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Developmental Origins of Health and Disease

$247.00

Peter D. Gluckman, Mark A. Hanson, Keith Godfrey, Tom P. Fleming, Emma Whitelaw, David Garrick, Josie M. L .McConnell, Jerrold J. Heindel, Cindy Lawler, Susan M. B. Morton, Leslie Myatt, Victoria Roberts, Abigail L. Fowden, Janelle W. Ward, Alison J. Forhead, Graham C. Burdge, Philip C. Calder, Dino A. Giussani, Deborah M. Sloboda, John P. Newnham, Timothy J. M. Moss, John R. G. Challis, Wayne S. Cutfield, Carl A. Jefferies, Paul L. Hofman, Johan G. Eriksson, Brigitte Reusens, Luise Kalbe, Claude Remacle, Noel H. Smith, Susan E. Ozanne, Michael E. Symonds, David S. Gardner, Christopher D. Byrne, David I. W. Phillips, Kent L. Thornburg, Lucilla Poston, Christopher Torrens, James Armitage, Mark Hanson, Claudio Napoli, Orlando Pignalosa, Loredana Rossi, C. Botti, Carmen Guarino, Vincenzo Sica, Filomena de Nigris, Karen M. Moritz, E. Marelyn Wintour, Miodrag Dodic, Mostafa A. El-Haddad, Michael G. Ross, Richard Harding, Megan L. Cock, Gert S. Maritz, John O. Warner, Jason Landon, Michael Davison, Bernhard H. Breier, Sandra Rees, Richard Harding,Terrie Inder, Cyrus Cooper, Avan Aihie Sayer, Elaine Margaret Dennison, Richard O. C. Oreffo, Helmtrud I. Roach, Anders Ekbom, Thomas B. L. Kirkwood, Terrence Forrester, Catherine Law, Janis Baird, Caroline H. D. Fall, Harshpal Singh Sachdev, Ray Noble
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  • Date Published: May 2006
  • availability: Temporarily unavailable - no date available
  • format: Hardback
  • isbn: 9780521847438

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About the Authors
  • This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.

    • Links early development to the onset of many chronic diseases such as coronary heart disease, diabetes and osteoporosis
    • Explains concepts, possible mechanisms, outcomes and public health consequences
    • A definitive account of a rapidly emerging area
    • Authors of the The Fetal Matrix: Evolution, Development and Disease
    Read more

    Reviews & endorsements

    "They certainly provide us with food for thought....This text is intended for...one with interest and expertise in all of the various scientific fields that are involved in the examination of the variables that influence human development, especially as it pertains to the onset of chronic diseases. Students, clinicians, and researchers will benefit from this up-to-date accounting of the current knowledge in DOHaD...This book is, foremost, a textbook useful for upper level or graduate coursework and as a reference tool for practitioners."
    John S. Wodarski, Contemporary Psychology: APA Review of Books

    "Researchers will find Developmental Origins of Health and Disease to be a well-referenced resource that documents the state of the art in the field and serves as a source of new ideas." Linda Adair, Science

    Editors Peter Gluckman and Mark Hanson have assembled many of the world's leading experts to write chapters for this volume, which is now a state-of-the-art book for this field."
    Matthew W. Gilman, JAMA

    "The volume' extensive list of contributors (seventy-four) not only represents the lion's share of DOHaD's current leading researchers, but some of the field's original founders, including one of its patriarchs, David J.P. Barker. As a result, the reader is exposed to the field's best and brightest, and overall, it shows in the content and writing."
    Daniel C. Benyshek, American Journal of Human Biology

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    Product details

    • Date Published: May 2006
    • format: Hardback
    • isbn: 9780521847438
    • length: 542 pages
    • dimensions: 254 x 191 x 29 mm
    • weight: 1.306kg
    • contains: 81 b/w illus. 6 colour illus.
    • availability: Temporarily unavailable - no date available
  • Table of Contents

    1. The developmental origins of health and disease: an overview
    2. The 'developmental origins' hypothesis: epidemiology
    3. The conceptual basis for the developmental origins of health and disease
    4. The periconceptional and embryonic period
    5. Epigenetic mechanisms
    6. A mitochondrial component of developmental programming
    7. Role of exposure to environmental chemicals in developmental origins of health and disease
    8. Maternal nutrition and fetal growth and development
    9. Placental mechanisms and developmental origins of health and disease
    10. Control of fetal metabolism: relevance to developmental origins of health and disease
    11. Lipid metabolism: relevance to developmental origins of health and disease
    12. Prenatal hypoxia: relevance to developmental origins of health and disease
    13. The fetal hypothalamic-pituitary-adrenal axis: relevance to developmental origins of health and disease
    14. Perinatal influences on the endocrine and metabolic axes during childhood
    15. Developmental origins of health and disease: relevance of patterns of growth
    16. The developmental environment and the endocrine pancreas
    17. The develop
    28. The developmental environment and the origins of neurological disorders mental environment and insulin resistance
    18. The developmental environment and the development of obesity
    19. The developmental environment and its role in the metabolic syndrome
    20. Programming the cardiovascular system
    21. The role of vascular dysfunction in developmental
    22. The developmental environment and atherogenesis origins of health and disease: evidence from studies in man and animals
    23. The developmental environment, renal function and disease
    24. The developmental environment: effect on fluid and electrolyte homeostasis
    25. The developmental environment: effects on lung structure and function
    26. Developmental origins of asthma and related allergic disorders
    27. The developmental environment: Influences on subsequent cognitive function and behaviour
    28. The developmental environment and the origins of neurological disorders
    29. The developmental environment: clinical perspectives on effects on the musculoskeletal system
    30. The developmental environment: experimental perspectives on skeletal development
    31. The developmental environment and the early origins of cancer
    32. The developmental environment: implications for aging and lifespan
    33. Developmental origins of health and disease: implications for primary intervention for cardiovascular and metabolic disease
    34. Developmental origins of health and disease: public health perspectives
    35. Developmental origins of health and disease: implications for developing countries
    36. Developmental origins of health and disease: ethical and social considerations.

  • Editors

    Peter Gluckman, University of Auckland

    Mark Hanson, University of Southampton

    Contributors

    Peter D. Gluckman, Mark A. Hanson, Keith Godfrey, Tom P. Fleming, Emma Whitelaw, David Garrick, Josie M. L .McConnell, Jerrold J. Heindel, Cindy Lawler, Susan M. B. Morton, Leslie Myatt, Victoria Roberts, Abigail L. Fowden, Janelle W. Ward, Alison J. Forhead, Graham C. Burdge, Philip C. Calder, Dino A. Giussani, Deborah M. Sloboda, John P. Newnham, Timothy J. M. Moss, John R. G. Challis, Wayne S. Cutfield, Carl A. Jefferies, Paul L. Hofman, Johan G. Eriksson, Brigitte Reusens, Luise Kalbe, Claude Remacle, Noel H. Smith, Susan E. Ozanne, Michael E. Symonds, David S. Gardner, Christopher D. Byrne, David I. W. Phillips, Kent L. Thornburg, Lucilla Poston, Christopher Torrens, James Armitage, Mark Hanson, Claudio Napoli, Orlando Pignalosa, Loredana Rossi, C. Botti, Carmen Guarino, Vincenzo Sica, Filomena de Nigris, Karen M. Moritz, E. Marelyn Wintour, Miodrag Dodic, Mostafa A. El-Haddad, Michael G. Ross, Richard Harding, Megan L. Cock, Gert S. Maritz, John O. Warner, Jason Landon, Michael Davison, Bernhard H. Breier, Sandra Rees, Richard Harding,Terrie Inder, Cyrus Cooper, Avan Aihie Sayer, Elaine Margaret Dennison, Richard O. C. Oreffo, Helmtrud I. Roach, Anders Ekbom, Thomas B. L. Kirkwood, Terrence Forrester, Catherine Law, Janis Baird, Caroline H. D. Fall, Harshpal Singh Sachdev, Ray Noble

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