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Kinetics for the Life Sciences
Receptors, Transmitters and Catalysts

$108.00 (P)

  • Date Published: September 1995
  • availability: Available
  • format: Paperback
  • isbn: 9780521485869

$ 108.00 (P)
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About the Authors
  • This book introduces the reader to the kinetic analysis of a wide range of biological processes at the molecular level. It shows that the same approach can be used to resolve the number of steps for a wide range of systems including enzyme reactions, muscle contraction, visual perception, and ligand binding. The author discusses the methods for characterizing these steps in chemical terms. Firmly rooted in theory, a wide range of examples and experimental techniques are introduced as well. A historical approach is used to demonstrate the development of the theory and experimental techniques of kinetic analysis in biology.

    • Well-known author
    • The only current book giving a general analysis of a wide range of biological problems where biological kinetics can be usefully applied
    • Written for the graduate student
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    Reviews & endorsements

    "Gutfreund, who has enjoyed a long and distinguished career in biochemical kinetics, writes quite elegantly here....Well written, clearly illustrated, and easily readable for the technically versed." Choice

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    Product details

    • Date Published: September 1995
    • format: Paperback
    • isbn: 9780521485869
    • length: 360 pages
    • dimensions: 229 x 152 x 20 mm
    • weight: 0.53kg
    • contains: 51 b/w illus. 8 tables
    • availability: Available
  • Table of Contents

    Part I. The Time Scales of Nature: a Historical Survey:
    1. The history of the application of physical principles
    2 Kinetics and biological problems
    3 Time scales of nature and of measurement
    Part II. Some Mathematical Introductions:
    4. The origins of exponential behaviour
    5. Modelling of kinetic systems
    6. Data collection, reduction and analysis
    7. Guidelines for the derivation of equations used in the text
    Part III. Elementary Kinetic Equations: Ground Rules:
    8. The law of mass action, rates and equilibria
    9. The evaluation of first and second order rate constants
    10. An introduction to practical steady state kinetics
    11. Steady state kinetics of reversible effectors and ionic equilibria
    Part IV. Kinetic Analysis of Complex Reactions:
    12. Introduction to the study of transients and reaction sequences
    13. Consecutive reactions and physiological responses
    Part V. Kinetic Mechanisms of Enzyme Reactions:
    14. Transient kinetics and enzyme reactions
    15. Sequential enzyme reactions in metabolism and control
    16. Kinetics of ligand dissociation and exchange between binding sites
    Part VI. Chemical Relaxation Phenomena:
    17. Applications of relaxation kinetics
    18. Basic equations for the analysis of chemical relaxations
    19. Chemical relaxation of ligand binding and recognition
    20. Relaxations of proton equilibria
    PartVII. Factors Affecting the Rates of Chemical Reactions
    21. Introduction to the history and concepts of chemical dynamics
    22. Temperature dependence of reactions and the activation parameters
    23. Viscosity and molecular dynamics
    24. Diffusion control of reactions
    25. Some comments on the use of isotopes in kinetic investigations
    Part VIII. The Role of Light in Kinetic Investigations
    26. Applications of photochemistry
    27. Luminescence and other excited states
    28. The scope of fluorescence life time studies
    29. Photolabile (caged) compounds for the initiation of reactions
    References
    Index.

  • Author

    H. Gutfreund, University of Bristol

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