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Liver Disease in Children

4th Edition

$184.00 ( ) USD

Yiwei Zong, Joshua R. Friedman, Frederick J. Suchy, Nitika A. Gupta, Saul J. Karpen, Robert H. Squires, Estella M. Alonso, Evelyn K. Hsu, Karen F. Murray, Benjamin L. Shneider, Vicky Lee Ng, Amy Feldman, Andrew P. Feranchak, Ronald J. Sokol, Philip Rosenthal, William F. Balistreri, Jorge A. Bezerra, Frederick C. Ryckman, Mark Bartlett, Glenn R. Gourley, Shikha S. Sundaram, Binita M. Kamath, Nancy B. Spinner, David A. Piccoli, Jason Soden, Frank W. DiPaola, James E. Heubi, Mei-Hwei Chang, Maureen M. Jonas, Nanda Kerkar, Cara L. Mack, Alexander G. Miethke, Eve A. Roberts, Nedim Hadžić, Piero Rinaldo, David H. Perlmutter, Meghana Sathe, Rana F. Ammoury, Fayez K. Ghishan, Michael R. Narkewicz, Peter F. Whittington, Robert J. Desnick, Manisha Balwani, Karl E. Anderson, Grant Mitchell, Pierre A. Russo, Josée Dubois, Fernando Alvarez, T. Andrew Burrow, Gregory A. Grabowski, Kenneth D. R. Setchell, Melanie B. Gillingham, Robert B. Steiner, Rohit Kohli, Kevin E. Bove, Stavra A. Xanthakos, Paul A. Watkins, Kathleen B. Schwarz, Derek Wong, Stephen Cederbaum, Donald A. Novak, Gregory Y. Lauwers, Richard L. Kradin, Kathleen M. Campbell, Ronen Arnon, Antonio R. Perez-Atayde, Dolores López-Terrada, Milton J. Finegold, M. Kyle Jensen, Maria H. Alonso, Jaimie D. Nathan, Gregory M. Tiao, Riccardo A. Superina
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  • The fourth edition of this authoritative text covers every aspect of liver disease affecting infants, children and adolescents. As in the previous editions, it offers an integrative approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. All of the chapters are written by international experts and address the unique pathophysiology, manifestations and management of these disorders. This edition of the landmark text features extended coverage of viral hepatitis, metabolic liver disease, fatty liver disease and liver transplantation, including a new chapter on post-transplant care and outcomes. All of the chapters have been updated to reflect changing epidemiology and recent advances in molecular medicine and genomics. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

    • Comprehensively covers every aspect of pediatric liver disease including current approaches to diagnosis and treatment
    • Fully updated to reflect recent advances in molecular medicine and genomics
    • New edition features extended coverage of viral hepatitis, metabolic liver disease, fatty liver disease and liver transplantation
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    Product details

    • Edition: 4th Edition
    • format: Adobe eBook Reader
    • isbn: 9781107722712
    • contains: 254 b/w illus. 135 colour illus. 156 tables
    • availability: Adobe Reader ebooks available from eBooks.com
  • Table of Contents

    Preface
    Part I. Pathophysiology of Pediatric Liver Disease:
    1. Liver development Yiwei Zong and Joshua R. Friedman
    2. Functional development of the liver Frederick J. Suchy
    3. Mechanisms of bile formation and cholestasis Nitika A. Gupta and Saul J. Karpen
    4. Acute liver failure in children Robert H. Squires and Estella M. Alonso
    5. Cirrhosis and chronic liver failure Evelyn K. Hsu and Karen F. Murray
    6. Portal hypertension Benjamin L. Shneider
    7. Laboratory assessment of liver function and injury in children Vicky Lee Ng
    Part II. Cholestatic Liver Disease:
    8. Approach to the infant with cholestasis Amy Feldman and Frederick J. Suchy
    9. Medical and nutritional management of cholestasis in infants and children Andrew P. Feranchak, Frederick J. Suchy and Ronald J. Sokol
    10. Neonatal hepatitis and congenital infections Philip Rosenthal
    11. Biliary atresia and other disorders of the extrahepatic bile ducts William F. Balistreri, Jorge A. Bezerra and Frederick C. Ryckman
    12. Neonatal jaundice and disorders of bilirubin metabolism Mark Bartlett and Glenn R. Gourley
    13. Familial hepatocellular cholestasis Frederick J. Suchy, Shikha S. Sundaram and Benjamin L. Shneider
    14. Alagille syndrome Binita M. Kamath, Nancy B. Spinner and David A. Piccoli
    15. Intestinal failure associated liver disease Jason Soden and Ronald J. Sokol
    16. Disease of the gallbladder in infancy, childhood, and adolescence Frank W. DiPaola and James E. Heubi
    Part III. Hepatitis and Immune Disorders:
    17. Hepatitis A and hepatitis E virus infection Philip Rosenthal
    18. Hepatitis B virus infection Mei-Hwei Chang
    19. Hepatitis C virus infection Maureen M. Jonas
    20. Autoimmune hepatitis Nanda Kerkar and Cara L. Mack
    21. Sclerosing cholangitis Alexander G. Miethke and William F. Balistreri
    22. Drug-induced liver disease Eve A. Roberts
    23. Liver disease in immunodeficiencies Nedim Hadžić
    Part IV. Metabolic Liver Disease:
    24. Laboratory diagnosis of inborn errors of metabolism Piero Rinaldo
    25. α1-antitrypsin deficiency David H. Perlmutter
    26. Cystic fibrosis liver disease Meghana Sathe and Andrew P. Feranchak
    27. Inborn errors of carbohydrate metabolism Rana F. Ammoury and Fayez K. Ghishan
    28. Copper metabolism and copper storage disorders Ronald J. Sokol
    29. Iron storage disorders Michael R. Narkewicz and Peter F. Whittington
    30. Heme biosynthesis and the porphyrias Robert J. Desnick, Manisha Balwani and Karl E. Anderson
    31. Tyrosinemia Grant Mitchell, Pierre A. Russo, Josée Dubois and Fernando Alvarez
    32. Lysosomal storage disorders T. Andrew Burrow and Gregory A. Grabowski
    33. Disorders of bile acid synthesis and metabolism Kenneth D. R. Setchell
    34. Inborn errors of fatty acid oxidation Melanie B. Gillingham and Robert B. Steiner
    35. Mitochondrial hepatopathies Ronald J. Sokol
    36. Nonalcoholic fatty liver disease in children Rohit Kohli, Kevin E. Bove and Stavra A. Xanthakos
    37. Peroxisomal diseases Paul A. Watkins and Kathleen B. Schwarz
    38. Urea cycle disorders Derek Wong and Stephen Cederbaum
    Part V. Other Considerations and Issues in Pediatric Hepatology:
    39. Bacterial, parasitic, and fungal infections of the liver Donald A. Novak, Gregory Y. Lauwers and Richard L. Kradin
    40. Systemic disease and the liver Kathleen M. Campbell
    41. Fibrocystic liver disease Ronen Arnon, Maureen M. Jonas, Antonio R. Perez-Atayde and Frederick J. Suchy
    42. Tumors of the liver Dolores López-Terrada and Milton J. Finegold
    43. Liver transplantation in children: indications and surgical aspects M. Kyle Jensen, Maria H. Alonso, Jaimie D. Nathan, Frederick C. Ryckman, Gregory M. Tiao and William F. Balistreri
    44. Liver transplantation in children: post-transplant care Estella M. Alonso and Riccardo A. Superina
    Index.

  • Editors

    Frederick J. Suchy, University of Colorado Medical Center
    Frederick J. Suchy, MD is Chief Research Officer and Director, The Children's Hospital Research Institute, Children's Hospital Colorado. He is also Professor of Pediatrics and Associate Dean for Child Health Research, University of Colorado School of Medicine, Aurora, CO, USA.

    Ronald J. Sokol, University of Colorado Medical Center
    Ronald J. Sokol, MD is Professor and Vice Chair of Pediatrics, Section Head, Gastroenterology, Hepatology and Nutrition, Director, Colorado Clinical and Translational Sciences Institute, and holds the Arnold Silverman MD Chair in Digestive Health, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.

    William F. Balistreri, University of Cincinnati College of Medicine
    William F. Balistreri, MD is Director Emeritus of the Pediatric Liver Care Center, Medical Director Emeritus, Liver Transplantation, and Dorothy M. M. Kersten Professor of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition at the Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

    Contributors

    Yiwei Zong, Joshua R. Friedman, Frederick J. Suchy, Nitika A. Gupta, Saul J. Karpen, Robert H. Squires, Estella M. Alonso, Evelyn K. Hsu, Karen F. Murray, Benjamin L. Shneider, Vicky Lee Ng, Amy Feldman, Andrew P. Feranchak, Ronald J. Sokol, Philip Rosenthal, William F. Balistreri, Jorge A. Bezerra, Frederick C. Ryckman, Mark Bartlett, Glenn R. Gourley, Shikha S. Sundaram, Binita M. Kamath, Nancy B. Spinner, David A. Piccoli, Jason Soden, Frank W. DiPaola, James E. Heubi, Mei-Hwei Chang, Maureen M. Jonas, Nanda Kerkar, Cara L. Mack, Alexander G. Miethke, Eve A. Roberts, Nedim Hadžić, Piero Rinaldo, David H. Perlmutter, Meghana Sathe, Rana F. Ammoury, Fayez K. Ghishan, Michael R. Narkewicz, Peter F. Whittington, Robert J. Desnick, Manisha Balwani, Karl E. Anderson, Grant Mitchell, Pierre A. Russo, Josée Dubois, Fernando Alvarez, T. Andrew Burrow, Gregory A. Grabowski, Kenneth D. R. Setchell, Melanie B. Gillingham, Robert B. Steiner, Rohit Kohli, Kevin E. Bove, Stavra A. Xanthakos, Paul A. Watkins, Kathleen B. Schwarz, Derek Wong, Stephen Cederbaum, Donald A. Novak, Gregory Y. Lauwers, Richard L. Kradin, Kathleen M. Campbell, Ronen Arnon, Antonio R. Perez-Atayde, Dolores López-Terrada, Milton J. Finegold, M. Kyle Jensen, Maria H. Alonso, Jaimie D. Nathan, Gregory M. Tiao, Riccardo A. Superina

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