Skip to content
Open global navigation

Cambridge University Press

AcademicLocation selectorSearch toggleMain navigation toggle
Cart
Register Sign in Wishlist

Inflammatory Diseases of the Central Nervous System

$136.00

Edgar Meinl, Hartmut Wekerle, Bevyn Jarrott, Karina Apricò, Heather Donaghy, Edwina J. Wright, Anthony L. Cunningham, Britta Engelghardt, Shaunu F. Roemer, Claudia F. Lucchinetti, Martin Kerschensteiner, Reinhard Hohlfeld, Lisa Walter, Matthew L. Albert, Eppie M. Yiu, Andrew J. Kornberg, Tina Chadha, George F. Duna, Leonard H. Calabrese, David N. Irani, Natalie Prow, Carolyn F. Orr, Bruce J. Brew, Trine H. Mogensen, Lars Østergaard, Stephen J. Rogerson, Danny A. Milner Jr, Cristina Morganti-Kossmann, Laveniya Satgunaseelan, Nicole Bye, Phuong Nguyen, Thomas Kossmann, Nicoline Schiess, Justin C. McArthur, Miles H. Beaman, Joseph M. Antony, Christopher Power
View all contributors
  • Date Published: November 2009
  • availability: In stock
  • format: Hardback
  • isbn: 9780521888745

$136.00
Hardback

Add to cart Add to wishlist

Looking for an examination copy?

This title is not currently available for examination. However, if you are interested in the title for your course we can consider offering an examination copy. To register your interest please contact collegesales@cambridge.org providing details of the course you are teaching.

Description
Product filter button
Description
Contents
Resources
About the Authors
  • Interactions between the immune and nervous systems are involved in many disease processes. Modulation of inflammation can provide an important opportunity to enhance regeneration within the central nervous system. This authoritative book defines the key cellular players in mounting an inflammatory response and highlights critical factors in the target organ that influence the nature of that response and its capacity either to damage or protect the brain. Several key clinical areas are highlighted – particularly autoimmune diseases of the nervous system including multiple sclerosis, as well as microbiological and traumatic challenges; the book therefore provides both a summary of the basic science background as well as practical, clinical-friendly guidelines to management. The book will be of interest to a wide range of physicians, including neurologists, neurosurgeons, neurorehabilitationists, infectious disease physicians, and clinical neuroscientists, as well as neuroscientists and immunologists.

    • Reviews diseases involving interactions between the nervous and immunological systems a complex area: text explains basic science in a clinician-friendly manner
    • Coverage includes major areas of neurology, e.g. multiple sclerosis, neurological infections, trauma therefore wide readership potential
    • Therapeutic management of inflammation covered practical clinical advice on how to manage inflammatory conditions
    • Rehabilitation aspects included great interest in how modulation of inflammation can stimulate neurological function and aid recovery
    Read more

    Customer reviews

    Not yet reviewed

    Be the first to review

    Review was not posted due to profanity

    ×

    , create a review

    (If you're not , sign out)

    Please enter the right captcha value
    Please enter a star rating.
    Your review must be a minimum of 12 words.

    How do you rate this item?

    ×

    Product details

    • Date Published: November 2009
    • format: Hardback
    • isbn: 9780521888745
    • length: 282 pages
    • dimensions: 252 x 193 x 18 mm
    • weight: 0.8kg
    • contains: 6 b/w illus. 13 colour illus. 16 tables
    • availability: In stock
  • Table of Contents

    Preface
    Part I. Interactions Between the Immune and Nervous Systems:
    1. Effectors and determinants of the innate and adaptive immune responses Edgar Meinl and Hartmut Wekerle
    2. Microglia: protective and pathogenic mediators Bevyn Jarrott and Karina Apricò
    3. The role of dendritic cells in neuroinflammation Heather Donaghy, Edwina J. Wright and Anthony L. Cunningham
    4. Negotiating the brain barriers: access of immune cells and pathogens into the CNS Britta Engelghardt
    Part II. Autoimmunity:
    5. Immune effector heterogeneity in multiple sclerosis and related CNS inflammatory demyelinating disorders Shaunu F. Roemer and Claudia F. Lucchinetti
    6. Multiple sclerosis: neuroimmune crosstalk in acute and progressive stages of the disease Martin Kerschensteiner and Reinhard Hohlfeld
    7. CD8+ T Cell-mediated autoimmune diseases in the CNS Lisa Walter and Matthew L. Albert
    8. Acute disseminated encephalomyelitis: determinants and manifestations Eppie M. Yiu and Andrew J. Kornberg
    9. Primary angiitis of the CNS and its mimics Tina Chadha, George F. Duna and Leonard H. Calabrese
    Part III. Microbiological and Traumatic Challenges to the CNS:
    10. Acute viral encephalitis: role of the immune system in viral clearance from the CNS and in the generation of pathology David N. Irani and Natalie Prow
    11. Chronic HIV infection of the CNS: role of the immune system in virological control and the generation of pathology Carolyn F. Orr and Bruce J. Brew
    12. Brain inflammation during bacterial meningitis Trine H. Mogensen and Lars Østergaard
    13. Parasitic infections of the brain: malaria and beyond Stephen J. Rogerson and Danny A. Milner Jr
    14. Role of the inflammatory process in traumatic brain damage Cristina Morganti-Kossmann, Laveniya Satgunaseelan, Nicole Bye, Phuong Nguyen and Thomas Kossmann
    Part IV. Therapy:
    15. HIV-associated neurocognitive disorders: clinical features and therapeutic challenges Nicoline Schiess and Justin C. McArthur
    16. Role of immunomodulation in management of infections of the CNS Miles H. Beaman
    17. Neuroinflammation: an emerging therapeutic target in neurological disease Joseph M. Antony and Christopher Power
    Index.

  • Editors

    Trevor Kilpatrick, Centre for Neuroscience, University of Melbourne
    Trevor Kilpatrick is Professor of Neurology and Director of the Centre for Neuroscience at the University of Melbourne, leader of the MS Group at the Howard Florey Institute and Neurologist and Head of the MS Unit at the Royal Melbourne Hospital.

    Richard M. Ransohoff, Cleveland Clinic Foundation
    Richard M. Ransohoff is Director of the Neuroinflammation Research Center in the Department of Neurosciences at the Lerner Research Institute, Cleveland Clinic; Professor of Molecular Medicine at the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University; and Staff Neurologist in the Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, Ohio.

    Steven Wesselingh, Monash University, Victoria
    Steven Wesselingh is Professor of Microbiology and Medicine, Monash University, Melbourne.

    Contributors

    Edgar Meinl, Hartmut Wekerle, Bevyn Jarrott, Karina Apricò, Heather Donaghy, Edwina J. Wright, Anthony L. Cunningham, Britta Engelghardt, Shaunu F. Roemer, Claudia F. Lucchinetti, Martin Kerschensteiner, Reinhard Hohlfeld, Lisa Walter, Matthew L. Albert, Eppie M. Yiu, Andrew J. Kornberg, Tina Chadha, George F. Duna, Leonard H. Calabrese, David N. Irani, Natalie Prow, Carolyn F. Orr, Bruce J. Brew, Trine H. Mogensen, Lars Østergaard, Stephen J. Rogerson, Danny A. Milner Jr, Cristina Morganti-Kossmann, Laveniya Satgunaseelan, Nicole Bye, Phuong Nguyen, Thomas Kossmann, Nicoline Schiess, Justin C. McArthur, Miles H. Beaman, Joseph M. Antony, Christopher Power

Sign In

Please sign in to access your account

Cancel

Not already registered? Create an account now. ×

You are now leaving the Cambridge University Press website, your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.

Continue ×

Continue ×

Find content that relates to you

© Cambridge University Press 2014

Back to top

Are you sure you want to delete your account?

This cannot be undone.

Cancel Delete

Thank you for your feedback which will help us improve our service.

If you requested a response, we will make sure to get back to you shortly.

×
Please fill in the required fields in your feedback submission.
×