo Wick, Anneke Engering, Sandra J. van Vliet, Estella A. Koppel, Teunis B. H. Geijtenbeek, Yvette van Kooyk, Miriam T. Brady, Peter McGuirk, Kingston H. G. Mills, Christopher Becker

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