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Marijuana and Madness
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  • 14 b/w illus. 10 tables
  • Page extent: 236 pages
  • Size: 247 x 174 mm
  • Weight: 0.63 kg

Library of Congress

  • Dewey number: 615/.7827
  • Dewey version: 22
  • LC Classification: RC568.C2 M375 2004
  • LC Subject headings:
    • Marijuana--Physiological effect
    • Marijuana--Psychological aspects
    • Marijuana abuse--Complications
    • Psychoses--Etiology
    • Schizophrenia--Etiology

Library of Congress Record


 (ISBN-13: 9780521819404 | ISBN-10: 0521819407)

Replaced by 9781107000216


This comprehensive and up-to-date overview of the psychiatry and neuroscience of Cannabis sativa (marijuana) places particular emphasis on psychotic disorders. It outlines the latest research enhancing our knowledge of the human cannabinoid system, and links it to clinical and epidemiological facts about the impact of cannabis on mental health. Controversial issues are critically explored, including whether a discrete "cannabis psychosis" exists.


1. The cannabinoid system: from the point of view of a chemist Raphael Mechoulam and L. Hanu; 2. How cannabis works in the brain Leslie Iversen; 3. Acute and subacute psychomimetic effects of cannabis in humans David Castle and Nadia Solowij; 4. The association between cannabis use and depression: a review of the evidence Louisa Degenhardt, Wayne Hall, Michael Lynskey, Carolyn Coffey and George Patton; 5. Cannabis and psychosis proneness Helene Verdoux; 6. Is there a specific 'cannabis psychosis'? Wayne Hall and Louisa Degenhardt; 7. Cannabis as a potential causal factor in schizophrenia Louise Arseneault, Mary Cannon, John Witton and Robin Murray; 8. Cannabis abuse and the course of schizophrenia D. H. Linszen, Lieuwe de Haan and Bart Peters; 9. The endogenous cannabinoid system in schizophrenia Suresh Sundram, Brian Dean and David Copolov; 10. A cannabinoid 'model' psychosis, dopamine-cannabinoid interactions and implications for schizophrenia Cyril D'Souza, Hyung-San Cho, Edward Perry and John H. Krystal; 11. Motives that maintain cannabis use among individuals with psychotic disorders Catherine Spencer; 12. Addressing cannabis abuse in people with psychosis Wynne James; 13. Residual cognitive effects of long-term cannabis use Harrison Pope, Jr. and Deborah Yurgelun-Todd.

Prize Winner

BMA Medical Book Competition-First Prize in Mental Health Category (9/05)


"We congratulate them (the authors) on their accomplishment and recommend this book enthusiastically for all clinicians and researchers interested in substance related issues."
Journal of American Medical Association (JAMA), Shahla Modir, MD, UCLA Neuropsychiatric Institute, and John Tsuang, MD, Harbor-UCLA Medical Center

"Researchers in these areas will benefit by the excellent literature reviews and assembly of information. As they say in the Movie Show: 'I'll give it four stars: how about you?'
Australian Medicine, Dr. Chris Cantor

"Marijuana and Madness is an excellent book that clearly and thoroughly explores the subject from every point of the biopsychosocial spectrum."
Journal of Clinical Psychiatry

"Reading Marijuana and Madness will make you humble and wary of scientific and clinicin zealots and will increase your wisdom."
Journal of Clinical Psychiatry, Willim S. Appleton, Harvard Medical School

"This book provides an excellent and unparalleled overview of current evidence-based thinking about cannabis and psychotic disorders, and should be read by anyone involved in clinical practice or research with people who suffer serious metal illness and also use cannabis."
Australian and New Zealand Journal of Psychiatry, Fraser Todd

"...I highly recommend this book to all clinicians who wish for an update on the many intriguing questions about cannabis use and mental helath raised by our colleagues, our patients, and the public. I cannot think of a better reference at this point."
The Canadian Journal of Psychiatry, Nady el-Guebaly, MD

"I found this to be an excellent, short monograph...the publication of a monograph on marijuana and Madness is both important and timely. Hopefully it will be widely read and digested not only by mental health professionals but also by legislators before any attempts are made to change the law in those countries in which the possession of cannabis is a criminal offense."
Quarterly Journal of Mental Health, Brian E. Leonard, National University of Ireland

"The editors' succeed admirable in their aim with comprehensive review chapters ranging from descriptions of the endocannabinoid system to 'cannabis psychosis' to the relationship between cannabis abuse and the course of schizophrenia."
Bill Wood MD, Journal of the Canadian Academy of Child and Adolescent Psychiatry


Raphael Mechoulam, L. Hanu, Leslie Iversen, David Castle, Nadia Solowij, Wayne Hall, Louisa Degenhardt, Michael Lynskey, Carolyn Coffey, George Patton, Helene Verdoux, Mary Cannon, Louise Arseneault, John Witton, Robin Murray, D. H. Linszen, Lieuwe de Haan, Bart Peters, Suresh Sundram, Brian Dean, David Copolov, Cyril D'Souza, Hyung-San Cho, Edward Perry, John H. Krystal, Catherine Spencer, Wynne James, Harrison Pope, Jr., Deborah Yurgelun-Todd

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