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Vascular Cognitive Impairment in Clinical Practice

$164.99

Timo Erkinjuntti, Serge Gauthier, Adriane Mayda, Charles DeCarli, Oscar L. Lopez, David A. Wolk, Erika J. Laukka, Sari Karlsson, Stuart W. S. MacDonald, Lars Bäckman, Wiesje M. van der Flier, Salka S. Staekenborg, Frederik Barkhof, Philip Scheltens, Lars-Olof Wahlund, Rimma Axelsson, Anders Wallin, Tuula Pirttilä, Leonardo Pantoni, Francesca Pescini, Anna Poggesi, Raj N. Kalaria, Franz Fazekas, Christian Enzinger, Stefan Ropele, Reinhold Schmidt, Agueda Rostagno, Jorge Ghiso, Chengxuan Qiu, Laura Fratiglioni, Angela L. Jefferson, Emelia J. Benjamin, Miia Kivipelto, Alina Solomon, Tiia Ngandu, Lena Borell, Catherine Cole, Alistair Burns, Deborah Gustafson, Ingmar Skoog
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  • Date Published: February 2009
  • availability: In stock
  • format: Hardback
  • isbn: 9780521875370

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About the Authors
  • Vascular cognitive impairment is the second most common cause of dementia after Alzheimer's disease and is expected to grow in prevalence with the aging global population. The purpose of this authoritative book is to give a broad clinical perspective on vascular cognitive impairment and thus create a foundation for the implementation of good dementia care. The book focuses on pathophysiology, diagnosis, treatment and prevention. It demonstrates the underlying causes of the disorder, such as the manner in which vascular risk-factors influence the onset of vascular cognitive impairment. The concept of mixed forms of vascular dementia, Alzheimer's dementia and other vascular diseases is discussed as well as the influence of vascular changes with regard to the onset of Alzheimer's disease. The detailed section on pathophysiology will enhance clinicians' understanding of this complex disorder. Finally there is a section on pharmacological and neuropsychological treatment of cognitive and psychiatric symptoms.

    • Presents detailed information on treatment - practical advice on the management of patients with vascular cognitive impairment
    • Discusses the scientific background of vessel-dependent cognitive impairment - gives the reader insight into how vascular disease affects cognitive functioning
    • Advises the reader on how to use the most modern imaging devices as well as neuropsychological and neurochemical techniques to diagnose vascular dementia
    • Presents pharmacological and non-pharmacological treatment of cognitive and psychiatric symptoms
    Read more

    Reviews & endorsements

    "This multiauthored monograph chronicles how changes in brain blood vessels affect cognition and cause dementia and other related syndromes. It is a brilliant synthesis of a complicated topic, drawing together knowledge and recent discoveries from a wide variety of disciplines....This is a major contribution to the field. It sorts out in clear fashion a very tangled literature. In the process, it points out just where future research is needed. Methodological issues of such research and the profound implications of epidemiological studies (vascular disease starts early and causes cognitive changes in midlife) are emphasized. In addition, the book provides clear outlines of the approach to differential diagnosis and management of these patients, including caregiver support. Finally, the links of heart disease to both vascular cognitive impairment and Alzheimer's disease are discussed. The excellent organization and editing of this book, its careful elaboration of complex concepts, and the practical application of this synthesis give rise to a first-rate work. This much-needed book deserves a wide readership."
    --Doody's Review Service

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    Product details

    • Date Published: February 2009
    • format: Hardback
    • isbn: 9780521875370
    • length: 254 pages
    • dimensions: 252 x 192 x 13 mm
    • weight: 0.71kg
    • contains: 17 b/w illus. 5 colour illus. 25 tables
    • availability: In stock
  • Table of Contents

    List of contributors
    Preface
    Part I. Diagnosis:
    1. Diagnosing vascular cognitive impairment and dementia – concepts and controversies Timo Erkinjuntti and Serge Gauthier
    2. Vascular cognitive impairment - prodrome to VaD? Adriane Mayda and Charles DeCarli
    3. Clinical evaluation: a systematic but user-friendly approach Oscar L. Lopez and David A. Wolk
    4. Cognitive functioning in vascular dementia before and after diagnosis Erika J. Laukka, Sari Karlsson, Stuart W. S. MacDonald and Lars Bäckman
    5. Structural neuroimaging: CT and MRI Wiesje M. van der Flier, Salka S. Staekenborg, Frederik Barkhof and Philip Scheltens
    6. Functional imaging in vascular dementia – clinical practice Lars-Olof Wahlund and Rimma Axelsson
    7. Biomarkers in vascular dementia Anders Wallin and Tuula Pirttilä
    Part II. Pathophysiology:
    8. Physio-pathology of large vessel vascular dementia Leonardo Pantoni, Francesca Pescini and Anna Poggesi
    9. Small vessel diseases of the brain Raj N. Kalaria and Timo Erkinjuntti
    10. White matter changes Franz Fazekas, Christian Enzinger, Stefan Ropele and Reinhold Schmidt
    11. Hereditary forms of cerebrovascular amyloidosis Agueda Rostagno and Jorge Ghiso
    12. Role of vascular risk factors in dementia Chengxuan Qiu and Laura Fratiglioni
    13. Cardiovascular disease, cognitive decline, and dementia Angela L. Jefferson and Emelia J. Benjamin
    14. Vascular factors in Alzheimer's disease: from diagnostic dichotomy to integrative etiology Miia Kivipelto, Alina Solomon and Tiia Ngandu
    Part III. Treatment:
    15. Treatment of cognitive changes Serge Gauthier and Timo Erkinjuntti
    16. Treatment of functional decline Lena Borell
    17. Treatment of behavioral symptoms in vascular dementia Catherine Cole and Alistair Burns
    18. Control of vascular risk factors Deborah Gustafson and Ingmar Skoog
    Index.

  • Editors

    Lars-Olof Wahlund, Karolinska Institutet, Stockholm
    Lars-Olof Wahund is a Professor at the Department of Neurobiology, Caring Sciences and Society at the Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden.

    Timo Erkinjuntti, University of Helsinki
    Timo Erkinjuntti is Professor of Neurology at the Department of Neurology, University of Helsinki, Helsinki, Finland.

    Serge Gauthier, McGill University, Montréal
    Serge Gauthier is a Professor and Director at the Alzheimer's Disease and Related Disorders Research Unit, McGill Centre for Studies on Aging, Douglas Mental Health University Institute, Montréal, Québec, Canada.

    Contributors

    Timo Erkinjuntti, Serge Gauthier, Adriane Mayda, Charles DeCarli, Oscar L. Lopez, David A. Wolk, Erika J. Laukka, Sari Karlsson, Stuart W. S. MacDonald, Lars Bäckman, Wiesje M. van der Flier, Salka S. Staekenborg, Frederik Barkhof, Philip Scheltens, Lars-Olof Wahlund, Rimma Axelsson, Anders Wallin, Tuula Pirttilä, Leonardo Pantoni, Francesca Pescini, Anna Poggesi, Raj N. Kalaria, Franz Fazekas, Christian Enzinger, Stefan Ropele, Reinhold Schmidt, Agueda Rostagno, Jorge Ghiso, Chengxuan Qiu, Laura Fratiglioni, Angela L. Jefferson, Emelia J. Benjamin, Miia Kivipelto, Alina Solomon, Tiia Ngandu, Lena Borell, Catherine Cole, Alistair Burns, Deborah Gustafson, Ingmar Skoog

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