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Cambridge Textbook of Effective Treatments in Psychiatry


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Cambridge Textbook of Effective Treatments in Psychiatry

Cambridge University Press
9780521842280 - Cambridge Textbook of Effective Treatments in Psychiatry - by Peter Tyrer and Kenneth R. Silk

Cambridge Textbook of Effective Treatments in Psychiatry

This is a book of psychiatry at its most practical level. It aims to answer the sorts of questions psychiatrists ask on a daily basis. What treatments are available for the condition that I think this patient has? What is the relative value of each of these treatments? Are there any other treatments that I should be considering if a first approach has failed? Is there any value in combinations of treatment? And, can I be sure that the evidence and recommendations I read are free from bias?

The content is organised into three major parts. After an introductory section discussing the nature and classification of psychiatric disorders and the inherent problems of these diagnostic systems, the coverage moves on, in Part II, to review the major modalities of treatment and the priniciples involved. The core of the book is Part III, where treatments are discussed according to the diagnostic groupings. In almost all cases, the chapters have been written as partnerships, or group efforts, involving internationally recognised experts from North America and Europe, with synthesis of their recommendations.

All professionals in mental health want to give the best treatments for their patients. This book provides clinicians with the knowledge and guidance to achieve this aim.

Peter Tyrer is Professor of Community Psychiatry in the Department of Psychological Medicine, Imperial College, London, UK.

Kenneth R. Silk is Professor of Psychiatry and Director of the Personality Disorders Program in the Department of Psychiatry at the University of Michigan Medical School, Ann Arbor, USA.

Cambridge Textbook of Effective Treatments in Psychiatry

Peter Tyrer and Kenneth R. Silk

Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo

Cambridge University Press
The Edinburgh Building, Cambridge CB2 8RU, UK

Published in the United States of America by Cambridge University Press, New York
Information on this title:

© Cambridge University Press 2008

This publication is in copyright. Subject to statutory exception
and to the provisions of relevant collective licensing agreements,
no reproduction of any part may take place without
the written permission of Cambridge University Press.

First published 2008

Printed in the United Kingdom at the University Press, Cambridge

A catalogue record for this publication is available from the British Library

ISBN 978-0-521-84228-0 hardback

Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate.

Every effort has been made in preparing this publication to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use.


List of contributorspage ix
Part I Introduction
1Classification of psychiatric disorders and their principal treatments
Peter Tyrer and Kenneth R. Silk
2The history of psychiatric therapies
German E. Berrios
Part II Summary of treatment modalities in psychiatric disorders
3A critical assessment of methods and processes used to develop psychiatric drug treatments
George W. Arana and David J. Nutt
4Section I – The efficacy and safety of electroconvulsive therapy
Daniel Maixner and Michael A. Taylor
Section II – Focal brain stimulation approaches to psychiatric treatment
Antonio Mantovani, Arielle D. Stanford, Peter Bulow and Sarah H. Lisanby
5The effectiveness of psychological treatments in psychiatry
Peter Fonagy and Joel Paris
6Educational interventions
Christopher Dowrick, Nancee Blum and Bruce Pfohl
7Complementary and alternative medicine
Sally Guthrie and George Lewith
8Complex interventions
Peter Tyrer and Karen Milner
Part III Specific treatments
Organic disorders
Section editors
James Warner and Robert van Reekum
Laura Gage and David K. Conn
10Management of behavioural and psychological symptoms of dementia and acquired brain injury
Joel Sadavoy, Krista L. Lanctôt and Shoumitro Deb
11Dementia: pharmacological and non-pharmacological treatments and guideline review
Martine Simard and Elizabeth L. Sampson
12Pharmacological treatment of psychosis and depression in neurological disease in older adults
Mark Rapoport, Cara Brown and Craig Ritchie
Section editors
Kirk J. Brower and Mike Crawford
13Psychological treatments of alcohol use disorders
Deirdre Conroy, Kirk J. Brower, Jane Marshall and Mike Crawford
14Pharmacotherapy of alcohol misuse, dependence and withdrawal
George A. Kenna, Kostas Agath and Robert Swift
15Educational interventions for alcohol use disorders
Robert Patton, Kirk J. Brower, Shannon Bellefleur and Mike Crawford
16Complex interventions for alcohol use disorders
Valerie J. Slaymaker, Kirk J. Brower and Mike Crawford
17Complementary and alternative medicine for alcohol misuse
Elizabeth A. R. Robinson, Stephen Strobbe and Kirk J. Brower
Drug misuse
Section editors
Owen Bowden-Jones and Tony P. George
18Empirically validated psychological therapies for drug dependence
Tara M. Neavins, Caroline J. Easton, Janet Brotchie and Kathleen M. Carroll
19Treatment of stimulant dependence
Mehmet Sofuoglu, Kostas Agath and Thomas R. Kosten
20Treatment of opioid dependence
Leslie L. Buckley, Nicholas Seivewright, Mark Parry, Abhijeetha Salvaji and Richard Schottenfeld
21Treatment of sedative-hypnotic dependence
Karim Dar and Manoj Kumar
22Treatment of cannabis dependence
Brent A. Moore, Henrietta Bowden-Jones, Alan J. Budney and Ryan Vandrey
23Treatment of nicotine dependence
Andrea H. Weinberger, Pamela Walters, Taryn M. Allen, Melissa M. Dudas, Kristi A. Sacco and Tony P. George
24Treatment of co-occurring psychiatric and substance use disorders
Douglas M. Ziedonis, Ed. Day, Erin L. O’Hea, Jonathan Krejci, Jeffrey A. Berman and David Smelson
Section editors
Stephen R. Marder and Peter B. Jones
25Pharmacological treatments for schizophrenia
Stephen R. Marder and Peter B. Jones
26Psychosocial and pharmacological treatments for schizophrenia
Peter B. Jones and Stephen R. Marder
Mood disorders
Section editors
William H. Coryell and John Geddes
27Psychopharmacology of mood disorders
William H. Coryell and John Geddes
28Efficacy of brain stimulation and neurosurgical procedures for treatment of mood disorders
Kunal K. Patra and Edward Coffey
29Psychotherapy for depression: current empirical status and future directions
Scott Temple and John Geddes
30Alternative therapies for mood disorders
William H. Coryell
Anxiety and neurotic disorders
Section editors
Peter Tyrer and Randall D. Marshall
31Treatment of generalised anxiety and somatoform disorders
Peter Tyrer and David Baldwin
32Panic disorder
Stacy Shaw Welch, Michelle Craske, Murray B. Stein, Phil Harrison-Read and Peter Roy-Byrne
33Specific phobias and agoraphobia
Sonya B. Norman and Ariel J. Lang
34Social phobia
Laura Campbell-Sills and Murray B. Stein
35Obsessive-compulsive disorder
Helen Blair Simpson and Phil Harrison-Read
36Post-traumatic stress disorders and adjustment disorders
Randall D. Marshall, Steven B. Rudin and Peter Tyrer
Eating disorders
Section editors
Ulrike Schmidt and Katherine Halmi
37Psychopharmacology of eating disorders
Andrew Bennett, Rishi Caleyachetty and Janet Treasure
38Other somatic physical treatments and complex interventions for eating disorders
Philippa Hugo and Scott Crow
39Psychological treatments for eating disorders
Roz Shafran, Pamela K. Keel, Alissa Haedt and Christopher Fairburn
40Educational interventions for eating disorders
Mima Simic, Pauline S. Powers and Yvonne Bannon
41Alternative treatments for eating disorders
Pauline S. Powers, Yvonne Bannon and Adrienne J. Key
42Complex treatments for eating disorders
Scott Crow and Ulrike Schmidt
Personality disorders
Section editors
Anthony Bateman and Mary Zanarini
43Personality disorder
Anthony Bateman and Mary Zanarini
44Other treatments for persistent disturbances of behaviour
Peter Tyrer and Stephen Tyrer
Sexual and gender identity disorders
Section editors
Michael King and James Barrett
45Effectiveness of treatments of sexual disorders
Michael King
46Disorders of gender identity
James Barrett
Child psychiatry
Section editors
Matthew Hodes and Christopher K. Varley
47Psychological treatments for children and adolescents
Brian W. Jacobs, Stefanie A. Hlastala and Elizabeth McCauley
48Drugs and other physical treatments
Brian W. Jacobs, Jennifer A. Varley and Jon McClellan
49Educational interventions and alternative treatments
Brian W. Jacobs, Michael Storck, Ann Vander Stoep and Wendy Weber
50Attachment insecurity and attachment disorder
Jonathan Green, Ming Wai Wan and Michelle DeKlyen
51Feeding and sleeping disorders in infancy and early childhood
Heather Carmichael Olson, Nancy C. Winters, Sally L. Davidson Ward and Matthew Hodes
52Evaluating interventions for children with autism and intellectual disabilities
Patricia Howlin and Hower Kwon
53ADHD and hyperkinetic disorder
Paramala J. Santosh, Amy Henry and Christopher K. Varley
54Oppositional defiant disorder and conduct disorder
Brent Collett, Stephen Scott, Carol Rockhill, Matthew Speltz and Jon McClellan
55Treatment of depressive disorders in children and adolescents
Kelly Schloredt, Rachel Gershenson, Christopher K. Varley, Paul Wilkinson and Ian Goodyer
56Treatment of psychoses in children and adolescents
Anthony James and Jon McClellan
57Anxiety disorders
Christopher K. Varley, Angeles Diaz-Caneja and Elena Garralda
58Treatment of eating disorders in children and adolescents
Matthew Hodes, Rose Calderon, Cora Collette Breuner and Christopher K. Varley
Appendix I: Summary of specific drugs having evidence of effectiveness in mental disorders
Michele Sie and Sally Guthrie
Appendix II: Key to effectiveness tables867


Kostas Agath
Westminster Substance Misuse Services
London, UK

Taryn M. Allen
Department of Psychiatry
Yale University School of Medicine,

George W. Arana
Mental Health Service
RHJ VA Medical Center
South Carolina, USA

David Baldwin
Clinical Neuroscience Division
University of Southampton
RSH Hospital
Southampton, UK

Yvonne Bannon
University of South Florida
College of Medicine
Department of Psychiatry and Behavioural Medicine
Tampa, FL, USA

James Barrett
Charing Cross Hospital
Gender Identity Clinic, Claybrook Centre
London, UK

Anthony Bateman
Halliwick Unit
St Ann’s Hospital, St Ann’s Road
London, UK

Shannon Bellefleur
University of Michigan
Addiction Psychiatry Training Program
Ann Arbor, MI, USA

Andrew Bennett
Weill Cornell Medical School
White Plains, NY, USA

Jeffrey A. Berman
Department of Psychiatry
Robert Wood Johnson Medical School
VA Health Care System
New Jersey, NJ, USA

German E. Berrios
University of Cambridge
Addenbroke’s Hospital
Cambridge, UK

Nancee Blum
University of Iowa
2880 JPP
Iowa City
Iowa, USA

Henrietta Bowden-Jones
Substance Misuse Services
Central North West London
Mental Health NHS Trust,
London, UK

Owen Bowden-Jones
Drug Treatment Centre
Chelsea and Westminster Hospital
London, UK

Cora Collette Breuner
Childrens’ Hospital and Medical Center
Washington, USA

Janet Brotchie
Lead Psychologist in Substance Misuse
Central and North West London Mental Health NHS Trust
London, UK

Kirk J. Brower
University of Michigan Addiction Research Center
Rachel Upjohn Building
Ann Arbor, MI, USA

Cara Brown
University of Toronto
Toronto, ON, Canada

Leslie L. Buckley
University Health Network
Toronto, ON, Canada

Alan J. Budney
Department of Psychiatry
University of Arkansas for Medical Sciences
Little Rock, AR, USA

Peter Bulow
Department of Psychiatry
Division of Brain Stimulation and Therapeutic Modulation
New York State Psychiatric Institute

Rose Calderon
Department of Child and Adolescent Psychiatry
University of Washington Medical School
Seattle, WA, USA

Rishi Caleyachetty
GKT Medical School
Guys Campus
London, UK

Laura Campbell-Sills
University of California
San DiegoLa
Jolla, CA, USA

Kathleen M. Carroll
Division of Substance Abuse
Yale University School of Medicine
New Haven, CT, USA

Edward Coffey
Department of Psychiatry
Henry Ford Health System
Detroit, MI, USA

© Cambridge University Press

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